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Research ArticleORIGINAL RESEARCH

Development and Validation of the COVID-NoLab and COVID-SimpleLab Risk Scores for Prognosis in 6 US Health Systems

Mark H. Ebell, Xinyan Cai, Robert Lennon, Derjung M. Tarn, Arch G. Mainous, Aleksandra E. Zgierska, Bruce Barrett, Wen-Jan Tuan, Kevin Maloy, Munish Goyal and Alex Krist
The Journal of the American Board of Family Medicine February 2021, 34 (Supplement) S127-S135; DOI: https://doi.org/10.3122/jabfm.2021.S1.200464
Mark H. Ebell
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD, MS
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Xinyan Cai
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MPH
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Robert Lennon
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD
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Derjung M. Tarn
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD, PhD
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Arch G. Mainous III
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
PhD
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Aleksandra E. Zgierska
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD, PhD
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Bruce Barrett
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD, PhD
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Wen-Jan Tuan
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
DHA, MS, MPH
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Kevin Maloy
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD
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Munish Goyal
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD
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Alex Krist
From the Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens (MHE, XC); Department of Family and Community Medicine, Penn State College of Medicine, Hershey (RL); Department of Family Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles (DMT); Department of Health Services Research, Management and Policy, University of Florida, Gainesville (AGM); Departments of Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey (AEZ); Department of Family Medicine and Community Health, University of Wisconsin, Madison (BB, WJT); Department of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC (KM, MG); Department of Family Medicine, Virginia Commonwealth University, Richmond (AK).
MD, MPH
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The Journal of the American Board of Family  Medicine: 34 (Supplement)
The Journal of the American Board of Family Medicine
Vol. 34, Issue Supplement
February 2021
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Development and Validation of the COVID-NoLab and COVID-SimpleLab Risk Scores for Prognosis in 6 US Health Systems
Mark H. Ebell, Xinyan Cai, Robert Lennon, Derjung M. Tarn, Arch G. Mainous, Aleksandra E. Zgierska, Bruce Barrett, Wen-Jan Tuan, Kevin Maloy, Munish Goyal, Alex Krist
The Journal of the American Board of Family Medicine Feb 2021, 34 (Supplement) S127-S135; DOI: 10.3122/jabfm.2021.S1.200464

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Development and Validation of the COVID-NoLab and COVID-SimpleLab Risk Scores for Prognosis in 6 US Health Systems
Mark H. Ebell, Xinyan Cai, Robert Lennon, Derjung M. Tarn, Arch G. Mainous, Aleksandra E. Zgierska, Bruce Barrett, Wen-Jan Tuan, Kevin Maloy, Munish Goyal, Alex Krist
The Journal of the American Board of Family Medicine Feb 2021, 34 (Supplement) S127-S135; DOI: 10.3122/jabfm.2021.S1.200464
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    • Appendix 1. Full List of Requested Clinical Variables; Predictor Variables only Included if Ordered Within 24 Hours of Admission
    • Appendix 2. This Summarizes the Receiver Operating Characteristic (ROC) Curves and Calibration Plots for Each Model.
    • Appendix 3. Additional Model Using Clinical Variables and Complete Blood Count Only.
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