To Treat or Not to Treat? Effect of Urate-Lowering Therapy on Renal Function, Blood Pressure and Safety in Patients with Asymptomatic Hyperuricemia: A Systematic Review and Network Meta-Analysis

From the Department of Family Medicine, Hsinchu Cathay General Hospital, Hsinchu, Taiwan (YYT); Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan (YYT, MCS, HKH, YKT); Department of Nephrology, Taipei City Hospital, Renai Branch, Taipei, Taiwan (CPT); Department of Family Medicine, Hualian Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan (HKH); Department of Family Medicine, Cathay General Hospital, Taipei, Taiwan (YYT); Department of Dentistry, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan (YKT).

From the Department of Family Medicine, Hsinchu Cathay General Hospital, Hsinchu, Taiwan (YYT); Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan (YYT, MCS, HKH, YKT); Department of Nephrology, Taipei City Hospital, Renai Branch, Taipei, Taiwan (CPT); Department of Family Medicine, Hualian Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan (HKH); Department of Family Medicine, Cathay General Hospital, Taipei, Taiwan (YYT); Department of Dentistry, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan (YKT).

From the Department of Family Medicine, Hsinchu Cathay General Hospital, Hsinchu, Taiwan (YYT); Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan (YYT, MCS, HKH, YKT); Department of Nephrology, Taipei City Hospital, Renai Branch, Taipei, Taiwan (CPT); Department of Family Medicine, Hualian Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan (HKH); Department of Family Medicine, Cathay General Hospital, Taipei, Taiwan (YYT); Department of Dentistry, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan (YKT).

From the Department of Family Medicine, Hsinchu Cathay General Hospital, Hsinchu, Taiwan (YYT); Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan (YYT, MCS, HKH, YKT); Department of Nephrology, Taipei City Hospital, Renai Branch, Taipei, Taiwan (CPT); Department of Family Medicine, Hualian Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan (HKH); Department of Family Medicine, Cathay General Hospital, Taipei, Taiwan (YYT); Department of Dentistry, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan (YKT).

From the Department of Family Medicine, Hsinchu Cathay General Hospital, Hsinchu, Taiwan (YYT); Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan (YYT, MCS, HKH, YKT); Department of Nephrology, Taipei City Hospital, Renai Branch, Taipei, Taiwan (CPT); Department of Family Medicine, Hualian Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan (HKH); Department of Family Medicine, Cathay General Hospital, Taipei, Taiwan (YYT); Department of Dentistry, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan (YKT).