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Research ArticleOriginal Research

Antidepressant Medication Use for Primary Care Patients with and without Medical Comorbidities: A National Electronic Health Record (EHR) Network Study

James M. Gill, Michael S. Klinkman and Ying Xia Chen
The Journal of the American Board of Family Medicine July 2010, 23 (4) 499-508; DOI: https://doi.org/10.3122/jabfm.2010.04.090299
James M. Gill
MD, MPH
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Michael S. Klinkman
MS, MD
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Ying Xia Chen
MS
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References

  1. ↵
    Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 593–602.
    OpenUrlCrossRefPubMedWeb of Science
  2. ↵
    Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 617–27.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    Klinkman MS, Okkes I. Mental health problems in primary care a research agenda. J Fam Pract 1998; 47: 379–84.
    OpenUrlPubMedWeb of Science
  4. ↵
    Unutzer J, Katon W, Sullivan M, Miranda J. Treating depressed older adults in primary care: narrowing the gap between efficacy and effectiveness. Milbank Q 1999; 77: 225–56.
    OpenUrlCrossRefPubMedWeb of Science
  5. ↵
    Katon W, Sullivan MD. Depression and chronic medical illness. J Clin Psychiatry 1990; 51(Suppl): 3–11; discussion, 12–4.
    OpenUrlPubMedWeb of Science
  6. ↵
    Egede LE, Zheng D, Simpson K. Comorbid depression is associated with increased health care use and expenditures in individuals with diabetes. Diabetes Care 2002; 25: 464–70.
    OpenUrlAbstract/FREE Full Text
  7. ↵
    Whyte EM, Mulsant BH, Vanderbilt J, et al. Depression after stroke: a prospective epidemiological study. J Am Geriatr Soc 2004; 52: 774–8.
    OpenUrlCrossRefPubMedWeb of Science
  8. ↵
    Guck TP, Kavan MG, Elsasser GN, Barone EJ. Assessment and treatment of depression following myocardial infarction. Am Fam Physician 2001; 64: 641–8.
    OpenUrlPubMedWeb of Science
  9. Ormel J, Von Korff M, Burger H, et al. Mental disorders among persons with heart disease—results from World Mental Health surveys. Gen Hosp Psychiatry 2007; 29: 325–34.
    OpenUrlPubMed
  10. ↵
    Lichtman JH, Bigger JT Jr, Blumenthal JA, et al. Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation 2008; 118: 1768–75.
    OpenUrlAbstract/FREE Full Text
  11. Ziegelstein RC. Depression after myocardial infarction. Cardiol Rev 2001; 9: 45–51.
    OpenUrlCrossRefPubMed
  12. ↵
    Patten SB, Williams JVA. Chronic obstructive lung diseases and prevalence of mood, anxiety, and substance-use disorders in a large population sample. Psychosomatics 2007; 48: 496–501.
    OpenUrlCrossRefPubMed
  13. ↵
    Meyer HA, Sinnott C, Seed PT. Depressive symptoms in advanced cancer. Part 2. Depression over time; the role of the palliative care professional. Palliat Med 2003; 17: 604–7.
    OpenUrlAbstract/FREE Full Text
  14. Massie M. Prevalence of depression in patients with cancer. J Natl Cancer Inst Monogr 2004; 32: 57–71.
    OpenUrlAbstract/FREE Full Text
  15. Spiegel D. Cancer and depression. Br J Psychiatry Suppl 1996; (30): 109–16.
    OpenUrl
  16. ↵
    Rush WA, Whitebird RR, Rush MR, Solberg LI, O’Connor PJ. Depression in patients with diabetes: does it impact clinical goals? J Am Board Fam Med 2008; 21: 392–7.
    OpenUrlAbstract/FREE Full Text
  17. ↵
    Egede LE, Nietert PJ, Zheng D. Depression and all-cause and coronary heart disease mortality among adults with and without diabetes. Diabetes Care 2005; 28: 1339–45.
    OpenUrlAbstract/FREE Full Text
  18. ↵
    Lin EHB, Heckbert SR, Rutter CM, et al. Depression and increased mortality in diabetes: unexpected causes of death. Ann Fam Med 2009; 7: 414–21.
    OpenUrlAbstract/FREE Full Text
  19. ↵
    Lauzon C, Beck CA, Huynh T, et al. Depression and prognosis following hospital admission because of acute myocardial infarction [see comment]. CMAJ 2003; 168: 547–52.
    OpenUrl
  20. ↵
    Carney RM, Freedland KE, Steinmeyer B, et al. Depression and 5-year survival following acute myocardial infarction: a prospective study. J Affect Disord 2008; 109: 133–8.
    OpenUrlCrossRefPubMedWeb of Science
  21. ↵
    Jia H, Damush TM, Qin H, et al. The impact of poststroke depression on healthcare use by veterans with acute stroke. Stroke 2006; 37: 2796–801.
    OpenUrlAbstract/FREE Full Text
  22. ↵
    Watson M, Haviland JS, Greer S, Davidson J, Bliss JM. Influence of psychological response on survival in breast cancer: a population-based cohort study. Lancet 1999; 354: 1331–6.
    OpenUrlCrossRefPubMedWeb of Science
  23. ↵
    Smith GF, Toonen TR. Primary care of the patient with cancer. Am Fam Physician 2007; 75: 1207–14.
    OpenUrlPubMedWeb of Science
  24. ↵
    Smoller JW, Allison M, Cochrane BB, et al. Antidepressant use and risk of incident cardiovascular morbidity and mortality among postmenopausal women in the Women's Health Initiative study. Arch Int Med 2009; 169: 2128–39.
    OpenUrlCrossRefPubMedWeb of Science
  25. ↵
    Gill JM, Chen YX, Lieberman MI. Management of depression in ambulatory care for patients with medical co-morbidities: a study from a national electronic health record (EHR) network. Int J Psychiatry Med 2008; 38: 203–15.
    OpenUrlCrossRefPubMed
  26. Gill J, Chen YX. Quality of lipid management in outpatient care: a national study using electronic health records. Am J Med Qual 2008; 23: 75–381.
    OpenUrl
  27. Gill JM, Fleischut P, Haas S, Pellini B, Crawford A, Nash DB. Use of antibiotics for adult upper respiratory infections in outpatient settings: a national ambulatory network study. Fam Med 2006; 38: 349–54.
    OpenUrlPubMedWeb of Science
  28. Gill JM, Foy AJ, Ling Y. Quality of outpatient care for diabetes mellitus in a national electronic health record network. Am J Med Qual 2006; 21: 13–7.
    OpenUrlAbstract/FREE Full Text
  29. ↵
    Gill JM, Chen YX, Glutting JJ, Diamond JJ, Lieberman MI. Impact of decision support in electronic medical records on lipid management in primary care. Popul Health Manag 2009; 12: 221–6.
    OpenUrlCrossRefPubMedWeb of Science
  30. ↵
    Fournier JC, DeRubeis RJ, Hollon SD, et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA 2010; 303: 47–53.
    OpenUrlCrossRefPubMedWeb of Science
  31. ↵
    Therapeutic Guidelines, Ltd. Therapeutic guidelines: psychotropic. 5 ed. North Melbourne: Therapeutic Guidelines, Ltd.; 2003.
  32. ↵
    de Groot M, Anderson R, Freedland KE, Clouse RE, Lustman PJ. Association of depression and diabetes complications: a meta-analysis. Psychosom Med 2001; 63: 619–30.
    OpenUrlAbstract/FREE Full Text
  33. ↵
    Frasure-Smith N, Lesperance F, Talajic M. Depression following myocardial infarction. Impact on 6-month survival. JAMA 1993; 270: 1819–25.
    OpenUrlCrossRefPubMedWeb of Science
  34. ↵
    Morris PL, Robinson RG, Samuels J. Depression, introversion and mortality following stroke. Aust N J Z Psychiatry 1993; 27: 443–9.
    OpenUrl
  35. ↵
    Mohapatra PK, Kar N, Kar GC, Behera M. Effectiveness of sertraline in treatment of depression in a consecutive sample of patients with acute myocardial infarction: six-month prospective study on outcome. Clin Pract Epidemiol Ment Health 2005; 1: 26.
    OpenUrlCrossRefPubMed
  36. ↵
    Taylor CB, Youngblood ME, Catellier D, et al. Effects of antidepressant medication on morbidity and mortality in depressed patients after myocardial infarction [see comment]. Arch Gen Psychiatry 2005; 62: 792–8.
    OpenUrl
  37. ↵
    Berkman LF, Blumenthal J, Burg M, et al. Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) randomized trial [see comment]. JAMA 2003; 289: 3106–16.
    OpenUrl
  38. ↵
    Jorge RE, Robinson RG, Arndt S, Starkstein S. Mortality and post-stroke depression: a placebo-controlled trial of antidepressants. Am J Psychiatry 2003; 160: 1823–9.
    OpenUrlCrossRefPubMedWeb of Science
  39. ↵
    Lustman P, Freedland K, Griffith L, Clouse R. Fluoxetine for depression in diabetes: a randomized double-blind placebo-controlled trial. Diabetes Care 2000; 23: 618–23.
    OpenUrlAbstract/FREE Full Text
  40. ↵
    Williams JW, Katon W, Lin EHB, et al. The effectiveness of depression care management on diabetes-related outcomes in older patients. Ann Intern Med 2004; 140: 1015–24.
    OpenUrlCrossRefPubMedWeb of Science
  41. ↵
    Lustman PJ, Griffith LS, Clouse RE, et al. Effects of nortriptyline on depression and glycemic control in diabetes: results of a double-blind, placebo-controlled trial. Psychosom Med 1997; 59: 241–50.
    OpenUrlAbstract/FREE Full Text
  42. ↵
    Thombs BDP, de Jonge PP, Coyne JCP, et al. Depression screening and patient outcomes in cardiovascular care: a systematic review. JAMA 2008; 300: 2161–71.
    OpenUrlCrossRefPubMedWeb of Science
  43. ↵
    Glassman AH, Roose SP, Bigger JT Jr. The safety of tricyclic antidepressants in cardiac patients. Risk-benefit reconsidered. JAMA 1993; 269: 2673–5.
    OpenUrlCrossRefPubMedWeb of Science
  44. ↵
    Lespérance F, Frasure-Smith N, Kosyzcki D, et al. Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease. JAMA 2007; 297: 367–79.
    OpenUrlCrossRefPubMedWeb of Science
  45. ↵
    Kharofa J, Sekar P, Haverbusch M, et al. Selective serotonin reuptake inhibitors and risk of hemorrhagic stroke. Stroke 2007; 38: 3049–51.
    OpenUrlAbstract/FREE Full Text
  46. Bak S, Tsiropoulos I, Kjaersgaard JO, et al. Selective serotonin reuptake inhibitors and the risk of stroke: a population-based case-control study. Stroke 2002; 33: 1465–73.
    OpenUrlAbstract/FREE Full Text
  47. de Abajo FJ, Jick H, Derby L, Jick S, Schmitz S. Intracranial haemorrhage and use of selective serotonin reuptake inhibitors. Br J Clin Pharmacol 2000; 50: 43–7.
    OpenUrlCrossRefPubMedWeb of Science
  48. ↵
    O’Connor CM, Jiang W, Kuchibhatla M, et al. Antidepressant use, depression, and survival in patients with heart failure. Arch Intern Med 2008; 168: 2232–7.
    OpenUrlCrossRefPubMedWeb of Science
  49. ↵
    Tata LJ, West J, Smith C, et al. General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction. Heart 2005; 91: 465–71.
    OpenUrlAbstract/FREE Full Text
  50. ↵
    Klinkman MS. Competing demands in psychosocial care. A model for the identification and treatment of depressive disorders in primary care [see comment]. Gen Hosp Psychiatry 1997; 19: 98–111.
    OpenUrl
  51. ↵
    Rost K, Nutting P, Smith J, Coyne JC, Cooper-Patrick L, Rubenstein L. The role of competing demands in the treatment provided primary care patients with major depression. Arch Fam Med 2000; 9: 150–4.
    OpenUrlCrossRefPubMedWeb of Science
  52. Nutting PA, Rost K, Smith J, Werner JJ, Elliot C. Competing demands from physical problems: effect on initiating and completing depression care over 6 months. Arch Fam Med 2000; 9: 1059–64.
    OpenUrlCrossRefPubMedWeb of Science
  53. Parchman ML, Pugh JA, Romero RL, Bowers KW. Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med 2007; 5: 196–201.
    OpenUrlAbstract/FREE Full Text
  54. Bayliss EA, Edwards AE, Steiner JF, Main DS. Processes of care desired by elderly patients with multimorbidities. Fam Pract 2008; 25: 287–93.
    OpenUrlAbstract/FREE Full Text
  55. ↵
    Lincoln NB, Flannaghan T. Cognitive behavioral psychotherapy for depression following stroke: a randomized controlled trial. Stroke 2003; 34: 111–5.
    OpenUrlAbstract/FREE Full Text
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The Journal of the American Board of Family Medicine: 23 (4)
The Journal of the American Board of Family Medicine
Vol. 23, Issue 4
July-August 2010
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Antidepressant Medication Use for Primary Care Patients with and without Medical Comorbidities: A National Electronic Health Record (EHR) Network Study
James M. Gill, Michael S. Klinkman, Ying Xia Chen
The Journal of the American Board of Family Medicine Jul 2010, 23 (4) 499-508; DOI: 10.3122/jabfm.2010.04.090299

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Antidepressant Medication Use for Primary Care Patients with and without Medical Comorbidities: A National Electronic Health Record (EHR) Network Study
James M. Gill, Michael S. Klinkman, Ying Xia Chen
The Journal of the American Board of Family Medicine Jul 2010, 23 (4) 499-508; DOI: 10.3122/jabfm.2010.04.090299
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