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Research ArticleOriginal Research

Effectiveness of Cinnamon for Lowering Hemoglobin A1C in Patients with Type 2 Diabetes: A Randomized, Controlled Trial

Paul Crawford
The Journal of the American Board of Family Medicine September 2009, 22 (5) 507-512; DOI: https://doi.org/10.3122/jabfm.2009.05.080093
Paul Crawford
MD
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References

  1. ↵
    Dugoua J, Seely D, Perri D, et al. From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark. Can J Physiol Pharmacol 2007; 85: 837–47.
    OpenUrlPubMed
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    Talpur N, Echard B, Ingram C, et al. Effects of a novel formulation of essential oils on glucose–insulin metabolism in diabetic and hypertensive rats: a pilot study. Diab Obes Metab 2005; 7: 193–9.
    OpenUrl
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    Kim SH, Hyun SH, Choung SY. Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice. J Ethnopharmacol 2006; 104: 119–23.
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  4. ↵
    Cao H, Polansky MM, Anderson RA. Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3–L1 adipocytes. Arch Biochem Biophys 2007; 459: 214–22.
    OpenUrlCrossRefPubMedWeb of Science
  5. ↵
    Peng X, Cheng K, Ma J, et al. Cinnamon bark proanthocyadins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. J Agric Food Chem 2008; 56: 1907–11.
    OpenUrlPubMed
  6. ↵
    Khan A, Khattak KN, Safdar M, Anderson RA, Ali Khan MM. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003; 26: 3215–8.
    OpenUrlAbstract/FREE Full Text
  7. ↵
    Vanschoonbeek K, Thomassen BL, Senden JM, Wodzig WK, van Loon LJ. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. J Nutr 2006; 136: 977–80.
    OpenUrlAbstract/FREE Full Text
  8. ↵
    Mang B, Wolters M, Schmitt B, et al. Effects of a cinnamon extract on plasma glucose, HbA1c, and serum lipids in diabetes mellitus type 2. Eur J Clin Invest 2006; 36: 340–4.
    OpenUrlCrossRefPubMedWeb of Science
  9. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007; 30: 813–6.
    OpenUrlAbstract/FREE Full Text
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    Blevins SM, Leyva MJ, Brown J, Wright J, Scofield RH, Aston CE. Effect of cinnamon on glucose and lipid levels in non insulin-dependent type 2 diabetes. Diabetes Care 2007; 30: 2236–7.
    OpenUrlFREE Full Text
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    Baker WL, Gutierrez-Williams G, White CM, Kluger J, Coleman CI. Effect of cinnamon on glucose control and lipid parameters. Diabetes Care 2008; 31: 41–3.
    OpenUrlAbstract/FREE Full Text
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    Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998; 352: 837–53.
    OpenUrlCrossRefPubMedWeb of Science
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The Journal of the American Board of Family Medicine: 22 (5)
The Journal of the American Board of Family Medicine
Vol. 22, Issue 5
September-October 2009
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Effectiveness of Cinnamon for Lowering Hemoglobin A1C in Patients with Type 2 Diabetes: A Randomized, Controlled Trial
Paul Crawford
The Journal of the American Board of Family Medicine Sep 2009, 22 (5) 507-512; DOI: 10.3122/jabfm.2009.05.080093

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Effectiveness of Cinnamon for Lowering Hemoglobin A1C in Patients with Type 2 Diabetes: A Randomized, Controlled Trial
Paul Crawford
The Journal of the American Board of Family Medicine Sep 2009, 22 (5) 507-512; DOI: 10.3122/jabfm.2009.05.080093
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