Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM on Bluesky
  • JABFM On Facebook
  • JABFM On Twitter
  • JABFM On YouTube
Brief ReportBrief Report

Excess Factor VIII: A Common Cause of Hypercoagulability

Robert S. Bobrow
The Journal of the American Board of Family Practice March 2005, 18 (2) 147-149; DOI: https://doi.org/10.3122/jabfm.18.2.147
Robert S. Bobrow
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. ↵
    Locke CF and Evans NC. Evaluating idiopathic venous thromboembolism: what is necessary, what is not. J Fam Pract 2003; 52: 770–6.
    OpenUrlPubMed
  2. ↵
    Ridker PM, Militich JP, Hennekens CH, Buring JE. Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening. JAMA 1997; 277: 1305–7.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    Koster T, Blann AD, Briet E, Vandenbroucke JP, Rosendaal FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet 1995; 345: 152–5.
    OpenUrlCrossRefPubMedWeb of Science
  4. ↵
    Kraaijenhagen RA, in’t Anker PS, Koopman MM, et al. High plasma concentration of factor VIIIc is a major risk factor for venous thromboembolism. Thromb Haemost 2000; 83: 5–9.
    OpenUrlPubMedWeb of Science
  5. ↵
    Kyrle PA, Minar E, Hirschl M, et al. High plasma levels of factor VIII and risk of recurrent thromboembolism. N Engl J Med 2000; 343: 457–62.
    OpenUrlCrossRefPubMedWeb of Science
  6. ↵
    O’Donnell J, Mumford AD, Manning RA, Laffan M. Elevation of FVIII: C in venous thromboembolism is persistent and independent of the acute phase reaction. Thromb Haemost 2000; 83: 10–3.
    OpenUrlPubMedWeb of Science
  7. O’Donnell J, Tuddenham EG, Manning R, Kemball-Cook G, Johnson D, Laffan M. High prevalence of elevated factor VIII levels in patients referred for thrombophilia screening: role of increased synthesis and relationship to the acute phase reaction. Thromb Haemost 1997; 77: 825–8.
    OpenUrlPubMedWeb of Science
  8. ↵
    Kamphuisen PW, Eikenboom JC, Vos HL, et al. Increased levels of factor VIII and fibrinogen in patients with venous thromboembolism are not caused by acute phase reactions. Thromb Haemost 1999; 81: 680–3.
    OpenUrlPubMedWeb of Science
  9. ↵
    Asherson RA. Antiphospholipid antibodies and syndromes. In: Systemic lupus erythematosus, 2nd ed (Lahita RG, editor). New York: Churchill Livingstone; 1992. p. 587–635.
  10. ↵
    Levine JS, Branch DW, Rauch J. Antiphospholipid antibody syndrome. N Engl J Med 2002; 346: 752–63.
    OpenUrl
  11. ↵
    Kim V, Spandorfer J. Epidemiology of venous thromboembolic disease. Emerg Med Clin North Am 2001; 19: 839–59.
    OpenUrlCrossRefPubMed
  12. ↵
    Goldenberg NA, Knapp-Clevenger R, Manco-Johnson MJ. Elevated plasma factor VIII and d-dimer levels as predictors of poor outcomes of thrombosis in children. N Engl J Med 2004; 351: 1081–8.
    OpenUrlCrossRefPubMedWeb of Science
  13. ↵
    Ridker PM. Inherited risk factors for venous thromboembolism: implications for clinical practice. Clin Cornerstone 2002; 4: 18–30.
    OpenUrlPubMed
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family Practice: 18 (2)
The Journal of the American Board of Family Practice
Vol. 18, Issue 2
1 Mar 2005
  • Table of Contents
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Excess Factor VIII: A Common Cause of Hypercoagulability
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
2 + 2 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Excess Factor VIII: A Common Cause of Hypercoagulability
Robert S. Bobrow
The Journal of the American Board of Family Practice Mar 2005, 18 (2) 147-149; DOI: 10.3122/jabfm.18.2.147

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Excess Factor VIII: A Common Cause of Hypercoagulability
Robert S. Bobrow
The Journal of the American Board of Family Practice Mar 2005, 18 (2) 147-149; DOI: 10.3122/jabfm.18.2.147
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Case 1
    • Case 2
    • Case 3
    • Discussion
    • Conclusion
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Pulmonary embolism in a British soldier: could this have been prevented?
  • Excess Factor VIII and Hypercoagulability
  • Google Scholar

More in this TOC Section

  • Factors Influencing Changing Scopes of Practice Among Contemporary Graduates of the Nation’s Largest Family Medicine Residency
  • Clusters of Health-Related Social Needs Among Adult Primary Care Patients
  • Patient Perspectives on Delayed Specialty Follow-Up After a Primary Care Visit
Show more Brief Reports

Similar Articles

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2025 American Board of Family Medicine

Powered by HighWire