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Research ArticleOriginal Research

Missed Opportunities for HIV Prevention in a Large County Safety Net Health System

Melanie G. Lopez, Kristin S. Alvarez, Michael Harms, Margaret Smith, Emily Levy Kamugisha, Elizabeth Mayfield Arnold and Helen L. King
The Journal of the American Board of Family Medicine March 2024, 37 (2) 261-269; DOI: https://doi.org/10.3122/jabfm.2023.230297R2
Melanie G. Lopez
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
BS
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Kristin S. Alvarez
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
PharmD, BCPS
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Michael Harms
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
MSBA
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Margaret Smith
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
PhD
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Emily Levy Kamugisha
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
MD
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Elizabeth Mayfield Arnold
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
PhD, LCSW
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Helen L. King
From the University of Texas Southwestern Medical Center (MGL); Parkland Health, Center of Innovation and Value, University of Texas Southwestern Medical Center (KSA, MH); Department of Family and Community Medicine, University of Texas Southwestern Medical Center (MS, ELK); College of Medicine, Department of Psychiatry, University of Kentucky (EMA); Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center (HLK).
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Article Figures & Data

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    Figure 1.

    Adjusted Odds Ratio of missed opportunity for counseling on PrEP or Condom Use or PrEP prescribing based on Characteristics. Abbreviation: PrEP, pre-exposure prophylaxis.

Tables

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    Table 1.

    Demographic Characteristics of Patients Diagnosed with HIV Who Had Prior Health System Interactions by Site of Healthcare Interaction

    Demographic CharacteristicsTotal Sample (n = 454) N (%) or Mean (SD)Ambulatory Care Received* (n = 353) N (%) or Mean (SD)Emergency-Care Only† (n = 101) N (%) or Mean (SD)P-Value
    Age at diagnosis38.6 (12.9)39.3 (12.8)36.1 (13.0)0.014
     < 30, n (%)130 (28.6)91 (25.8)39 (38.6)0.017
     ≥ 30, n (%)324 (71.4)262 (74.2)62 (61.4)
    Number of healthcare visits
     Total healthcare visits11.4 (15.8)13.3 (16.8)4.7 (8.6)<0.01
     ED visits3.2 (5.4)2.9 (4.6)4.2 (7.5)<0.01
     Inpatient admissions0.5 (1.0)0.6 (1.1)0.3 (0.68)<0.01
     Ambulatory visits7.8 (14.0)10 (15.1)–N/A
    Ethnicity/Race0.544
     Hispanic147 (32.4)111 (31.4)36 (35.6)
     Non-Hispanic – Black251 (55.3)199 (56.4)52 (51.5)
     Non-Hispanic – White52 (11.5)39 (11.0)13 (12.9)
     – Other/Unknown4 (0.9)4 (1.1)0 (0)
    Sex assigned at birth0.008
     Female170 (37.4)144 (40.8)26 (25.7)
     Male284 (62.6)209 (59.2)75 (74.3)
    Gender Identity0.49
     Cisgender309 (68.1)246 (69.7)63 (62.4)
     Transgender13 (2.9)10 (2.8)3 (3.0)
     Nonbinary1 (0.2)1 (0.3)0 (0)
     Unknown131 (28.9)96 (27.2)35 (34.7)
    Sexual Relationships0.28
     Heterosexual only270 (59.5)216 (61.2)54 (53.5)
     Same sex partners‡155 (34.1)117 (33.1)38 (37.6)
     Unknown29 (6.4)20 (5.7)9 (8.9)
    STI screen completed§§23 (5.1)21 (5.9)2 (2.0)0.178
    Year of HIV diagnosis0.609
     201536 (7.9)32 (9.1)4 (3.96)
     201633 (7.3)25 (7.1)8 (7.9)
     201775 (16.5)58 (16.4)17 (16.8)
     201886 (18.9)67 (19.0)19 (18.8)
     201996 (21.1)77 (21.8)19 (18.8)
     202076 (16.7)55 (15.6)21 (20.8)
     2021‖52 (11.5)39 (11.0)13 (12.9)
    Encounter after PrEP added to pharmacy formulary224 (49.3)171 (48.4)53 (52.5)0.547
    • * Ambulatory Care Received included patients who had at least 1 ambulatory visit and could include patients who also engaged with the emergency care setting.

    • † Emergency Care Only included patients who only interacted with the Emergency Department, Urgent Care Clinic, and/or Inpatient Settings.

    • ‡ Same sex partners included patients that have both male and female partners and those who exclusively had same sex partners.

    • §Defined as having all 3 of the following STI tests: Gonorrhea, Chlamydia, and Syphilis test.

    • ‖Ending 6/30/2021.

    • Abbreviation: SD, standard deviation.

    • View popup
    Table 2.

    Patients with Indications for HIV PrEP Identified Before HIV Diagnosis by Site of Healthcare Interaction, n = 454

    Indication for HIV PrEP*Total Patients, n (%), n = 454Ambulatory Care Received, n (%), n = 353Emergency-Care Only, n (%), n = 101P-Value
    One or more PrEP Indication166 (36.6)139 (39.4)27 (26.7)0.027
    IV Drug Use82 (18.1)65 (18.7)17 (17.3)0.878
    Bacterial STI in last 5 years (one or more)62 (13.7)56 (15.9)6 (5.9)0.017
    Type of Bacterial STI
     Gonorrhea25 (5.5)21 (5.9)4 (4.0)0.599
     Chlamydia21 (4.6)20 (5.7)1 (1.0)0.088
     Syphilis10 (2.2)10 (2.8)0 (0)0.185
    Self-reported STI†21 (4.6)20 (5.7)1 (1.0)0.088
    Patient requested STI screen‡8 (1.8)7 (2.0)1 (1.0)0.81
    Condomless Sex0.013
     Yes63 (13.9)57 (16.1)6 (5.9)
     No43 (9.5)36 (10.2)7 (6.9)
     Unknown348 (76.7)260 (73.7)88 (87.1)
    • ↵*Indications for HIV PrEP are those identified from documentation in the EHR for 5 years before the date of HIV diagnosis.

    • ↵†Results not available in the EHR.

    • ↵‡‡Patient requested STI screening before HIV diagnosis due to a known or suspected exposure.

    • Abbreviations: HIV, human immunodeficiency virus; STI, sexually transmitted infections.

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The Journal of the American Board of Family     Medicine: 37 (2)
The Journal of the American Board of Family Medicine
Vol. 37, Issue 2
March-April 2024
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Missed Opportunities for HIV Prevention in a Large County Safety Net Health System
Melanie G. Lopez, Kristin S. Alvarez, Michael Harms, Margaret Smith, Emily Levy Kamugisha, Elizabeth Mayfield Arnold, Helen L. King
The Journal of the American Board of Family Medicine Mar 2024, 37 (2) 261-269; DOI: 10.3122/jabfm.2023.230297R2

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Missed Opportunities for HIV Prevention in a Large County Safety Net Health System
Melanie G. Lopez, Kristin S. Alvarez, Michael Harms, Margaret Smith, Emily Levy Kamugisha, Elizabeth Mayfield Arnold, Helen L. King
The Journal of the American Board of Family Medicine Mar 2024, 37 (2) 261-269; DOI: 10.3122/jabfm.2023.230297R2
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