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Research ArticleOriginal Research

The Prevalence of Periodontitis Among US Adults with Multimorbidity Using NHANES Data 2011–2014

Marie Claire O’Dwyer, Allison Furgal, Wendy Furst, Manasi Ramakrishnan, Nicoll Capizzano, Ananda Sen and Michael Klinkman
The Journal of the American Board of Family Medicine April 2023, 36 (2) 313-324; DOI: https://doi.org/10.3122/jabfm.2022.220207R1
Marie Claire O’Dwyer
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
MB, BCh, BAO, MPH
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Allison Furgal
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
PhD
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Wendy Furst
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
MA
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Manasi Ramakrishnan
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
MD
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Nicoll Capizzano
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
MD
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Ananda Sen
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
PhD
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Michael Klinkman
From the Department of Family Medicine, University of Michigan Medical School, Ann Arbor, MI (MCO, AF, WF, MR, NC, AS, MK); Department of Biostatistics, School of Public Health, University of Michigan (AF, AS).
MD
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Article Figures & Data

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  • Figure 1.
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    Figure 1.

    Schematic representation of differences in multimorbidity prevalence of individuals excluded from periodontal examination.

Tables

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    Table 1.

    Selected Covariates by Multimorbidity (in Weighted Percentages)* in Observed Data

    No multimorbidityMultimorbidity
    CovariateMean (SD)Mean (SD)P±
    Age, continuous45.4 (0.3)± ±55.9 (0.3)<0.0001
    Sex (male)52.245.6<0.0001
    Race/ethnicity
    Mexican American10.26.4<0.0001
    Other Hispanic6.25.1
    Non-Hispanic White63.771.6
    Non-Hispanic Black10.011.0
    Non-Hispanic Asian7.83.3
    Other2.02.7
    Education<0.0001
    <9th grade5.04.9
    9th to 11th grade8.99.9
    High school diploma or equivalent19.421.3
    Some college/associate’s degree26.733.9
    Bachelor’s degree or higher40.030.1
    Marital status<0.0001
    Married65.560.4
    Widowed2.37.6
    Divorced10.714.4
    Separated2.52.7
    Never married11.79.7
    Living with partner7.35.2
    Monthly household income
    Low ($0–$1649)15.920.2<0.0001
    Middle ($1650–$4599)34.339.2
    High (≥$4600)49.840.6
    Length of time since last dentist visit0.012
    0 to 6 months49.253.2
    6 months to 1 year14.013.8
    1 to 2 years12.110.5
    2 to 3 years5.96.6
    3 to 5 y ears6.25.9
    5+ years11.39.5
    Never visited dentist1.20.5
    Needed dental in last year and didn’t get it (yes)15.018.60.006
    Current smoker<0.0001
    Every day37.230.6
    Some days8.85.5
    Not at all54.063.9
    Averages 2+ drinks per day (yes)33.329.60.003
    Number of prescriptions
    0–182.033.9<0.0001
    2–415.939.0
    5–102.124.1
    ≥110.03.1
    Health insurance coverage (yes)76.687.5<0.0001
    General health condition<0.0001
    Excellent17.76.2
    Very good38.727.8
    Good34.843.3
    Fair8.318.8
    Poor0.53.9
    • Abbreviation: SD, standard deviation.

    • ↵* Numbers are weighted column percentages.

    • ↵± P-value is for chi-sq test for difference by MM/no MM; for continous age is from a t-test.

    • ↵±± Mean (Standard Deviation).

    • View popup
    Table 2.

    Selected Covariates by Periodontitis (in Weighted Percentages)* in Observed Data

    No PeriodontitisPeriodontitis
    CovariateMean (SD)Mean (SD)P±
    Age, continuous48.7 (0.4)±±54.5 (0.4)<0.0001
    Sex (male)42.657.8<0.0001
    Race/ethnicity<0.0001
    Mexican American5.911.5
    Other Hispanic4.86.8
    Non-Hispanic White74.358.5
    Non-Hispanic Black7.714.7
    Non-Hispanic Asian5.05.9
    Other2.22.6
    Education<0.0001
    <9th grade2.58.6
    9th to 11th grade6.214.3
    High school diploma or equivalent16.326.7
    Some college/associate’s degree30.830.2
    Bachelor’s degree or higher44.120.3
    Marital status<0.0001
    Married68.254.4
    Widowed3.77.5
    Divorced11.214.9
    Separated1.73.9
    Never married9.911.8
    Living with partner5.37.5
    Monthly household income<0.0001
    Low ($0–$1649)13.126.1
    Middle ($1650–$4599)31.245.8
    High (≥$4600)55.728.1
    Length of time since last dentist visit<0.0001
    0 to 6 months59.539.1
    6 months to 1 year14.413.2
    1 to 2 years10.113.1
    2 to 3 years5.67.3
    3 to 5 y ears4.78.0
    5+ years5.517.6
    Never visited dentist0.31.7
    Needed dental in last year and didn’t get it (yes)11.425.4<0.0001
    Current smoker<0.0001
    Every day24.841.6
    Some days6.17.5
    Not at all69.150.9
    Averages 2+ drinks per day (yes)25.641.0<0.0001
    Number of prescriptions<0.0001
    0–157.953.2
    2–429.326.9
    5–1011.717.3
    ≥111.12.5
    Health insurance coverage (yes)87.574.9<0.0001
    General health condition<0.0001
    Excellent13.58.2
    Very good36.327.4
    Good37.642.2
    Fair11.018.8
    Poor1.63.5
    • Abbreviation: SD, standard deviation.

    • ↵* Numbers are weighted column percentages.

    • ↵± P-value is for chi-sq test for difference by MM/no MM; for continous age is from a t-test.

    • ↵±± Mean (Standard Deviation).

    • View popup
    Table 3.

    Weighted Percentages of Chronic Conditions by Periodontitis Status

    Chronic conditionPeriodontitisWeighted %Unadjusted PAdjusted P
    HypertensionNo37.2<0.00010.325
    Yes46.8
    ArthritisNo38.60.0020.615
    Yes43.8
    Cardiovascular diseaseNo39.1<0.0010.020
    Yes61.9
    Heart failureNo39.3<0.0010.001
    Yes70.1
    StrokeNo39.60.0020.730
    Yes56.5
    DiabetesNo37.9<0.001<0.001
    Yes57.7
    Kidney disease/failureNo39.50.0030.163
    Yes55.1
    ObesityNo38.40.0040.093
    Yes42.5
    Depression or anxietyNo39.30.0130.928
    Yes47.9
    • Notes: Unadjusted P values are from PROC SURVEYFREQ in SAS. Adjusted P values are from weighted logistic regression models on the imputed data with the binary chronic condition variable as a predictor and adjusted for age, gender, race/ethnicity, education, income, health insurance status, smoking, and alcohol use.

    • View popup
    Table 4.

    Logistic Regression Results From Weighted Logistic Models on 25 Imputed Datasets

    ParameterOR95% CI
    Basic MM
    No (reference)
    Yes0.980.911.06
    Age   
    30 to 35 years
    40 to 49 years0.720.630.82
    50 to 64 years1.361.181.57
    ≥65 years2.802.403.27
    Sex   
    Female (reference)
    Male1.441.361.51
    Race/ethnicity   
    Non-Hispanic White (reference)
    Mexican American1.180.991.42
    Non-Hispanic Asian1.491.191.88
    Non-Hispanic Black1.301.061.61
    Other Hispanic0.950.791.13
    Other race0.750.471.18
    Education   
    College degree or higher (reference)
    <9th grade1.521.211.90
    9th to 11th grade1.331.071.65
    High school diploma or equivalent1.171.051.29
    Some college/associate’s degree0.820.740.90
    Income   
    High (reference)
    Low1.251.101.43
    Middle1.221.081.39
    Health insurance status   
    Yes (reference)
    No1.291.201.39
    Smoking   
    Not at all (reference)
    Every day1.341.151.56
    Some days1.060.841.34
    Alcohol: 2 or more drinks/day   
    No (reference)
    Yes1.181.071.31
    • Notes: Results from each imputed dataset combined using PROC MIANALYZE, odds ratios (ORs), with 95% confidence intervals (CIs) and P values. Sensitivity analysis: Model results assuming all missing smoking is “Everyday” and all missing alcohol is “Yes”.

    • Abbreviations: MM, multimorbidity; CI, confidence interval.

  • Appendix 1. Qualifying Conditions From Fortin et al. and Corresponding National Health and Nutrition Examination Survey (NHANES) Categories

    Chronic conditionNHANES
    1.Hypertension (high blood pressure)BPQ020
    2.Depression or anxietyDPQ010- DPQ090 PHQ9 score calulated
    3.Chronic musculoskeletal conditions causing pain or limitationNo corresponding data
    4.Arthritis and/or rheumatoid arthritisMCQ160a
    5.OsteoporosisOSQ060
    6.Asthma, chronic obstructive pulmonary disease (COPD), or chronic bronchitisMCQ010, MCQ0160o, MCQ0160k
    7.Cardiovascular disease (angina, myocardial infarction, atrial fibrillation, poor circulation in the lower limbs)MCQ160d, MCQ160e,
    8.Heart failure (including valve problems or replacement)MCQ160b
    9.Stroke and transient ischemic attackMCQ160f
    10.Stomach problem (reflux, heartburn, or gastric ulcer)No corresponding data
    11.Colon problem (irritable bowel, Crohn’s disease, ulcerative colitis, diverticulosis)No corresponding data
    12.Chronic hepatitisHEQ010, HEQ030
    13.DiabetesDIQ010
    14.Thyroid disorderMCQ170m
    15.Any cancer in the previous 5 years (including melanoma, but excluding other skin cancers)MCQ220
    16.Kidney disease or failureKIQ022, KIQ025
    17.Chronic urinary problemNo corresponding data
    18.Dementia or Alzheimer’s diseaseMCQ084
    19.Hyperlipidemia (high cholesterol)BPQ080
    20.Obesity (diagnosed through the calculation of the body mass index)BMXBMI
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The Journal of the American Board of Family     Medicine: 36 (2)
The Journal of the American Board of Family Medicine
Vol. 36, Issue 2
March/April 2023
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The Prevalence of Periodontitis Among US Adults with Multimorbidity Using NHANES Data 2011–2014
Marie Claire O’Dwyer, Allison Furgal, Wendy Furst, Manasi Ramakrishnan, Nicoll Capizzano, Ananda Sen, Michael Klinkman
The Journal of the American Board of Family Medicine Apr 2023, 36 (2) 313-324; DOI: 10.3122/jabfm.2022.220207R1

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The Prevalence of Periodontitis Among US Adults with Multimorbidity Using NHANES Data 2011–2014
Marie Claire O’Dwyer, Allison Furgal, Wendy Furst, Manasi Ramakrishnan, Nicoll Capizzano, Ananda Sen, Michael Klinkman
The Journal of the American Board of Family Medicine Apr 2023, 36 (2) 313-324; DOI: 10.3122/jabfm.2022.220207R1
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  • Cross-Sectional Studies
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