Metformin Prescription Rates for Patients with Prediabetes

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Figure 1.
Study flow diagram. Abbreviations: FPG, fasting plasma glucose; HbA1c, glycohemoglobin A1c.
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Figure 2.
Density plots for glycohemoglobin (HA1c) laboratory results in prediabetes range, with American Diabetes Association (ADA) criteria. *Body mass index (BMI) panel includes only patients with most recent BMI measurement ± 365 days from time of first glycohemoglobin A1c (HbA1c) laboratory result.
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Figure 3.
Density plots for Fasting Plasma Glucose (FPG) laboratory results in prediabetes range, with American Diabetes Association (ADA) criteria. *Body mass index (BMI) panel includes only patients with most recent BMI measurement ± 365 days from time of first FPG laboratory result.

Table 1.

Characteristics of Patients with at Least One Laboratory Result in Prediabetes Range

↵* Patients with prediabetes who recorded a diabetes diagnosis within one or three years of initial laboratory result, based on ICD-10 code.

Table 2.

Proportion of Patients with Prediabetes Receiving a Metformin Prescription, Based on American Diabetes Association (ADA) Criteria (n = 53,551)

Population	No Diabetes Diagnosis < 1 Year^*	Metformin Prescription < 1 Year (%)	No Diabetes Diagnosis < 3 Years^*	Metformin Prescription < 3 Years (%)
Total population with prediabetes	50,782	1,214 (2.4)	46,283	1,901 (4.1)
Age < 60 years	26,553	632 (2.4)	24,200	948 (3.9)
BMI ≥ 35 kg/m^{2^†}	4,609	481 (10.4)	4,065	569 (14.0)
Age < 60 years & BMI ≥ 35 kg/m^{2^†}	3,024	318 (10.5)	2,660	368 (13.8)

↵* Indicates number of patients with a type 2 diabetes diagnosis in subsequent one or three years from date of first laboratory result in prediabetes range.
↵† BMI within ± 365 days of first laboratory result in prediabetes range.
Abbreviation: BMI, body mass index.