Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Abstracts In Press
    • Archives
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Abstracts In Press
    • Archives
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM on Bluesky
  • JABFM On Facebook
  • JABFM On Twitter
  • JABFM On YouTube
Research ArticleResearch Letter

Methotrexate Toxicity from Unintentional Dosing Errors: Calls to a Poison Center and Death Descriptions

John A. Thompson, Jennifer S. Love and Robert G. Hendrickson
The Journal of the American Board of Family Medicine November 2021, 34 (6) 1246-1248; DOI: https://doi.org/10.3122/jabfm.2021.06.210120
John A. Thompson
From Oregon Poison Center, Portland, OR (JAT, JSL, RGH); Department of Emergency Medicine, Oregon Health & Science University, Portland (JAT, JSL, RGH).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jennifer S. Love
From Oregon Poison Center, Portland, OR (JAT, JSL, RGH); Department of Emergency Medicine, Oregon Health & Science University, Portland (JAT, JSL, RGH).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert G. Hendrickson
From Oregon Poison Center, Portland, OR (JAT, JSL, RGH); Department of Emergency Medicine, Oregon Health & Science University, Portland (JAT, JSL, RGH).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. 1.↵
    1. Singh JA,
    2. Furst DE,
    3. Bharat A,
    4. et al
    . 2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken) 2012;64:625–39.
    OpenUrl
  2. 2.↵
    1. Radmanesh M,
    2. Rafiei B,
    3. Moosavi ZB,
    4. Sina N
    . Weekly vs. daily administration of oral methotrexate (MTX) for generalized plaque psoriasis: a randomized controlled clinical trial. Int J Dermatol 2011;50:1291–3.
    OpenUrlPubMed
  3. 3.↵
    Cumberland Pharmaceuticals Inc. Reditrex (methotrexate) [package insert]. U.S. Food and Drug Administration website. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210737s000lbl.pdf. Accessed May 11, 2021.
  4. 4.↵
    1. Bebarta VS,
    2. Hensley MD,
    3. Borys DJ
    . Acute methotrexate ingestions in adults: a report of serious clinical effects and treatments. J Toxicol 2014;2014:214574.
    OpenUrl
  5. 5.↵
    1. Lovecchio F,
    2. Katz K,
    3. Watts D,
    4. Wood I
    . Four-year experience with methotrexate exposures. J Med Toxicol 2008;4:149–50.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Gummin DD,
    2. Mowry JB,
    3. Beuhler MC,
    4. et al
    . 2019 annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th annual report. Clin Toxicol (Phila) 2020;58:1360–541.
    OpenUrl
  7. 7.↵
    1. Hays H,
    2. Beuhler MC,
    3. Spiller HA,
    4. et al
    . Evaluation of toxicity after acute accidental methotrexate ingestions in children under 6 years old: a 16-year multi-center review. Clin Toxicol (Phila) 2018;56:120–5.
    OpenUrl
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family   Medicine: 34 (6)
The Journal of the American Board of Family Medicine
Vol. 34, Issue 6
November/December 2021
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Methotrexate Toxicity from Unintentional Dosing Errors: Calls to a Poison Center and Death Descriptions
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
3 + 11 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Methotrexate Toxicity from Unintentional Dosing Errors: Calls to a Poison Center and Death Descriptions
John A. Thompson, Jennifer S. Love, Robert G. Hendrickson
The Journal of the American Board of Family Medicine Nov 2021, 34 (6) 1246-1248; DOI: 10.3122/jabfm.2021.06.210120

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Methotrexate Toxicity from Unintentional Dosing Errors: Calls to a Poison Center and Death Descriptions
John A. Thompson, Jennifer S. Love, Robert G. Hendrickson
The Journal of the American Board of Family Medicine Nov 2021, 34 (6) 1246-1248; DOI: 10.3122/jabfm.2021.06.210120
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Notes
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Research on the Issues Family Physicians Face Today: Controlled Substances, COVID-19, Hypertension, and "Slow Medicine," Among Many More Topics
  • Google Scholar

More in this TOC Section

  • Timing of Certification Stage Completion Associated with Subsequent Certification Exam Outcomes Among Board-Certified Family Physicians
  • Interpersonal Continuity of Care May Help Delay Progression to Type 2 Diabetes
  • Impact of Point of Care Hemoglobin A1c Testing on Time to Therapeutic Intervention
Show more Research Letters

Similar Articles

Keywords

  • Drug-Related Side Effects and Adverse Reactions
  • Leucovorin
  • Medical Errors
  • Methotrexate
  • Poison Center
  • Retrospective Studies

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2025 American Board of Family Medicine

Powered by HighWire