Clinicians' Perspectives on Barriers and Enablers of Optimal Prescribing in Patients with Dementia and Coexisting Conditions

References

1. 1.↵
   Alzheimer's Association. 2016 Alzheimer's disease facts and figures. Alzheimers Dement. 2016;12:459–509.

   OpenUrlCrossRefPubMed
2. 2.↵
   1. Brauner DJ,
   2. Muir JC,
   3. Sachs GA

   . Treating nondementia illnesses in patients with dementia. JAMA 2000;283:3230–5.

   OpenUrlCrossRefPubMedWeb of Science
3. 3.↵
   1. Lin PJ,
   2. Zhong Y,
   3. Fillit HM,
   4. Chen E,
   5. Neumann PJ

   . Medicare expenditures of individuals with Alzheimer's disease and related dementias or mild cognitive impairment before and after diagnosis. J Am Geriatr Soc 2016;64:1549–57.

   OpenUrl
4. 4.↵
   1. Reeve E,
   2. Bell JS,
   3. Hilmer SN

   . Barriers to optimising prescribing and deprescribing in older adults with dementia: a narrative review. Curr Clin Pharmacol 2015;10:168–77.

   OpenUrlCrossRefPubMed
5. 5.↵
   1. Lau DT,
   2. Mercaldo ND,
   3. Harris AT,
   4. Trittschuh E,
   5. Shega J,
   6. Weintraub S

   . Polypharmacy and potentially inappropriate medication use among community-dwelling elders with dementia. Alzheimer Dis Assoc Disord 2010;24:56–63.

   OpenUrlCrossRefPubMed
6. 6.↵
   1. Johnell K

   . Inappropriate drug use in people with cognitive impairment and dementia: a systematic review. Curr Clin Pharmacol 2015;10:178–84.

   OpenUrlCrossRefPubMed
7. 7.↵
   1. Palinkas LA,
   2. Horwitz SM,
   3. Green CA,
   4. Wisdom JP,
   5. Duan N,
   6. Hoagwood K

   . Purposeful sampling for qualitative data collection and analysis in mixed method implementation research. Adm Policy Ment Health 2015;42:533–44.

   OpenUrlCrossRefPubMed
8. 8.↵
   1. Strauss AL

   1. Glaser BG

   . The discovery of grounded theory: strategies for qualitative research. In: Strauss AL, ed. Chicago (IL): Aldine Pub. Co.; 1967.
9. 9.↵
   1. Strauss AL

   1. Corbin JM

   . Basics of qualitative research techniques and procedures for developing grounded theory. In: Strauss AL, ed. Los Angeles (CA), SAGE; 2008.
10. 10.↵
    1. Kouladjian L,
    2. Gnjidic D,
    3. Reeve E,
    4. Chen TF,
    5. Hilmer SN

    . Health care practitioners' perspectives on deprescribing anticholinergic and sedative medications in older adults. Ann Pharmacother 2016;50:625–36.

    OpenUrlCrossRefPubMed
11. 11.↵
    1. Ailabouni NJ,
    2. Nishtala PS,
    3. Mangin D,
    4. Tordoff JM

    . General practitioners' insight into deprescribing for the multimorbid older individual: a qualitative study. Int J Clin Pract 2016;70:261–76.

    OpenUrlPubMed
12. 12.↵
    1. Anderson K,
    2. Stowasser D,
    3. Freeman C,
    4. Scott I

    . Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open 2014;4:e006544.

    OpenUrlAbstract/FREE Full Text
13. 13.↵
    1. Cook JM,
    2. Marshall R,
    3. Masci C,
    4. Coyne JC

    . Physicians' perspectives on prescribing benzodiazepines for older adults: a qualitative study. J Gen Intern Med 2007;22:303–7.

    OpenUrlCrossRefPubMedWeb of Science
14. 14.↵
    1. Croskerry P

    . The importance of cognitive errors in diagnosis and strategies to minimize them. Acad Med 2003;78:775–80.

    OpenUrlCrossRefPubMedWeb of Science
15. 15.↵
    1. Gurwitz JH

    . The physics of geriatric pharmacotherapy: overcoming therapeutic inertia and momentum. Am J Med 2012;125:523–4.

    OpenUrlCrossRefPubMed
16. 16.↵
    American Diabetes Association. 11. Older adults: standards of med care in diabetes-2018. Diabetes Care. 2018;41:S119–S25.

    OpenUrlAbstract/FREE Full Text
17. 17.↵
    1. Schuling J,
    2. Gebben H,
    3. Veehof LJ,
    4. Haaijer-Ruskamp FM

    . Deprescribing medication in very elderly patients with multimorbidity: the view of Dutch GPs. A qualitative study. BMC Fam Pract 2012;13:56.

    OpenUrlCrossRefPubMed
18. 18.↵
    1. Palagyi A,
    2. Keay L,
    3. Harper J,
    4. Potter J,
    5. Lindley RI

    . Barricades and brickwalls–a qualitative study exploring perceptions of medication use and deprescribing in long-term care. BMC Geriatr 2016;16:15.

    OpenUrl
19. 19.↵
    1. Turner JP,
    2. Edwards S,
    3. Stanners M,
    4. Shakib S,
    5. Bell JS

    . What factors are important for deprescribing in Australian long-term care facilities? Perspectives of residents and health professionals. BMJ Open 2016;6:e009781.

    OpenUrlAbstract/FREE Full Text
20. 20.↵
    1. Holmes HM,
    2. Hayley D,
    3. Alexander G,
    4. Sachs GA

    . Reconsidering medication appropriateness for patients late in life. Arch Intern Med 2006;166:605–9.

    OpenUrlCrossRefPubMedWeb of Science
21. 21.↵
    1. Narayan SW,
    2. Nishtala PS

    . Discontinuation of preventive medicines in older people with limited life expectancy: a systematic review. Drugs Aging 2017;34:767–76.

    OpenUrl
22. 22.↵
    1. Parsons C,
    2. Hughes CM,
    3. Passmore AP,
    4. Lapane KL

    . Withholding, discontinuing and withdrawing medications in dementia patients at the end of life: a neglected problem in the disadvantaged dying? Drugs Aging 2010;27:435–49.

    OpenUrlCrossRefPubMedWeb of Science
23. 23.↵
    1. Zulman DM,
    2. Sussman JB,
    3. Chen X,
    4. Cigolle CT,
    5. Blaum CS,
    6. Hayward RA

    . Examining the evidence: a systematic review of the inclusion and analysis of older adults in randomized controlled trials. J Gen Intern Med 2011;26:783–90.

    OpenUrlCrossRefPubMed
24. 24.↵
    1. Zanetti O,
    2. Solerte SB,
    3. Cantoni F

    . Life expectancy in Alzheimer's disease (AD). Arch Gerontol Geriatr 2009;49:237–243.

    OpenUrlPubMedWeb of Science
25. 25.↵
    1. Boyd CM,
    2. Darer J,
    3. Boult C,
    4. Fried LP,
    5. Boult L,
    6. Wu AW

    . Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA 2005;294:716–24.

    OpenUrlCrossRefPubMedWeb of Science
26. 26.↵
    1. Whelton PK,
    2. Carey RM,
    3. Aronow WS,
    4. et al

    . 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults. A report of the american college of cardiology/american heart association task force on clinical practice guidelines. Hypertension 2018;71:e127–e248.

    OpenUrl
27. 27.↵
    1. Poudel A,
    2. Yates P,
    3. Rowett D,
    4. Nissen LM

    . Use of preventive medication in patients with limited life expectancy: a systematic review. J Pain Symptom Manage 2017;53:1097–1110.e1091.

    OpenUrl
28. 28.↵
    1. Page AT,
    2. Clifford RM,
    3. Potter K,
    4. et al

    . Exploring the enablers and barriers to implementing the Medication Appropriateness Tool for Comorbid Health conditions during Dementia (MATCH-D) criteria in Australia: a qualitative study. BMJ Open 2017;7:e017906.

    OpenUrlAbstract/FREE Full Text
29. 29.↵
    1. Smith F,
    2. Grijseels MS,
    3. Ryan P,
    4. Tobiansky R

    . Assisting people with dementia with their medicines: experiences of family carers. Int J Pharm Pract 2015;23:44–51.

    OpenUrl
30. 30.↵
    1. Wolff JL,
    2. Spillman BC,
    3. Freedman VA,
    4. Kasper JD

    . A national profile of family and unpaid caregivers who assist older adults with health care activities. JAMA Intern Med 2016;176:372–9.

    OpenUrl
31. 31.↵
    1. Kasper JD,
    2. Freedman VA,
    3. Spillman BC,
    4. Wolff JL

    . The disproportionate impact of dementia on family and unpaid caregiving to older adults. Health Aff (Millwood) 2015;34:1642–9.

    OpenUrlAbstract/FREE Full Text
32. 32.↵
    1. Reinhard SC,
    2. Levine C,
    3. Samis S

    . Home alone: family caregivers providing complex chronic care. Washington, D.C., AARP; 2012.
33. 33.↵
    1. Gitlin LN,
    2. Kales HC,
    3. Lyketsos CG

    . Nonpharmacologic management of behavioral symptoms in dementia. JAMA 2012;308:2020–9.

    OpenUrlCrossRefPubMedWeb of Science
34. 34.↵
    1. Callahan CM,
    2. Boustani MA,
    3. Unverzagt FW,
    4. et al

    . Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: a randomized controlled trial. JAMA 2006;295:2148–57.

    OpenUrlCrossRefPubMedWeb of Science
35. 35.↵
    1. Jennings LA,
    2. Tan Z,
    3. Wenger NS,
    4. et al

    . Quality of care provided by a comprehensive dementia care comanagement program. J Am Geriatr Soc 2016;64:1724–30.

    OpenUrl
36. 36.↵
    1. Bass DM,
    2. Judge KS,
    3. Snow AL,
    4. et al

    . Caregiver outcomes of partners in dementia care: effect of a care coordination program for veterans with dementia and their family members and friends. J Am Geriatr Soc 2013;61:1377–86.

    OpenUrlCrossRefPubMed
37. 37.↵
    1. Kerns JW,
    2. Winter JD,
    3. Winter KM,
    4. Kerns CC,
    5. Etz RS

    . Caregiver perspectives about using antipsychotics and other medications for symptoms of dementia. Gerontologist. 2018;58:e35–e45.

    OpenUrl
38. 38.↵
    1. Reeve E,
    2. Low LF,
    3. Hilmer SN

    . Beliefs and attitudes of older adults and carers about deprescribing of medications: a qualitative focus group study. Br J Gen Pract 2016;66:e552–560.

    OpenUrlAbstract/FREE Full Text
39. 39.↵
    1. Moen J,
    2. Bohm A,
    3. Tillenius T,
    4. Antonov K,
    5. Nilsson JL,
    6. Ring L

    . “I don't know how many of these [medicines] are necessary.” - a focus group study among elderly users of multiple medicines. Patient Educ Couns 2009;74:135–41.

    OpenUrlCrossRefPubMedWeb of Science
40. 40.↵
    1. Fagerlin A,
    2. Zikmund-Fisher BJ,
    3. Ubel PA

    . Helping patients decide: ten steps to better risk communication. J Natl Cancer Inst 2011;103:1436–43.

    OpenUrlCrossRefPubMedWeb of Science
41. 41.↵
    1. Farrell B,
    2. Black C,
    3. Thompson W,
    4. et al

    . Deprescribing antihyperglycemic agents in older persons: evidence-based clinical practice guideline. Can Fam Physician 2017;63:832–43.

    OpenUrlAbstract/FREE Full Text
42. 42.↵
    1. Jennings AA,
    2. Boyle S,
    3. Foley T

    . The development and evaluation of an online dementia resource for primary care based health professionals. Internet Interv 2018;11:47–52.

    OpenUrl
43. 43.↵
    1. Page AT,
    2. Potter K,
    3. Clifford R,
    4. McLachlan AJ,
    5. Etherton-Beer C

    . Medication appropriateness tool for co-morbid health conditions in dementia: consensus recommendations from a multidisciplinary expert panel. Intern Med J 2016;46:1189–97.

    OpenUrl
44. 44.↵
    1. Nagykaldi ZJ,
    2. Tange H,
    3. De Maeseneer J

    . Moving from problem-oriented to goal-directed health records. Ann Fam Med 2018;16:155–9.

    OpenUrlAbstract/FREE Full Text