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Research ArticleOriginal Research

Clinicians' Perspectives on Barriers and Enablers of Optimal Prescribing in Patients with Dementia and Coexisting Conditions

Ariel R. Green, Patricia Lee, Emily Reeve, Jennifer L. Wolff, Chi Chiung Grace Chen, Rachel Kruzan and Cynthia M. Boyd
The Journal of the American Board of Family Medicine May 2019, 32 (3) 383-391; DOI: https://doi.org/10.3122/jabfm.2019.03.180335
Ariel R. Green
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
MD, MPH
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Patricia Lee
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
BA
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Emily Reeve
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
PhD
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Jennifer L. Wolff
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
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Chi Chiung Grace Chen
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
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Rachel Kruzan
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
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Cynthia M. Boyd
From Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD (ARG, CMB); University of Illinois College of Medicine at Chicago, Chicago (PL); Kolling Institute of Medical Research, Northern Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia (ER); Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (JLW); Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine (CCGC); Johns Hopkins Community Physicians, Baltimore, MD (RK); Department of Health Policy and Management, Baltimore, Johns Hopkins University Bloomberg School of Public Health, MD (CMB).
MD, MPH
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Article Figures & Data

Tables

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    Table 1.

    Participant Characteristics

    CharacteristicValue
    Age, mean (SD) (years)46.6 (9)
    Race/ethnicity, n (%)
        White10 (48)
        African American0 (0)
        Asian9 (43)
        Hispanic0 (0)
        Other2 (10)
    Academic degree, n (%)
        MD18 (86)
        DO1 (5)
        CRNP2 (10)
    Specialty, n (%)*
        Family medicine6 (29)
        Internal medicine6 (29)
        Geriatric medicine3 (14)
        Urogynecology3 (14)
        Endocrinology3 (14)
        Cardiology3 (14)
    Clinic site, n (%)
        Urban8 (38)
        Suburban9 (43)
        Rural/suburban†4 (19)
    Years since completing clinical training, mean (SD)13.8 (10)
    No. of clinic sessions per week, mean (SD)‡7.3 (3)
    Proportion of patients with dementia in panel, n (%)§
        <10%13 (62)
        10% to 25%8 (38)
        26% to 75%0 (0)
        >75%0 (0)
    • SD, standard deviation.

    • ↵* Participants could select more than one response.

    • ↵† The clinic served a mix of rural and suburban populations.

    • ↵‡ One 4-hour session per week.

    • ↵§ As estimated by participant.

    • View popup
    Table 2.

    Clinician-Perceived Barriers to Optimizing Prescribing in Dementia

    SubthemeRepresentative Quotation
    Lack of dataNot only do I have to look at the evidence, but I also have to look at the whole patient…I can't just focus on the guidelines…So many of these decisions are subjective rather than objective. (primary care provider)
    Difficulty of assessing medication effects in an individual patientI would always do a little of the typical delirium check like, “Does a stone float?” I often ask them, “Do you see anything you think isn't there or do you hear anything you think isn't happening?” (primary care provider)
    Need to consider caregiver availability, knowledge, and skills in prescribing decisionsI have limited time with patients so I…really need to be selective about who I end up talking to about [behavioral strategies to treat incontinence]. If it's someone who's lucky to have someone even looking in on them once a day, then what's the point of talking to them about that? (urogynecologist)
    Perceptions of patient and caregiver beliefs and expectationsCaregivers worry about this decision means I gave up on mom or that I'm her executioner because I stopped that med. (primary care provider)
    Cognitive biasesI told the daughter, “I really don't see having this cholesterol lowering medicine.” It seemed like within maybe just 2 months, she went into the ER and she had a stroke. (primary care provider)
    System barriersMaybe it is my place, but I'm not very good at calling another specialist and saying, “I'm concerned about this…” I'm the generalist. I'm not the specialist. They know more than I do; this is their area. (primary care provider)
    • View popup
    Table 3.

    Language Used by Clinicians to Discuss Medications and Deprescribing with Patients and Caregivers

    SubthemeRepresentative Quotation
    Explicit mention of life expectancyI probably put it something like this: “Do you know that even if a person does not have any medical issues, dementia by itself can shorten your life expectancy? In your father or mother, the goal is to keep them comfortable. With medications there is risk and what are we trying to achieve?” (primary care provider)
    Focus on quality of lifeI broach it as a positive thing for the patient: “We're not harming them in any way [by stopping medicines], but we're trying to give them a better quality of life.” (cardiologist)
    Focus on long-term benefits of medication versus short-term harmsSomeone like yourself with a lot of other medical problems, with maybe heart problems, lung problems, memory problems, there probably is not a ton of benefit to us being very aggressive in controlling your diabetes…I can certainly get your blood sugars normal, but the problem is by doing that, I expose you to a lot of risks. (endocrinologist)
    Conditional or subjective languageI tell them the side effects of this medicine [bladder antimuscarinic] sometimes are a dry mouth. It might cause a little memory problem. (primary care clinician)
    Negative framingThere are all these medications that you could try [for incontinence] but they come with a significant risk of causing confusion. (primary care provider)
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The Journal of the American Board of Family     Medicine: 32 (3)
The Journal of the American Board of Family Medicine
Vol. 32, Issue 3
May-June 2019
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Clinicians' Perspectives on Barriers and Enablers of Optimal Prescribing in Patients with Dementia and Coexisting Conditions
Ariel R. Green, Patricia Lee, Emily Reeve, Jennifer L. Wolff, Chi Chiung Grace Chen, Rachel Kruzan, Cynthia M. Boyd
The Journal of the American Board of Family Medicine May 2019, 32 (3) 383-391; DOI: 10.3122/jabfm.2019.03.180335

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Clinicians' Perspectives on Barriers and Enablers of Optimal Prescribing in Patients with Dementia and Coexisting Conditions
Ariel R. Green, Patricia Lee, Emily Reeve, Jennifer L. Wolff, Chi Chiung Grace Chen, Rachel Kruzan, Cynthia M. Boyd
The Journal of the American Board of Family Medicine May 2019, 32 (3) 383-391; DOI: 10.3122/jabfm.2019.03.180335
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Keywords

  • Adverse Decision Making
  • Drug Reaction
  • Comorbidity
  • Dementia
  • Geriatrics
  • Polypharmacy
  • Potentially Inappropriate Medications
  • Primary Health Care
  • Qualitative Research
  • Risk Assessment

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