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Research ArticleOriginal Research

Clinical Implication of Immunoglobulin G levels in the Management of Patients with Helicobacter pylori Infection

Daniel Wang, Timothy Chiu and Kwok-Wai Chiu
The Journal of the American Board of Family Medicine September 2014, 27 (5) 682-689; DOI: https://doi.org/10.3122/jabfm.2014.05.130181
Daniel Wang
From the College of Natural Sciences, University of Texas at Austin, Austin (DW); the Department of Internal Medicine, Louisiana State University Science Center, Shreveport (TC); and Plano Family Medicine, Plano, TX (K-WC).
BA
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Timothy Chiu
From the College of Natural Sciences, University of Texas at Austin, Austin (DW); the Department of Internal Medicine, Louisiana State University Science Center, Shreveport (TC); and Plano Family Medicine, Plano, TX (K-WC).
MD
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Kwok-Wai Chiu
From the College of Natural Sciences, University of Texas at Austin, Austin (DW); the Department of Internal Medicine, Louisiana State University Science Center, Shreveport (TC); and Plano Family Medicine, Plano, TX (K-WC).
MD, MPH
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  • Article
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  • References
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Article Figures & Data

Figures

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  • Figure 1.
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    Figure 1.

    Comparison of serum immunoglobulin (Ig) G values as units per milliliter in all patients with Helicobacter pylori before and after treatment. Laboratory measurements (units per milliliter) are capped at an 8 U/mL maximum and a 0.4 U/mL minimum.

  • Figure 2.
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    Figure 2.

    Comparison of serum immunoglobulin G (EV) values in all patients with Helicobacter pylori before and after treatment. Laboratory measurements are capped at a 70 EV maximum and a 0.8 EV minimum.

  • Figure 3.
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    Figure 3.

    Comparison of multiple of minimum positive serum immunoglobulin G values in all patients with Helicobacter pylori before and after treatment.

  • Figure 4.
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    Figure 4.

    Timeline of Helicobacter pylori and immunoglobulin G (IgG) value progression in the patient with the longest treatment. UBT, urea breath test.

Tables

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    Table 1. All Serum Immunoglobulin G Values with Corresponding Urea Breath Test Results Taken Within 2 Weeks
    Patient IDMultiple of Minimum Positive ValueUBT Result
    158819.609Detected
    49288Detected
    58688Detected
    60447.5Detected
    69206.7Detected
    43345.3Not detected
    15545.1Detected
    20075Detected
    34024.52Detected
    15684.5Detected
    11764.4Detected
    14464.4Detected
    11063.96Detected
    53233.957Detected
    16313.26Detected
    47943.22Not detected
    50353.2Detected
    47553.1Detected
    16313Detected
    16313Detected
    58252.9Detected
    55232.8Detected
    41742.696Detected
    15542.652Detected
    13552.522Detected
    61342.5Detected
    50322.3Detected
    26252.261Detected
    27642.217Not detected
    36512.2Detected
    37652.2Detected
    69902.2Detected
    20382.174Detected
    54742.13Detected
    22012.1Detected
    24342.087Detected
    10222.043Detected
    53042Not detected
    30041.9Detected
    45091.87Not detected
    27651.8Detected
    37821.8Detected
    51101.8Detected
    12331.761Detected
    18261.7Not detected
    66951.7Detected
    35831.57Not detected
    59011.522Detected
    19521.5Detected
    45981.5Detected
    51111.5Not detected
    15541.478Detected
    50151.4Detected
    64221.4Not detected
    11131.391Not detected
    33121.35Detected
    36051.35Not detected
    38961.348Not detected
    38101.304Not detected
    64091.3Not detected
    13381.26Not detected
    36511.22Detected
    21561.2Not detected
    25981.2Not detected
    29931.2Not detected
    35451.2Not detected
    42971.2Not detected
    52791.2Not detected
    10621.17Not detected
    22711.13Not detected
    30931.13Not detected
    12891.1Not detected
    38791.1Not detected
    40421.1Not detected
    45501.1Detected
    48461.1Not detected
    50551.1Not detected
    30231.087Not detected
    66641.087Not detected
    35471.043Not detected
    43921.043Detected
    19031Not detected
    22841Detected
    39161Not detected
    43821Not detected
    56861Not detected
    70731Detected
    14490.957Not detected
    15540.913Not detected
    70210.913Not detected
    42550.9Not detected
    42550.8Not detected
    12940.783Not detected
    • Data pairs with positive urea breath test (UBT) results (detected) are in bold.

    • View popup
    Table 2. Serum Immunoglobulin G Values with Corresponding Urea Breath Test Results Taken Within 2 Weeks–Before Treatment Only
    Patient IDMultiple of Minimum Positive ValueUBT Result
    158819.609Detected
    49288Detected
    58688Detected
    60447.5Detected
    69206.7Detected
    43345.3Not Detected
    15545.1Detected
    20075Detected
    34024.52Detected
    15684.5Detected
    11764.4Detected
    14464.4Detected
    11063.96Detected
    53233.957Detected
    16313.26Detected
    50353.2Detected
    47553.1Detected
    58252.9Detected
    55232.8Detected
    41742.696Detected
    13552.522Detected
    61342.5Detected
    50322.3Detected
    26252.261Detected
    36512.2Detected
    37652.2Detected
    69902.2Detected
    20382.174Detected
    54742.13Detected
    22012.1Detected
    24342.087Detected
    10222.043Detected
    53042Not Detected
    30041.9Detected
    45091.87Not Detected
    27651.8Detected
    37821.8Detected
    51101.8Detected
    12331.761Detected
    18261.7Not Detected
    66951.7Detected
    35831.57Not Detected
    59011.522Detected
    19521.5Detected
    45981.5Detected
    51111.5Not Detected
    50151.4Detected
    64221.4Not Detected
    11131.391Not Detected
    33121.35Detected
    36051.35Not Detected
    38961.348Not Detected
    38101.304Not Detected
    64091.3Not Detected
    13381.26Not Detected
    21561.2Not Detected
    25981.2Not Detected
    29931.2Not Detected
    35451.2Not Detected
    42971.2Not Detected
    52791.2Not Detected
    10621.17Not Detected
    22711.13Not Detected
    30931.13Not Detected
    12891.1Not Detected
    38791.1Not Detected
    40421.1Not Detected
    45501.1Detected
    48461.1Not Detected
    50551.1Not Detected
    30231.087Not Detected
    66641.087Not Detected
    35471.043Not Detected
    43921.043Detected
    19031Not Detected
    22841Detected
    39161Not Detected
    43821Not Detected
    56861Not Detected
    70731Detected
    14490.957Not Detected
    70210.913Not Detected
    42550.9Not Detected
    12940.783Not Detected
    • Data pairs with positive urea breath test (UBT) results (detected) are in bold.

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The Journal of the American Board of Family     Medicine: 27 (5)
The Journal of the American Board of Family Medicine
Vol. 27, Issue 5
September-October 2014
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Clinical Implication of Immunoglobulin G levels in the Management of Patients with Helicobacter pylori Infection
Daniel Wang, Timothy Chiu, Kwok-Wai Chiu
The Journal of the American Board of Family Medicine Sep 2014, 27 (5) 682-689; DOI: 10.3122/jabfm.2014.05.130181

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Clinical Implication of Immunoglobulin G levels in the Management of Patients with Helicobacter pylori Infection
Daniel Wang, Timothy Chiu, Kwok-Wai Chiu
The Journal of the American Board of Family Medicine Sep 2014, 27 (5) 682-689; DOI: 10.3122/jabfm.2014.05.130181
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