Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM on Bluesky
  • JABFM On Facebook
  • JABFM On Twitter
  • JABFM On YouTube
Research ArticleOriginal Research

Effects of Changing Guidelines on Prescribing Aspirin for Primary Prevention of Cardiovascular Events

Jennifer Hissett, Brittany Folks, Letoynia Coombs, William LeBlanc and Wilson D. Pace
The Journal of the American Board of Family Medicine January 2014, 27 (1) 78-86; DOI: https://doi.org/10.3122/jabfm.2014.01.130030
Jennifer Hissett
From the Louisiana State University Emergency Medicine Residency, New Orleans (JH); the Exempla St. Joseph Hospital Internal Medicine Residency, Denver, CO (BF); and the Department of Family Medicine, University of Colorado School of Medicine, Aurora (LC, WL, WDP).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Brittany Folks
From the Louisiana State University Emergency Medicine Residency, New Orleans (JH); the Exempla St. Joseph Hospital Internal Medicine Residency, Denver, CO (BF); and the Department of Family Medicine, University of Colorado School of Medicine, Aurora (LC, WL, WDP).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Letoynia Coombs
From the Louisiana State University Emergency Medicine Residency, New Orleans (JH); the Exempla St. Joseph Hospital Internal Medicine Residency, Denver, CO (BF); and the Department of Family Medicine, University of Colorado School of Medicine, Aurora (LC, WL, WDP).
MS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
William LeBlanc
From the Louisiana State University Emergency Medicine Residency, New Orleans (JH); the Exempla St. Joseph Hospital Internal Medicine Residency, Denver, CO (BF); and the Department of Family Medicine, University of Colorado School of Medicine, Aurora (LC, WL, WDP).
PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wilson D. Pace
From the Louisiana State University Emergency Medicine Residency, New Orleans (JH); the Exempla St. Joseph Hospital Internal Medicine Residency, Denver, CO (BF); and the Department of Family Medicine, University of Colorado School of Medicine, Aurora (LC, WL, WDP).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. 1.↵
    1. Hayden M,
    2. Pignone M,
    3. Phillips C,
    4. Mulrow C
    . Aspirin for the primary prevention of cardiovascular events: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2002;136:161–72.
    OpenUrlCrossRefPubMedWeb of Science
  2. 2.↵
    Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2009;150:396–404.
    OpenUrlCrossRefPubMedWeb of Science
  3. 3.↵
    1. Hennekens CH,
    2. Dyken ML,
    3. Fuster V
    . Aspirin as a therapeutic agent in cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 1997;96:2751–3.
    OpenUrlFREE Full Text
  4. 4.↵
    1. Peto R,
    2. Gray R,
    3. Collins R,
    4. et al
    . Randomised trial of prophylactic daily aspirin in British male doctors. Br Med J (Clin Res Ed) 1988;296:313–6.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    Final report on the aspirin component of the ongoing Physicians' Health Study. Steering Committee of the Physicians' Health Study Research Group. N Engl J Med 1989;321:129–35.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    1. Hansson L,
    2. Zanchetti A,
    3. Carruthers SG,
    4. et al
    . Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet 1998;351:1755–62.
    OpenUrlCrossRefPubMedWeb of Science
  7. 7.↵
    Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research Framework. Lancet 1998;351:233–41.
    OpenUrlCrossRefPubMedWeb of Science
  8. 8.↵
    1. Ridker PM,
    2. Cook NR,
    3. Lee IM,
    4. et al
    . A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med 2005;352:1293–304.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    1. De Berardis G,
    2. Sacco M,
    3. Strippoli GF,
    4. et al
    . Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials. BMJ 2009;339:b4531.
    OpenUrlAbstract/FREE Full Text
  10. 10.↵
    1. Fleming T,
    2. Nissen SE,
    3. Borer JS,
    4. Armstrong PW
    . Report from the 100th Cardiovascular and Renal Drugs Advisory Committee meeting: US Food and Drug Administration: December 8–9, 2003 Gaithersburg, MD. Circulation 2004;109:e9004–5.
    OpenUrlFREE Full Text
  11. 11.↵
    1. Ethier J,
    2. Bragg-Gresham JL,
    3. Piera L,
    4. et al
    . Aspirin prescription and outcomes in hemodialysis patients: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 2007;50:602–11.
    OpenUrlCrossRefPubMedWeb of Science
  12. 12.↵
    1. Belch J,
    2. MacCuish A,
    3. Campbell I,
    4. et al
    . The Prevention of Progression of Arterial Disease and Diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. BMJ 2008;337:a1840.
    OpenUrlAbstract/FREE Full Text
  13. 13.↵
    1. Ogawa H,
    2. Nakayama M,
    3. Morimoto T,
    4. et al
    . Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial. JAMA 2008;300:2134–41.
    OpenUrlCrossRefPubMedWeb of Science
  14. 14.↵
    1. Baigent C,
    2. Blackwell L,
    3. Collins R,
    4. et al
    . Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 2009;373:1849–60.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.↵
    1. Fowkes FG,
    2. Price JF,
    3. Stewart MC,
    4. et al
    . Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial. JAMA 2010;303:841–8.
    OpenUrlCrossRefPubMedWeb of Science
  16. 16.↵
    1. Goldstein LB,
    2. Adams R,
    3. Alberts MJ,
    4. et al
    . Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline. Stroke 2006;37:1583–633.
    OpenUrlAbstract/FREE Full Text
  17. 17.↵
    1. Colwell JA
    . Aspirin therapy in diabetes. Diabetes Care 1997;20:1767–71.
    OpenUrlFREE Full Text
  18. 18.↵
    1. Colwell JA
    . Aspirin therapy in diabetes. Diabetes Care 2004;27(Suppl 1):S72–3.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Pignone M,
    2. Alberts MJ,
    3. Colwell JA,
    4. et al
    . Aspirin for primary prevention of cardiovascular events in people with diabetes: a position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation. Diabetes Care 2010;33:1395–402.
    OpenUrlFREE Full Text
  20. 20.↵
    1. Hammermeister K
    . A cardiovascular risk reduction learning community in DARTNet. University of Colorado Denver: National Heart, Lung, and Blood Institute, Recovery Act Grant, NIH Challenge Grants and Partnerships Program. 2009.
  21. 21.↵
    1. D'Agostino RB Sr.,
    2. Vasan RS,
    3. Pencina MJ,
    4. et al
    . General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008;117:743–53.
    OpenUrlAbstract/FREE Full Text
  22. 22.↵
    Wolters Kluwer Health. Master Drug Data Base v2.5. Available from: http://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/MDDB. Accessed November 15, 2013.
  23. 23.↵
    1. Seshasai SRK,
    2. Wijesuriya S,
    3. Sivakumaran R,
    4. et al
    . Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials. Arch Intern Med 2012;172:209–16.
    OpenUrlCrossRefPubMedWeb of Science
  24. 24.↵
    1. Folks B,
    2. Leblanc WG,
    3. Staton EW,
    4. Pace WD
    . Reconsidering low-dose aspirin therapy for cardiovascular disease: a study protocol for physician and patient behavioral change. Implement Sci 2011;6:65.
    OpenUrlPubMed
  25. 25.↵
    1. Rothwell PM,
    2. Wilson M,
    3. Price JF,
    4. Belch JF,
    5. Meade TW,
    6. Mehta Z
    . Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet 2012;379:1591–601.
    OpenUrlCrossRefPubMedWeb of Science
  26. 26.↵
    1. Rothwell PM,
    2. Price JF,
    3. Fowkes FG,
    4. et al
    . Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet 2012;379:1602–12.
    OpenUrlCrossRefPubMedWeb of Science
  27. 27.↵
    1. Davis DA,
    2. Taylor-Vaisey A
    . Translating guidelines into practice. A systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines. CMAJ 1997;157:408–16.
    OpenUrlAbstract/FREE Full Text
  28. 28.↵
    1. Shiffman D,
    2. Slawsky K,
    3. Fusfeld L,
    4. Devlin JJ,
    5. Goss TF
    . Cost-effectiveness model of use of genetic testing as an aid in assessing the likely benefit of aspirin therapy for primary prevention of cardiovascular disease. Clin Ther. 2012;34:1387–94.
    OpenUrlPubMed
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family     Medicine: 27 (1)
The Journal of the American Board of Family Medicine
Vol. 27, Issue 1
January-February 2014
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Effects of Changing Guidelines on Prescribing Aspirin for Primary Prevention of Cardiovascular Events
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
1 + 2 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Effects of Changing Guidelines on Prescribing Aspirin for Primary Prevention of Cardiovascular Events
Jennifer Hissett, Brittany Folks, Letoynia Coombs, William LeBlanc, Wilson D. Pace
The Journal of the American Board of Family Medicine Jan 2014, 27 (1) 78-86; DOI: 10.3122/jabfm.2014.01.130030

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Effects of Changing Guidelines on Prescribing Aspirin for Primary Prevention of Cardiovascular Events
Jennifer Hissett, Brittany Folks, Letoynia Coombs, William LeBlanc, Wilson D. Pace
The Journal of the American Board of Family Medicine Jan 2014, 27 (1) 78-86; DOI: 10.3122/jabfm.2014.01.130030
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Notes
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Different Antiplatelet Strategies in Patients With New Ischemic Stroke While Taking Aspirin
  • Family Physicians are Complex Care Physicians and Quality of Care Advancement Experts
  • Google Scholar

More in this TOC Section

  • Integrating Adverse Childhood Experiences and Social Risks Screening in Adult Primary Care
  • A Pilot Comparison of Clinical Data Collection Methods Using Paper, Electronic Health Record Prompt, and a Smartphone Application
  • Associations Between Modifiable Preconception Care Indicators and Pregnancy Outcomes
Show more Original Research

Similar Articles

Keywords

  • Aspirin
  • Cardiovascular Diseases
  • Primary Prevention

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2025 American Board of Family Medicine

Powered by HighWire