Article Figures & Data
Figures
- Figure 1.
Percentage of yes and no answers regarding novelty and usefulness of most commonly found sample drugs. RCT, randomized control trials.
Tables
- Table 1. Characteristics of the Medications Most Commonly Found in Sample Closets and Their Costs
Trade Name Generic Name Date Initially Approved by FDA Sites Containing Sample (n) Indications Most Common Initial Dose AWP* Bystolic Nebivolol 2007 9 Hypertension 5 mg daily $68/30 tabs Crestor Rosuvastatin 2003 9 Hyperlipidemia 10 mg daily $157/30 tabs Januvia Sitagliptin 2006 9 Type 2 diabetes 100 mg daily $244/30 tabs Micardis Telmisartan 1998 9 Hypertension 40 mg daily $124/30 tabs Toviaz Fesoterodine 2008 9 Overactive bladder 4 mg daily $159/30 tabs Avodart Dutasteride 2001 8 Benign prostate hyperplasia 0.5 mg daily $129/30 tabs Cymbalta Duloxetine 2004 8 Depression, anxiety 60 mg daily $183/30 caps Diovan Valsartan 2001 8 Hypertension 80 mg daily $97/30 tabs Lipitor Atorvastatin 1996 8 Hyperlipidemia 20 mg daily $183/30 tabs Lovaza Omega-3-acid ethyl esters 2004 8 Hypertriglyceridemia 4 g daily $190/120 1-g caps Pristiq Desvenlafaxine 2008 8 Depression 50 mg daily $153/30 tabs Seroquel Quetiapine 1997 8 Schizophrenia, bipolar disorder 200 mg BID $749/60 tabs Actos Pioglitazone 1999 7 Type 2 diabetes 30 mg daily Amitiza Lubiprostone 2006 7 Chronic idiopathic constipation 24 μg BID $272/60 caps Celebrex Celecoxib 1998 7 Joint pain 100 mg BID $176/60 caps Enablex Darifenacin 2004 7 Overactive bladder 7.5 mg daily $167/30 tabs Levitra Vardenafil 2003 7 Erectile dysfunction 10 mg $21/tab Maxalt Rizatriptan 1998 7 Migraine headache 5 mg $32/tab Savella Milnacipran 2009 7 Fibromyalgia 50 mg BID $146/60 tabs Spiriva Tiotropium 2004 7 COPD 1 capsule (18 μg) daily $289/30 caps Synthroid Levothyroxine 2002 7 Hypothyroidism 100 μg daily $21/30 tabs Trilipix Fenofibric acid 2008 7 Hyperlipidemia, hypertriglyceridemia 45 mg daily $54/30 caps Vytorin Ezetimibe and simvastatin 2004 7 Hyperlipidemia 10/20 mg daily $148/30 tabs ↵* Cost of a 30-day supply of the most commonly used initial dose of the medication.
AWP, average wholesale price; Cap, capsule; COPD, chronic obstructive pulmonary disease; FDA, US Food and Drug Administration; tab, tablet.
- Table 2. Medications Most Commonly Found in Sample Closets and the Relevant Guideline to Evaluate Usefulness
Trade Name Generic name Relevant Guideline Synthroid Levothyroxine AACE 200214 Maxalt Rizatriptan AAFP/ACP-ASIM 200215 Levitra Vardenafil ACP 201016 Celebrex Celecoxib ACR 201217 Januvia Sitagliptin ADA 201218 Actos Pioglitazone ADA 201218 Cymbalta Duloxetine APA 201019 Pristiq Desvenlafaxine APA 201019 Amitiza Lubiprostone ASCRS 200720 Lovaza Omega-3-acid ethyl esters ATP III 200421 Crestor Rosuvastatin ATP III 200421 Lipitor Atorvastatin ATP III 200421 Trilipix Fenofibric Acid ATP III 200421 Vytorin Ezetimibe and simvastatin ATP III 200421 Avodart Dutasteride AUA22 Savella Milnacipran EULAR 200823 Spiriva Tiotropium GOLD 201024 Bystolic Nebivolol JNC VII25 Micardis Telmisartan JNC VII25 Diovan Valsartan JNC VII25 Toviaz Fesoterodine NICE 200626 Enablex Darifenacin NICE 200626 Seroquel Quetiapine NICE 200627 AACE, American Association of Clinical Endocrinologists; AAFP, American Academy of Family Physicians; ACP-ASIM, American College of Physicians-American Society of Internal Medicine; ADA, American Diabetes Association; ACR, American College of Rheumatism; APA, American Psychiatric Association; ASCRS, American Society of Colon and Rectal Surgeons; ATP, Adult Treatment Panel; AUA, American Urologic Association; EULAR, European League Against Rheumatism; GOLD, Global Initiative for Chronic Obstructive Lung Disease; JNC, Joint National Committee; NICE, National Institute for Clinical Excellence (UK).
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