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Research ArticleOriginal Research

A Comparison of Unsedated Colonoscopy and Flexible Sigmoidoscopy in the Family Medicine Setting: An LA Net Study

Lyndee Knox, Ricardo G. Hahn and Christianne Lane
The Journal of the American Board of Family Medicine September 2007, 20 (5) 444-450; DOI: https://doi.org/10.3122/jabfm.2007.05.060175
Lyndee Knox
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Ricardo G. Hahn
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Christianne Lane
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    Table 1.

    Guidelines for Modified Colon Endoscopy

    Primary indications:
    • Screening for colorectal cancer in asymptomatic patients according to ACS guidelines

    • Rescreening of patients with history of treated colon cancer

      • –Known familial colon cancer history

    • Diagnostic examinations:

      • –Evaluation of positive FOBT

      • –Evaluation of rectal bleeding

      • –Evaluation of change in bowel habits

      • –Follow-up of selected patients previously found to have benign lesions

    Contraindications:
    • Multiple previous abdominal surgical procedures

    • Known active inflammatory bowel disease or diverticulitis

    • Inability to complete or tolerate bowel prep

    • Inability to cooperate because of mental illness, dementia or disability

    Reasons to terminate procedure and refer to consultant endoscopist:
    • Inability to advance endoscope with reasonable effort and within reasonable time

    • Excessive patient discomfort

    • Extensive diverticulosis with inability to identify lumen

    • Discovery of active inflammatory bowel disease or diverticulitis

    • Discovery of multiple lesions that will require extensive polypectomy

    • Discovery of obstructing lesion

    • Discovery of obvious cancer

    • Visual recognition of incompletely removed dysplastic lesion

    Lesions to biopsy using biopsy forceps:
    • All polyps

    • Most abnormal mucosa

    Lesions to NOT biopsy using biopsy forceps:
    • Diverticuli (perforation risk)

    • Flat lesions within diverticuli (perforation risk)

    Lesions to remove with snare:
    • Pedunculated polyps

    Lesions to NOT remove with snare:
    • Broad-based polyps (perforation risk)

    • Lesions within diverticuli (perforation risk)

    • View popup
    Table 2.

    Sample Characteristics for Modified Colon Endoscopy and Flexible Sigmoidoscopy Groups

    CharacteristicMCE† (n = 48)FS‡ (n = 35)
    Age*
        <40 years2 (4.2)6 (17.1)
        40–496 (12.5)8 (22.9)
        50–5916 (33.3)12 (34.3)
        60–6917 (35.4)6 (17.1)
        70+6 (12.5)2 (5.7)
    Female16 (33.3)14 (40.0)
    Ethnicity
        Caucasian22 (45.8)24 (68.6)
        Black/African American4 (8.3)1 (2.9)
        Latino14 (29.2)5 (14.3)
        Asian5 (10.4)4 (11.4)
        Other2 (4.2)1 (2.9)
    • * P < .05.

    • † Mean, 59.6, SD, 12.5; range, 31.2–86.2.

    • ‡ Mean, 51.3, SD, 13.4; range, 25.7–80.0.

    • All data shown as N (%). MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.

    • View popup
    Table 3.

    Completion Rate, Site Visualized, Depth Reached, Complications

    MCE (n = 48)FS (n = 35)
    Procedure completed40 (83.3)24 (75.0)
    Reasons for noncompletion
        Bleeding0 (0.0)0 (0.0)
        Discomfort4 (8.3)4 (11.4)
        Excessive looping0 (0.0)0 (0.0)
        Poor preparation3 (6.3)0 (0.0)
        Obstructing mass2 (4.2)0 (0.0)
        Not specified0 (0.0)7 (63.6)
    Reached maximum depth* (160 cm for ME/60 cm for FS)9 (18.8)14 (40.0)
    Anatomical site visualized*
        Sigmoid colon0 (0.0)1 (2.9)
        Descending colon0 (0.0)11 (31.4)
        Splenic flexure2 (4.2)12 (34.3)
        Transverse colon6 (12.5)9 (25.7)
        Hepatic flexure1 (2.1)0 (0.0)
        Ascending colon35 (72.9)0 (0.0)
        Cecum3 (6.3)0 (0.0)
    Maximum depth (cm) for procedure*†
        0–200 (0.0)1 (2.9)
        21–400 (0.0)6 (17.1)
        41–603 (6.3)28 (80.0)
        61–801 (2.1)0 (0.0)
        81–1003 (6.3)0 (0.0)
        101–1207 (14.6)0 (0.0)
        121–14015 (31.3)0 (0.0)
        141–16019 (39.6)0 (0.0)
    Complications reported (bleeding, infection, perforation, and other)0 (0.0)0 (0.0)
    • * P < .05

    • † For MCE: mean, 130.1; SE, 30.1. For FS: mean, 50.6; SD, 10.0.

    • All data presented as N (%). MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.

    • View popup
    Table 4.

    Descriptive Data About Clinical Findings for Modified Colon Endoscopy and Flexible Sigmoidoscopy

    MCE (n = 48)FS (n = 35)
    Normal Colon16 (33.3)20 (57.1)
    Diverticula16 (33.3)6 (17.1)
    Hemorrhoids4 (8.3)4 (11.4)
    Inflammatory Bowel Disease3 (6.3)0 (0.0)
    Mass lesions1 (2.1)0 (0.0)
    Polyps6 (12.5)4 (11.4)
    Adenocarcinoma4 (8.3)0 (0.0)
    Hyperperistalisis2 (4.2)4 (11.4)
    Other7 (14.6)0 (0.0)
    • MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.

    • View popup
    Table 5.

    Variations in Outcomes by Clinician

    MCE*FS†
    χ2(3)Pχ2(5)P
    Procedure completed2.980.401.860.87
    Noncompletion
        Discomfort3.150.373.750.59
        Poor Preparation2.420.49——
    Findings
        Normal Colon3.400.336.980.22
        Diverticula0.650.875.240.39
        Hemorrhoids2.360.507.720.17
        Infl. Bowel Disease2.860.41——
        Mass Lesions0.540.91——
        Polyps5.330.150.2330.80
        Hyperperistalisis1.270.74——
        Other4.970.1710.780.06
    • * Number of clinicians = 4.

    • † Number of clinicians = 6.

    • MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.

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The Journal of the American Board of Family Medicine: 20 (5)
The Journal of the American Board of Family Medicine
Vol. 20, Issue 5
September-October 2007
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A Comparison of Unsedated Colonoscopy and Flexible Sigmoidoscopy in the Family Medicine Setting: An LA Net Study
Lyndee Knox, Ricardo G. Hahn, Christianne Lane
The Journal of the American Board of Family Medicine Sep 2007, 20 (5) 444-450; DOI: 10.3122/jabfm.2007.05.060175

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A Comparison of Unsedated Colonoscopy and Flexible Sigmoidoscopy in the Family Medicine Setting: An LA Net Study
Lyndee Knox, Ricardo G. Hahn, Christianne Lane
The Journal of the American Board of Family Medicine Sep 2007, 20 (5) 444-450; DOI: 10.3122/jabfm.2007.05.060175
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