Article Figures & Data
Tables
Primary indications: Screening for colorectal cancer in asymptomatic patients according to ACS guidelines
Rescreening of patients with history of treated colon cancer
–Known familial colon cancer history
Diagnostic examinations:
–Evaluation of positive FOBT
–Evaluation of rectal bleeding
–Evaluation of change in bowel habits
–Follow-up of selected patients previously found to have benign lesions
Contraindications: Multiple previous abdominal surgical procedures
Known active inflammatory bowel disease or diverticulitis
Inability to complete or tolerate bowel prep
Inability to cooperate because of mental illness, dementia or disability
Reasons to terminate procedure and refer to consultant endoscopist: Inability to advance endoscope with reasonable effort and within reasonable time
Excessive patient discomfort
Extensive diverticulosis with inability to identify lumen
Discovery of active inflammatory bowel disease or diverticulitis
Discovery of multiple lesions that will require extensive polypectomy
Discovery of obstructing lesion
Discovery of obvious cancer
Visual recognition of incompletely removed dysplastic lesion
Lesions to biopsy using biopsy forceps: All polyps
Most abnormal mucosa
Lesions to NOT biopsy using biopsy forceps: Diverticuli (perforation risk)
Flat lesions within diverticuli (perforation risk)
Lesions to remove with snare: Pedunculated polyps
Lesions to NOT remove with snare: Broad-based polyps (perforation risk)
Lesions within diverticuli (perforation risk)
- Table 2.
Sample Characteristics for Modified Colon Endoscopy and Flexible Sigmoidoscopy Groups
Characteristic MCE† (n = 48) FS‡ (n = 35) Age* <40 years 2 (4.2) 6 (17.1) 40–49 6 (12.5) 8 (22.9) 50–59 16 (33.3) 12 (34.3) 60–69 17 (35.4) 6 (17.1) 70+ 6 (12.5) 2 (5.7) Female 16 (33.3) 14 (40.0) Ethnicity Caucasian 22 (45.8) 24 (68.6) Black/African American 4 (8.3) 1 (2.9) Latino 14 (29.2) 5 (14.3) Asian 5 (10.4) 4 (11.4) Other 2 (4.2) 1 (2.9) * P < .05.
† Mean, 59.6, SD, 12.5; range, 31.2–86.2.
‡ Mean, 51.3, SD, 13.4; range, 25.7–80.0.
All data shown as N (%). MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.
MCE (n = 48) FS (n = 35) Procedure completed 40 (83.3) 24 (75.0) Reasons for noncompletion Bleeding 0 (0.0) 0 (0.0) Discomfort 4 (8.3) 4 (11.4) Excessive looping 0 (0.0) 0 (0.0) Poor preparation 3 (6.3) 0 (0.0) Obstructing mass 2 (4.2) 0 (0.0) Not specified 0 (0.0) 7 (63.6) Reached maximum depth* (160 cm for ME/60 cm for FS) 9 (18.8) 14 (40.0) Anatomical site visualized* Sigmoid colon 0 (0.0) 1 (2.9) Descending colon 0 (0.0) 11 (31.4) Splenic flexure 2 (4.2) 12 (34.3) Transverse colon 6 (12.5) 9 (25.7) Hepatic flexure 1 (2.1) 0 (0.0) Ascending colon 35 (72.9) 0 (0.0) Cecum 3 (6.3) 0 (0.0) Maximum depth (cm) for procedure*† 0–20 0 (0.0) 1 (2.9) 21–40 0 (0.0) 6 (17.1) 41–60 3 (6.3) 28 (80.0) 61–80 1 (2.1) 0 (0.0) 81–100 3 (6.3) 0 (0.0) 101–120 7 (14.6) 0 (0.0) 121–140 15 (31.3) 0 (0.0) 141–160 19 (39.6) 0 (0.0) Complications reported (bleeding, infection, perforation, and other) 0 (0.0) 0 (0.0) * P < .05
† For MCE: mean, 130.1; SE, 30.1. For FS: mean, 50.6; SD, 10.0.
All data presented as N (%). MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.
- Table 4.
Descriptive Data About Clinical Findings for Modified Colon Endoscopy and Flexible Sigmoidoscopy
MCE (n = 48) FS (n = 35) Normal Colon 16 (33.3) 20 (57.1) Diverticula 16 (33.3) 6 (17.1) Hemorrhoids 4 (8.3) 4 (11.4) Inflammatory Bowel Disease 3 (6.3) 0 (0.0) Mass lesions 1 (2.1) 0 (0.0) Polyps 6 (12.5) 4 (11.4) Adenocarcinoma 4 (8.3) 0 (0.0) Hyperperistalisis 2 (4.2) 4 (11.4) Other 7 (14.6) 0 (0.0) MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.
MCE* FS† χ2(3) P χ2(5) P Procedure completed 2.98 0.40 1.86 0.87 Noncompletion Discomfort 3.15 0.37 3.75 0.59 Poor Preparation 2.42 0.49 — — Findings Normal Colon 3.40 0.33 6.98 0.22 Diverticula 0.65 0.87 5.24 0.39 Hemorrhoids 2.36 0.50 7.72 0.17 Infl. Bowel Disease 2.86 0.41 — — Mass Lesions 0.54 0.91 — — Polyps 5.33 0.15 0.233 0.80 Hyperperistalisis 1.27 0.74 — — Other 4.97 0.17 10.78 0.06 * Number of clinicians = 4.
† Number of clinicians = 6.
MCE, modified colon endoscopy; FS, flexible sigmoidoscopy.