Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM On Twitter
  • JABFM On YouTube
  • JABFM On Facebook
Research ArticleOriginal Article

Buspirone Effect On Tobacco Withdrawal Symptoms: A Pilot Study

Mark D. Robinson, Wiley A. Smith, Eric A. Cederstrom and Donald E. Sutherland
The Journal of the American Board of Family Practice March 1991, 4 (2) 89-94; DOI: https://doi.org/10.3122/jabfm.4.2.89
Mark D. Robinson
From the Department of Family Practice, Carolinas Medical Center, Charlotte, NC, and the Department of Family Practice, Dwight D. Eisenhower Army Medical Center, Fort Gordon, GA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wiley A. Smith
From the Department of Family Practice, Carolinas Medical Center, Charlotte, NC, and the Department of Family Practice, Dwight D. Eisenhower Army Medical Center, Fort Gordon, GA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eric A. Cederstrom
From the Department of Family Practice, Carolinas Medical Center, Charlotte, NC, and the Department of Family Practice, Dwight D. Eisenhower Army Medical Center, Fort Gordon, GA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Donald E. Sutherland
From the Department of Family Practice, Carolinas Medical Center, Charlotte, NC, and the Department of Family Practice, Dwight D. Eisenhower Army Medical Center, Fort Gordon, GA.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • References
  • Info & Metrics
  • PDF
Loading

Abstract

Tobacco withdrawal symptoms hamper smoking cessation. This was a pilot study of buspirone, a new azapirone anxiolytic, for tobacco withdrawal. Thirteen smokers entered an open clinical trial. Smokers were titrated to 30 mg/day of oral buspirone for 2 weeks prior to cessation. Tobacco withdrawal and Spielberger state-anxiety scales were used at baseline, on the quit date, and then at 24 hours, 48 hours, 1 week, and 2 weeks after abrupt cessation. At the final visit, smokers compared their withdrawal experience with previous cessation attempts.

Two patients (15 percent) could not tolerate the medication and did not attempt smoking cessation. Of the remaining 11 smokers, 3 (27 percent) rated withdrawal relief “very definite,” 6 (55 percent) “moderate,” and 2 (18 percent) “slight.” More than two-thirds of the smokers believed that their difficulty concentrating, craving, restlessness, and anxiety were improved compared with earlier tobacco withdrawal attempts. Five patients (46 percent) reported decreased smoking urges during the 2-week medication titration period. Tobacco withdrawal symptoms and state-anxiety scores changed significantly during the study (P < 0.05).

These results are encouraging, but they should be interpreted with caution because of the small sample size and lack of placebo control. Buspirone effect on tobacco withdrawal symptoms should be studied in a randomized, controlled clinical trial.

PreviousNext
Back to top

In this issue

The Journal of the American Board of Family     Practice: 4 (2)
The Journal of the American Board of Family Practice
Vol. 4, Issue 2
1 Mar 1991
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Buspirone Effect On Tobacco Withdrawal Symptoms: A Pilot Study
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
2 + 0 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Buspirone Effect On Tobacco Withdrawal Symptoms: A Pilot Study
Mark D. Robinson, Wiley A. Smith, Eric A. Cederstrom, Donald E. Sutherland
The Journal of the American Board of Family Practice Mar 1991, 4 (2) 89-94; DOI: 10.3122/jabfm.4.2.89

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Buspirone Effect On Tobacco Withdrawal Symptoms: A Pilot Study
Mark D. Robinson, Wiley A. Smith, Eric A. Cederstrom, Donald E. Sutherland
The Journal of the American Board of Family Practice Mar 1991, 4 (2) 89-94; DOI: 10.3122/jabfm.4.2.89
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Screening for Dementia: Family Caregiver Questionnaires Reliably Predict Dementia
  • Help-Seeking for Insomnia among Adult Patients in Primary Care
  • How Much Time Do Patients with Diabetes Spend on Self-Care?
Show more Original Articles

Similar Articles

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2023 American Board of Family Medicine

Powered by HighWire