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Research ArticleArticle

Food Insecurity Is Associated with Vitamin B12 Deficiency: The All of Us Database

Daniel J. Parente
The Journal of the American Board of Family Medicine November 2024, 37 (Supplement2) S156-S163; DOI: https://doi.org/10.3122/jabfm.2023.230454R1
Daniel J. Parente
From the Family Medicine and Community Health, University of Kansas Medical Center, Kansas City, KS.
MD, PhD
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References

  1. 1.↵
    1. Nielsen MJ,
    2. Rasmussen MR,
    3. Andersen CBF,
    4. Nexø E,
    5. Moestrup SK
    . Vitamin B12 transport from food to the body’s cells–a sophisticated, multistep pathway. Nat Rev Gastroenterol Hepatol 2012;9:345–54.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Stabler SP
    . Clinical practice. Vitamin B12 deficiency. N Engl J Med 2013;368:149–60.
    OpenUrlCrossRefPubMedWeb of Science
  3. 3.↵
    1. Green R,
    2. Allen LH,
    3. Bjørke-Monsen AL,
    4. et al
    . Vitamin B12 deficiency. Nat Rev Dis Primers 2017;3:17040.
    OpenUrlPubMed
  4. 4.↵
    1. Lindenbaum J,
    2. Rosenberg IH,
    3. Wilson PW,
    4. Stabler SP,
    5. Allen RH
    . Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 1994;60:2–11.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    1. Wright JD,
    2. Bialostosky K,
    3. Gunter EW,
    4. et al
    . Blood folate and vitamin B12: United States, 1988-94. Vital Health Stat 11 1998;243;11:1–78.
    OpenUrl
  6. 6.↵
    1. Karakaş NM
    . The prevalence of low serum levels of vitamin D, vitamin B12, folate and ferritin in adolescents: Single center experience. Sci Prog 2021;104:368504211007667.
    OpenUrlPubMed
  7. 7.↵
    1. Yousef Khan F,
    2. Yousif AB,
    3. Suliman A,
    4. et al
    . Association of vitamin B12 deficiency with metformin use in patients with type 2 diabetes treated in the largest tertiary care hospital in Qatar. Qatar Med J 2021;2021:39.
    OpenUrlPubMed
  8. 8.↵
    1. Nandyala S,
    2. Mohamed A,
    3. Bhargava A,
    4. Chaurasia S,
    5. Senthil S,
    6. Vaddavalli PK
    . Vitamin B12 deficiency in a large cohort of healthcare professionals across the network of an eyecare organization in India. Indian J Ophthalmol 2022;70:1718–21.
    OpenUrlPubMed
  9. 9.↵
    1. Berardi G,
    2. Vitiello A,
    3. Abu-Abeid A,
    4. et al
    . Micronutrients deficiencies in candidates of bariatric surgery: results from a single institution over a 1-year period. Obes Surg 2023;33:212–8.
    OpenUrlPubMed
  10. 10.↵
    1. Saxena R,
    2. Liu X,
    3. Navas-Acien A,
    4. et al
    . Nutrition, one-carbon metabolism and arsenic methylation in Bangladeshi adolescents. Environ Res 2021;195:110750.
    OpenUrl
  11. 11.↵
    1. Alvarez M,
    2. Sierra OR,
    3. Saavedra G,
    4. Moreno S
    . Vitamin B12 deficiency and diabetic neuropathy in patients taking metformin: a cross-sectional study. Endocr Connect 2019;8:1324–9.
    OpenUrlPubMed
  12. 12.↵
    1. Ramírez-Vélez R,
    2. Correa-Bautista JE,
    3. Martínez-Torres J,
    4. Meneses-Echávez JF,
    5. Lobelo F
    . Vitamin B12 concentration and its association with sociodemographic factors in Colombian children: Findings from the 2010 National Nutrition Survey. Nutrition 2016;32:255–9.
    OpenUrlPubMed
  13. 13.↵
    1. Herrán OF,
    2. Ward JB,
    3. Villamor E
    . Vitamin B12 serostatus in Colombian children and adult women: results from a nationally representative survey. Public Health Nutr 2015;18:836–43.
    OpenUrlCrossRefPubMed
  14. 14.↵
    1. Benson J,
    2. Phillips C,
    3. Kay M,
    4. et al
    . Low vitamin B12 levels among newly-arrived refugees from Bhutan, Iran and Afghanistan: a multicentre Australian study. PloS One 2013;8:e57998.
    OpenUrlCrossRefPubMed
  15. 15.↵
    1. Mineva EM,
    2. Sternberg MR,
    3. Bailey RL,
    4. Storandt RJ,
    5. Pfeiffer CM
    . Fewer US adults had low or transitional vitamin B12 status based on the novel combined indicator of vitamin B12 status compared with individual, conventional markers, NHANES 1999–2004. Am J Clin Nutr 2021;114:1070–9.
    OpenUrlPubMed
  16. 16.↵
    1. Alhaji JH
    . Vitamin B12 deficiency in patients with diabetes on metformin: Arab countries. Nutrients 2022;14.
  17. 17.↵
    1. Niafar M,
    2. Hai F,
    3. Porhomayon J,
    4. Nader ND
    . The role of metformin on vitamin B12 deficiency: a meta-analysis review. Intern Emerg Med 2015;10:93–102.
    OpenUrlPubMed
  18. 18.↵
    1. Liu Q,
    2. Li S,
    3. Quan H,
    4. Li J
    . Vitamin B12 status in metformin treated patients: systematic review. Pietropaolo M, ed. PLoS ONE 2014;9:e100379.
    OpenUrlCrossRefPubMed
  19. 19.↵
    American Diabetes Association. 9. pharmacologic approaches to glycemic treatment: standards of medical care in diabetes—2019. Diabetes Care 2018;42:S90–S102.
    OpenUrlCrossRef
  20. 20.↵
    1. Avery A
    . Food insecurity and malnutrition. Komp Nutr Diet 2021;1:41–3.
    OpenUrl
  21. 21.↵
    1. Denny JC,
    2. Rutter JL,
    3. Goldstein DB
    , All of Us Research Program Investigators, et al. The “All of Us” research program. N Engl J Med. 2019;381:668–76.
    OpenUrlCrossRefPubMed
  22. 22.↵
    1. Mapes BM,
    2. Foster CS,
    3. Kusnoor SV
    , All of Us Research Program, et al. Diversity and inclusion for the All of Us research program: a scoping review. PloS One 2020;15:e0234962.
    OpenUrlCrossRefPubMed
  23. 23.↵
    1. Chandler PD,
    2. Clark CR,
    3. Zhou G
    , All of Us Research Program Investigators, et al. Hypertension prevalence in the All of Us research program among groups traditionally underrepresented in medical research. Sci Rep . 2021;11:12849.
    OpenUrlPubMed
  24. 24.↵
    1. Devineni D,
    2. Akbarpour M,
    3. Gong Y,
    4. Wong ND
    . Inadequate use of newer treatments and glycemic control by cardiovascular risk and sociodemographic groups in US Adults with diabetes in the NIH Precision Medicine Initiative All of Us Research Program. Cardiovasc Drugs Ther 2022;38:347–57. Published online November 15.
    OpenUrlPubMed
  25. 25.↵
    1. Nagar SD,
    2. Pemu P,
    3. Qian J
    , SEEC Consortium, et al. Investigation of hypertension and type 2 diabetes as risk factors for dementia in the All of Us cohort. Sci Rep . 2022;12:19797.
    OpenUrlPubMed
  26. 26.↵
    1. Perry AS,
    2. Annis JS,
    3. Master H,
    4. et al
    . Association of longitudinal activity measures and diabetes risk: an analysis from the National Institutes of Health All of Us research program. J Clin Endocrinol Metab 2023;108:1101–9.
    OpenUrlCrossRefPubMed
  27. 27.↵
    1. Fischbach FT,
    2. Fischbach MA
    . Fischbach’s a manual of laboratory and diagnostic tests. 10th edition. LWW; 2017.
  28. 28.↵
    1. Aparicio-Ugarriza R,
    2. Palacios G,
    3. Alder M,
    4. González-Gross M
    . A review of the cut-off points for the diagnosis of vitamin B12 deficiency in the general population. Clin Chem Lab Med 2015;53:1149–59.
    OpenUrlPubMed
  29. 29.↵
    1. Koehler KM,
    2. Romero LJ,
    3. Stauber PM,
    4. et al
    . Vitamin supplementation and other variables affecting serum homocysteine and methylmalonic acid concentrations in elderly men and women. J Am Coll Nutr 1996;15:364–76.
    OpenUrlPubMedWeb of Science
  30. 30.↵
    1. Rajan S,
    2. Wallace JI,
    3. Beresford SAA,
    4. Brodkin KI,
    5. Allen RA,
    6. Stabler SP
    . Screening for cobalamin deficiency in geriatric outpatients: prevalence and influence of synthetic cobalamin intake. J Am Geriatr Soc 2002;50:624–30.
    OpenUrlCrossRefPubMedWeb of Science
  31. 31.↵
    1. Pennypacker LC,
    2. Allen RH,
    3. Kelly JP,
    4. et al
    . High prevalence of cobalamin deficiency in elderly outpatients.J American Geriatrics Society 1992;40:1197–204.
    OpenUrl
  32. 32.↵
    United States Department of Agriculture. USDA ERS - Food security and nutrition assistance. USDA.gov. Accessed February 2, 2024. Available at: https://www.ers.usda.gov/data-products/ag-and-food-statistics-charting-the-essentials/food-security-and-nutrition-assistance/.
  33. 33.↵
    Health Leads. The Health Leads screening toolkit. Health Leads. Published November 30, 2022. Accessed February 2, 2024. Available at: https://healthleadsusa.org/news-resources/the-health-leads-screening-toolkit/.
  34. 34.↵
    1. Margalit I,
    2. Cohen E,
    3. Goldberg E,
    4. Krause I
    . Vitamin B12 deficiency and the role of gender: a cross-sectional study of a large cohort. Ann Nutr Metab 2018;72:265–71.
    OpenUrlCrossRefPubMed
  35. 35.↵
    1. Chakraborty S,
    2. Chopra M,
    3. Mani K,
    4. et al
    . Prevalence of vitamin B12 deficiency in healthy Indian school-going adolescents from rural and urban localities and its relationship with various anthropometric indices: a cross-sectional study. J Hum Nutr Diet Off J et 2018;31:513–22.
    OpenUrl
  36. 36.↵
    1. Rustgi SD,
    2. Bijlani P,
    3. Shah SC
    . Autoimmune gastritis, with or without pernicious anemia: epidemiology, risk factors, and clinical management. Therap Adv Gastroenterol 2021;14:17562848211038771.
    OpenUrlCrossRefPubMed
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The Journal of the American Board of Family     Medicine: 37 (Supplement2)
The Journal of the American Board of Family Medicine
Vol. 37, Issue Supplement2
November 2024
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Food Insecurity Is Associated with Vitamin B12 Deficiency: The All of Us Database
Daniel J. Parente
The Journal of the American Board of Family Medicine Nov 2024, 37 (Supplement2) S156-S163; DOI: 10.3122/jabfm.2023.230454R1

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Food Insecurity Is Associated with Vitamin B12 Deficiency: The All of Us Database
Daniel J. Parente
The Journal of the American Board of Family Medicine Nov 2024, 37 (Supplement2) S156-S163; DOI: 10.3122/jabfm.2023.230454R1
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Keywords

  • ADFM/NAPCRG Research Summitt 2023
  • Food Insecurity
  • Logistic Regression
  • Multicenter Studies
  • Precision Medicine
  • Retrospective Studies
  • Social Determinants of Health
  • Vitamin B12
  • Vitamin B12 Deficiency

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