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Research ArticleOriginal Research

What Patients Call Their Inhalers Is Associated with “Asthma Attacks”

Victoria E. Forth, Juan Carlos Cardet, Ku-Lang Chang, Brianna Ericson, Laura P. Hurley, Nancy E. Maher, Elizabeth W. Staton, Bonnie Telón Sosa, Elliot Israel and on behalf of the PREPARE investigators
The Journal of the American Board of Family Medicine August 2023, 36 (4) 650-661; DOI: https://doi.org/10.3122/jabfm.2022.220270R2
Victoria E. Forth
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MA, MMS, PA-C
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Juan Carlos Cardet
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MD, MPH
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Ku-Lang Chang
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MD
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Brianna Ericson
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MPH
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Laura P. Hurley
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MD, MPH
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Nancy E. Maher
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MPH
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Elizabeth W. Staton
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MSTC
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Bonnie Telón Sosa
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MPH
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Elliot Israel
From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
MD
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From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
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Article Information

vol. 36 no. 4 650-661
DOI 
https://doi.org/10.3122/jabfm.2022.220270R2
PubMed 
37468217

Published By 
The Journal of the American Board of Family Medicine
Print ISSN 
1557-2625
Online ISSN 
1558-7118
History 
  • Received for publication August 5, 2022
  • Revision received November 8, 2023
  • Accepted for publication March 6, 2023
  • Published online August 10, 2023.

Article Versions

  • previous version (July 19, 2023 - 08:54).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© Copyright by the American Board of Family Medicine.

Author Information

  1. Victoria E. Forth, MA, MMS, PA-C*,
  2. Juan Carlos Cardet, MD, MPH*,
  3. Ku-Lang Chang, MD,
  4. Brianna Ericson, MPH,
  5. Laura P. Hurley, MD, MPH,
  6. Nancy E. Maher, MPH,
  7. Elizabeth W. Staton, MSTC,
  8. Bonnie Telón Sosa, MPH,
  9. Elliot Israel, MD,
  10. on behalf of the PREPARE investigators**
  1. From the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA (VEF, BE, NEM, EI, PAH, JK, JRL, JC, JDS); Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL (JCC); Denver Health and Hospital Authority, Denver, CO (LPH); Lucas Research, Morehead City, NC (KLC); American Academy of Family Physicians National Research Network, Leawood, KS (EWS, JKC, BKM, WDP, JBS); University of Colorado Department of Family Medicine, Aurora, CO (EWS, JKC); Department of Internal Medicine, Allergy/Immunology Section, University of Puerto Rico, San Juan, PR (BTS); Division of Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA (EI); Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO (ALF); DARTNet Institute, Aurora, CO (WDP); Division of Immunology, Boston Children’s Hospital, Boston, MA (WP); University of Miami Health System, Miami, FL (MF); Division of Allergy and Immunology, Department of Medicine, NorthShore University Health System, Glenview, IL (GM); Morehouse School of Medicine, Atlanta, GA (FO).
  1. Corresponding author: Elliot Israel, MD, Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115 (E-mail: eisrael{at}bwh.harvard.edu).
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The Journal of the American Board of Family     Medicine: 36 (4)
The Journal of the American Board of Family Medicine
Vol. 36, Issue 4
July-August 2023
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What Patients Call Their Inhalers Is Associated with “Asthma Attacks”
Victoria E. Forth, Juan Carlos Cardet, Ku-Lang Chang, Brianna Ericson, Laura P. Hurley, Nancy E. Maher, Elizabeth W. Staton, Bonnie Telón Sosa, Elliot Israel, on behalf of the PREPARE investigators
The Journal of the American Board of Family Medicine Aug 2023, 36 (4) 650-661; DOI: 10.3122/jabfm.2022.220270R2

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What Patients Call Their Inhalers Is Associated with “Asthma Attacks”
Victoria E. Forth, Juan Carlos Cardet, Ku-Lang Chang, Brianna Ericson, Laura P. Hurley, Nancy E. Maher, Elizabeth W. Staton, Bonnie Telón Sosa, Elliot Israel, on behalf of the PREPARE investigators
The Journal of the American Board of Family Medicine Aug 2023, 36 (4) 650-661; DOI: 10.3122/jabfm.2022.220270R2
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  • Asthma
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