Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM on Bluesky
  • JABFM On Facebook
  • JABFM On Twitter
  • JABFM On YouTube
Research ArticleOriginal Research

Mental Health and Benzodiazepine Use Among Patients on Chronic Opioid Therapy

Abigail Y. Smith, Julienne K. Kirk, Paul F. Smith and Brian J. Wells
The Journal of the American Board of Family Medicine January 2021, 34 (1) 99-104; DOI: https://doi.org/10.3122/jabfm.2021.01.200320
Abigail Y. Smith
From the Department of Family and Community Medicine, Wake Forest School of Medicine, Winston-Salem, NC (AYS, JKK, BJW); Department of Information Technology Services, Wake Forest School of Medicine, Winston-Salem, NC (PFS); Division of Public Health Sciences, Department of Biostatistical Sciences, Center for Biomedical Informatics, Winston-Salem, NC (BJW).
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Julienne K. Kirk
From the Department of Family and Community Medicine, Wake Forest School of Medicine, Winston-Salem, NC (AYS, JKK, BJW); Department of Information Technology Services, Wake Forest School of Medicine, Winston-Salem, NC (PFS); Division of Public Health Sciences, Department of Biostatistical Sciences, Center for Biomedical Informatics, Winston-Salem, NC (BJW).
PharmD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paul F. Smith
From the Department of Family and Community Medicine, Wake Forest School of Medicine, Winston-Salem, NC (AYS, JKK, BJW); Department of Information Technology Services, Wake Forest School of Medicine, Winston-Salem, NC (PFS); Division of Public Health Sciences, Department of Biostatistical Sciences, Center for Biomedical Informatics, Winston-Salem, NC (BJW).
BS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Brian J. Wells
From the Department of Family and Community Medicine, Wake Forest School of Medicine, Winston-Salem, NC (AYS, JKK, BJW); Department of Information Technology Services, Wake Forest School of Medicine, Winston-Salem, NC (PFS); Division of Public Health Sciences, Department of Biostatistical Sciences, Center for Biomedical Informatics, Winston-Salem, NC (BJW).
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

Article Figures & Data

Tables

    • View popup
    Table 1.

    Demographic Characteristics, Mental Health Diagnoses, Opioid Daily Dose, and Benzodiazepine Prescriptions Among Patients on Chronic Opioid Therapy in 2018 and 2019

    20182019P
    N387231
    Age, mean (SD)60.60 (12.59)59.75 (11.57).404
    Male gender, n (%)140 (36.2)72 (31.2).238
    Race, n (%)    .053
     Black or African American154 (39.8)73 (31.6)
     White or Caucasian229 (59.2)152 (65.8)
     Other4 (1.0)6 (2.6)
    Ethnicity, n (%)    .245
     Hispanic or Latino2 (0.5)4 (1.7)
     Not Hispanic or Latino384 (99.2)227 (98.3)
     Patient refused1 (0.3)0 (0.0)
    Any psychiatric diagnosis, n (%)193 (49.9)213 (92.2)< .001
    Depression, n (%)101 (26.1)154 (66.7)< .001
    Anxiety, n (%)109 (28.2)140 (60.6)< .001
    Bipolar, n (%)21 (5.4)20 (8.7).163
    Adjustment, n (%)43 (11.1)70 (30.3)< .001
    PTSD, n (%)6 (1.6)12 (5.2).018
    Other, n (%)24 (6.2)39 (16.9)< .001
    MME daily dose    .03
     ≥ 90 MME, n (%)31 (8.0)30 (13.0)
     50 to 89.9 MME, n (%)40 (10.3)33 (14.3)
     < 50 MME, n (%)316 (81.7)168 (72.7)
    Benzodiazepine Rx n (%)121 (31.3)77 (33.3).657
    • MME, morphine milligram equivalent; SD, standard deviation; PTSD, post-traumatic stress disorder.

    • View popup
    Table 2.

    Transition of Patients between Benzodiazepine Prescription Categories from 2018 to 2019, Classified by MME Daily Dose Category

    2019 Category
    2018 Category< 50 MME without Benzodiazepine≥ 50 MME without Benzodiazepine< 50 MME with Benzodiazepine≥ 50 MME with BenzodiazepineNo VisitsNot on Chronic Opioids
    < 50 MME without benzodiazepine (n = 226)40131972145
    ≥ 50 MME without Benzodiazepine (n = 40)14534014
    < 50 MME with Benzodiazepine (n = 90)31584042
    ≥ 50 MME with Benzodiazepine (n = 31)1355314
    Total (n = 387)982835183205
    • MME, morphine milligram equivalent.

    • View popup
    Table 3.

    Transition of Patients between Mental Health Diagnosis Categories from 2018 to 2019, Classified by MME Daily Dose Category

    2019 Category
    2018 Category< 50 MME without Psych Dx≥ 50 MME without Psych Dx< 50 MME with Psych Dx ≥ 50 MME with Psych DxNo VisitsNot on Chronic Opioids
    < 50 MME without psych diagnosis (n = 165)1432632117
    ≥ 50 MME without psych diagnosis (n = 29)4154015
    < 50 MME with psych dx (n = 151) 1564317070
    ≥ 50 MME with psych diagnosis (n = 42)4722513
    Total (n = 387)371796293205
    • MME, morphine milligram equivalent.

    • View popup
    Table 4.

    Odds of Remaining in the Same or Higher MME per Day Dose Category Based on Patient Characteristics

    Odds Ratio95% CI
    White versus nonwhite1.621.00 to 2.61
    Psychiatric diagnosis versus none2.731.71 to 4.37
    Benzodiazepine prescription versus none1.170.70 to 1.95
    Gender male versus female0.670.42 to 1.09
    50 to 89.9 MME per day versus < 50 MME per day2.181.05 to 4.50
    ≥ 90 MME per day versus < 50 MME per day2.751.52 to 6.59
    • MME, morphine milligram equivalent; CI, confidence interval.

PreviousNext
Back to top

In this issue

The Journal of the American Board of Family     Medicine: 34 (1)
The Journal of the American Board of Family Medicine
Vol. 34, Issue 1
January/February 2021
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Mental Health and Benzodiazepine Use Among Patients on Chronic Opioid Therapy
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
1 + 2 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Mental Health and Benzodiazepine Use Among Patients on Chronic Opioid Therapy
Abigail Y. Smith, Julienne K. Kirk, Paul F. Smith, Brian J. Wells
The Journal of the American Board of Family Medicine Jan 2021, 34 (1) 99-104; DOI: 10.3122/jabfm.2021.01.200320

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Mental Health and Benzodiazepine Use Among Patients on Chronic Opioid Therapy
Abigail Y. Smith, Julienne K. Kirk, Paul F. Smith, Brian J. Wells
The Journal of the American Board of Family Medicine Jan 2021, 34 (1) 99-104; DOI: 10.3122/jabfm.2021.01.200320
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Methods
    • Results
    • Discussion
    • Study Limitations
    • Notes
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Advancing Research Methods for Common Problems in Family Medicine and Family Medicine Practice Management
  • Google Scholar

More in this TOC Section

  • Successful Implementation of Integrated Behavioral Health
  • Identifying and Addressing Social Determinants of Health with an Electronic Health Record
  • Integrating Adverse Childhood Experiences and Social Risks Screening in Adult Primary Care
Show more Original Research

Similar Articles

Keywords

  • Benzodiazepines
  • Chronic Disease
  • Electronic Health Records
  • Family Medicine
  • Harm Reduction
  • Morphine
  • Logistic Models
  • Mental Health
  • Opioids
  • Pain Management

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2025 American Board of Family Medicine

Powered by HighWire