Research ArticleOriginal Research

Awareness of Prediabetes Status and Subsequent Health Behavior, Body Weight, and Blood Glucose Levels

Ibiye Owei, Nkiru Umekwe, Fatoumatta Ceesay and Samuel Dagogo-Jack
The Journal of the American Board of Family Medicine January 2019, 32 (1) 20-27; DOI: https://doi.org/10.3122/jabfm.2019.01.180242

Article Figures & Data

Figures

  • Figure 1.
    Figure 1.

    Study design and time intervals of data collection. Prediabetes outcome was assessed after ∼5 years of follow-up of initially normoglycemic POP-ABC participants. Eighteen months later, POP-ABC study participants were rescreened for a newly funded extension PROP-ABC study. The present report compares the 18-month interval changes in glycemic and other measurements between participants who developed prediabetes during POP-ABC study and those who remained normoglycemic.

  • Figure 2.
    Figure 2.

    Interval changes in glycemia in prediabetes and control groups (A) and within the prediabetes group by ethnicity (B), and interval changes in weight (C) and waist circumference (D) in the prediabetes and control groups. There were no significant ethnic differences in the interval changes in glycemia. *P = .006, **P = .001, ***P = .0004, ****P < .0001. To convert the values for glucose to millimoles per liter, multiply by 0.0555. FPG, fasting plasma glucose; PG, plasma glucose.

Tables

  • Table 1.

    Baseline Characteristics of Pathobiology of Prediabetes in a Biracial Cohort Study Participants Who Subsequently Developed Incident Prediabetes or Maintained Normoglycemia (Control) during ∼5 Years of Follow-up*

    CharacteristicsPrediabetesControlP Value
    Number7373
    Age (yr)48.7 ± 0.9648.3 ± 1.06.37
    Women/Men46/2748/25.85
    Black/White36/3735/38.84
    Weight (kg)88.7 ± 2.0283.5 ± 2.19.09
    BMI (kg/m2)31.1 ± 0.7029.2 ± 0.69.04
    Waist circumference (cm)97.9 ± 1.3493.0 ± 1.71.02
    FPG94.4 ± 0.6091.5 ± 0.72.002
    2 hrPG128 ± 2.80120 ± 2.91.05

    • ↵* Data are mean ± SEM FPG, fasting plasma glucose; 2 hrPG, plasma glucose value at 2 hours during oral glucose tolerance test. To convert the values for glucose to millimoles per liter, multiply by 0.0555.

    • BMI, body mass index; FPG, fasting plasma glucose; PG, plasma glucose.

  • Table 2.

    Interval Changes in Glycemic, Anthropometric and Behavioral Measures in Subjects with Incident Prediabetes or Normoglycemia (Control)*

    MeasuresPrediabetesControlP Value
    FPG (mg/dL)−8.01 ± 1.11−2.02 ± 0.64<.0001
    2 hrPG (mg/dL)−8.21 ± 3.348.53 ± 3.17.0004
    Weight (kg)−0.54 ± 0.722.77 ± 1.25.006
    BMI (kg/m2)0.23 ± 0.291.06 ± 0.46.03
    Waist (cm)−1.07 ± 0.781.78 ± 0.85.001
    FHQ score−0.23 ± 0.05−0.16 ± 0.04.002
    MAQ (MET-hr/wk)2.70 ± 3.45−3.30 ± 4.20.03

    • ↵* Data are mean ± SEM FPG, fasting plasma glucose; 2 hrPG, plasma glucose value at 2 hours during oral glucose tolerance test. To convert the values for glucose to millimoles per liter, multiply by 0.0555.

    • BMI, body mass index; FHQ, Food Habits Questionnaire; FPG, fasting plasma glucose; MAQ, Modifiable Activity Questionnaire; MET, metabolic equivalent; PG, plasma glucose.

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