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Research ArticleOriginal Research

Warning Symptoms and Family History in Children and Young Adults with Sudden Cardiac Arrest

Jonathan A. Drezner, Jessie Fudge, Kimberly G. Harmon, Stuart Berger, Robert M. Campbell and Victoria L. Vetter
The Journal of the American Board of Family Medicine July 2012, 25 (4) 408-415; DOI: https://doi.org/10.3122/jabfm.2012.04.110225
Jonathan A. Drezner
MD
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Jessie Fudge
MD
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Kimberly G. Harmon
MD
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Stuart Berger
MD
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Robert M. Campbell
MD
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Victoria L. Vetter
MD
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    Figure 1.

    Diagnostic evaluation after sudden cardiac arrest.

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    Table 1. Study Population Demographics: 79 Children and Young Adults with Sudden Cardiac Arrest
    Characteristic
    Age, years
        5–107 (9)
        11–1527 (34)
        16–2036 (46)
        21–256 (8)
        26–303 (4)
    Race
        White69 (87)
        African American5 (6)
        Hispanic5 (6)
    Sex
        Male54 (68)
        Female25 (32)
    Relation to exercise
        During or within 1 hour of exercise38 (48)
        Unrelated to exercise41 (52)
    • Values provided as n (%).

    • View popup
    Table 2. Causes of Sudden Cardiac Arrest in Study Population
    Diagnosis
    Autopsy negative sudden unexplained death19 (24)
    Hypertrophic cardiomyopathy18 (23)
    Long QT syndrome8 (11)
    Unknown, no autopsy9 (11)
    Anomalous coronary artery4 (5)
    Dilated cardiomyopathy4 (5)
    Arrhythmogenic right ventricular cardiomyopathy3 (4)
    Myocarditis3 (4)
    Wolff–Parkinson–White syndrome2 (3)
    Mitral valve prolapse2 (3)
    Cardiomyopathy, not otherwise specified2 (3)
    Supraventricular tachycardia1 (1)
    Primary pulmonary hypertension1 (1)
    Left ventricular hypertrophy1 (1)
    Coronary artery disease1 (1)
    Marfan syndrome1 (1)
    • Values provided as n (%).

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    Table 3. Reported Symptom Prevalence in Children and Young Adults with Sudden Cardiac Arrest (SCA)*
    SymptomStudy Population with Symptom (%)SCA Victims with Symptoms before Their Most Recent Physician Visit (%)Events, n (range)Symptom Onset before SCA (months)
    Fatigue4425NA21
    Near-syncope/lightheadedness3022NA30
    Chest pain/discomfort2820NA26
    Palpitations2817NA25
    Heart murmur24—NA89
    Shortness of breath2320NA19
    Tire more easily than friends22—NANA
    Syncope18142.3 (2–5)47
    Unexplained seizure activity13112.9 (1–10)71
    Decrease in physical activity11—NANA
    Hypertension3—NA25
    One of the above symptoms7251——
    • ↵* Timing of symptoms related to most recent physician visit and SCA is provided.

    • NA, not applicable.

    • View popup
    Table 4. Reported Family History of Children and Young Adults with Sudden Cardiac Arrest
    Family History
    Died of cardiac disease before age 50 years21 (27)
    Coronary artery disease18 (23)
    Mitral valve prolapse12 (15)
    Cardiac pacemaker12 (15)
    Unexplained fainting11 (14)
    Unexplained seizure diagnosis4 (5)
    Drowning or near drowning event4 (5)
    Wolff–Parkinson–White syndrome3 (4)
    Implanted Cardiac defibrillator1 (<1)
    Hypertrophic cardiomyopathy1 (<1)
    Long QT syndrome1 (<1)
    Dilated cardiomyopathy1 (<1)
    Anomalous coronary artery1 (<1)
    Aortic rupture/Marfan's syndrome1 (<1)
    At least one of the above family history components32 (40)
    • Values provided as n (%).

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The Journal of the American Board of Family     Medicine: 25 (4)
The Journal of the American Board of Family Medicine
Vol. 25, Issue 4
July-August 2012
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Warning Symptoms and Family History in Children and Young Adults with Sudden Cardiac Arrest
Jonathan A. Drezner, Jessie Fudge, Kimberly G. Harmon, Stuart Berger, Robert M. Campbell, Victoria L. Vetter
The Journal of the American Board of Family Medicine Jul 2012, 25 (4) 408-415; DOI: 10.3122/jabfm.2012.04.110225

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Warning Symptoms and Family History in Children and Young Adults with Sudden Cardiac Arrest
Jonathan A. Drezner, Jessie Fudge, Kimberly G. Harmon, Stuart Berger, Robert M. Campbell, Victoria L. Vetter
The Journal of the American Board of Family Medicine Jul 2012, 25 (4) 408-415; DOI: 10.3122/jabfm.2012.04.110225
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