Article Figures & Data
Tables
Unweighted N 8,270 Weighted N 176,423,413 Ferritin Elevated 10.8 Normal 89.2 Uric acid Elevated 17.6 Normal 82.4 Joint pain Yes 44.8 No 55.2 Age (years) 20–44 50.9 45–64 32.8 ≥65 16.3 Sex Male 48.1 Female 51.9 Race/ethnicity Non-Hispanic white 72.6 Non-Hispanic black 10.0 Mexican American 7.0 Other Hispanic 6.9 Other race 3.4 Values presentence as percents.
High Ferritin Low Ferritin P Uric acid (mean mg/dL) 6.15 5.27 <.01 ALT (mean U/L) 39.46 24.47 <.01 AST (mean U/L) 32.65 23.50 <.01 GGT (mean U/L) 55.77 27.58 <.01 Albumin-creatinine ratio ≥30 (%) 16.60 8.75 <.01 Difficulty stooping (%) 24.13 17.29 <.01 Difficulty walking (%) 5.23 3.18 .01 Difficulty standing (%) 11.74 8.08 <.01 Arthritis (%) 28.79 20.82 <.01 Joint pain (%) 47.18 44.46 .33 * High ferritin: >300 ng/mL for men, >200 ng/mL for women.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase.
High Uric Acid Low Uric Acid P Ferritin (mean ng/mL) 181.66 116.66 <.01 ALT (mean U/L) 34.24 24.36 <.01 AST (mean U/L) 29.16 23.49 <.01 GGT (mean U/L) 42.57 28.09 <.01 Albumin-creatinine ratio ≥30 (%) 16.47 8.14 <.01 Difficulty stooping (%) 27.49 16.02 <.01 Difficulty walking (%) 7.00 2.64 <.01 Difficulty standing (%) 15.31 7.02 <.01 Arthritis (%) 31.84 19.52 <.01 Joint pain (%) 52.04 43.21 <.01 * High uric acid: >7 mg/dL for men, >6 mg/dL for women.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase.
- Table 4.
Logistic Regressions Using Combinations of Arthritis, Joint Pain, and Physical Functioning with Uric Acid to Determine the Likelihood of Elevated Ferritin1,2,3
Uric Acid Arthritis or Activity Limitation Odds Ratio (95% CI) Low Stooping normal 1.00 Low Stooping difficult 1.07 (0.84–1.38) High Stooping normal 2.54 (2.01–3.22) High Stooping difficult 1.57 (1.12–2.19) Low Walking normal 1.00 Low Walking difficult 1.04 (0.65–1.67) High Walking normal 2.19 (1.78–2.69) High Walking difficult 2.26 (1.25–4.08) Low Standing normal 1.00 Low Standing difficult 1.19 (0.86–1.64) High Standing normal 2.44 (1.97–3.03) High Standing difficult 1.30 (0.83–2.03) Low No arthritis 1.00 Low Arthritis 1.16 (0.92–1.48) High No arthritis 2.50 (1.97–3.19) High Arthritis 1.88 (1.35–2.62) Low No joint pain 1.00 Low Joint pain 1.04 (0.84–1.28) High No joint pain 2.48 (1.88–3.27) High Joint pain 2.00 (1.51–2.66) High uric acid: >7 mg/dL for men, >6 mg/dL for women. High ferritin: >300 ng/mL for men, >200 ng/mL for women. Adjusted for age, sex, race/ethnicity, kidney condition, liver condition, and alcohol consumption.
Low Uric Acid High Uric Acid Low Ferritin High Ferritin Low Ferritin High Ferritin ALT (U/L) 23.7 31.6 28.8 54.9† AST (U/L) 23.0 28.6 26.1 40.7† GGT (U/L) 26.2 48.0 35.1 71.1† * Adjusted for age, sex, race/ethnicity, kidney condition, liver condition, and alcohol consumption.
† Significantly different (P < .05) from each of the other 3 categories.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase.
