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Research ArticleOriginal Research

Observational Study of Buprenorphine Treatment of Opioid-Dependent Pregnant Women in a Family Medicine Residency: Reports on Maternal and Infant Outcomes

Alane O'Connor, William Alto, Katje Musgrave, Daniel Gibbons, Lalaine Llanto, Selma Holden and Jonathan Karnes
The Journal of the American Board of Family Medicine March 2011, 24 (2) 194-201; DOI: https://doi.org/10.3122/jabfm.2011.02.100155
Alane O'Connor
DNP
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William Alto
MD, MPH
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Katje Musgrave
DO
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Daniel Gibbons
DO
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Lalaine Llanto
MD
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Selma Holden
MD
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Jonathan Karnes
MD
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    Figure 1.

    Relationship between NAS severity and time to peak NAS score.

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    Table 1.

    Characteristics of Maternal and Infant Populations

    Birth Weight (g)Maternal Daily Dose of Buprenorphine at Delivery (mg)NAS Severity (Peak NAS Score)Required Treatment for NASDays in HospitalTime to First Peak NAS Score (hr)Tobacco Use during Pregnancy
    25251610No8103.5Yes
    2772105No765Yes
    3745245No616No
    31101610No7105Yes
    29291213No6104Yes
    348748No694.3Yes
    30251214Yes9143.3Yes
    3515611No1041Yes
    31701612Yes*38No
    3855248No71Yes
    3115168No688.3Yes
    3025129No611.3Yes
    35301614Yes1336Yes
    308084No652Yes
    23201611Yes771Yes
    34551216Yes*39Yes
    28851619Yes11114Yes
    2778618Yes1638Yes
    28701611No669.3Yes
    3415129No686No
    42951610No629.3No
    2400166No558Yes
    309539Yes7120Yes
    Mean (SD)3148 (471.0)13.3 (5.4)10.4 (3.9)7.7 (2.7)66.2 (38.4)
    • ↵* Infants were transferred to another hospital; these infants are not included in mean number (SD) of days in hospital.

    • NAS, neonatal abstinence syndrome.

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The Journal of the American Board of Family     Medicine: 24 (2)
The Journal of the American Board of Family Medicine
Vol. 24, Issue 2
March-April 2011
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Observational Study of Buprenorphine Treatment of Opioid-Dependent Pregnant Women in a Family Medicine Residency: Reports on Maternal and Infant Outcomes
Alane O'Connor, William Alto, Katje Musgrave, Daniel Gibbons, Lalaine Llanto, Selma Holden, Jonathan Karnes
The Journal of the American Board of Family Medicine Mar 2011, 24 (2) 194-201; DOI: 10.3122/jabfm.2011.02.100155

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Observational Study of Buprenorphine Treatment of Opioid-Dependent Pregnant Women in a Family Medicine Residency: Reports on Maternal and Infant Outcomes
Alane O'Connor, William Alto, Katje Musgrave, Daniel Gibbons, Lalaine Llanto, Selma Holden, Jonathan Karnes
The Journal of the American Board of Family Medicine Mar 2011, 24 (2) 194-201; DOI: 10.3122/jabfm.2011.02.100155
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