Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Abstracts In Press
    • Archives
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Abstracts In Press
    • Archives
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM on Bluesky
  • JABFM On Facebook
  • JABFM On Twitter
  • JABFM On YouTube
Research ArticleOriginal Research

Acanthosis Nigricans: High Prevalence and Association with Diabetes in a Practice-based Research Network Consortium—A PRImary care Multi-Ethnic Network (PRIME Net) Study

Alberta S. Kong, Robert L. Williams, Robert Rhyne, Virginia Urias-Sandoval, Gina Cardinali, Nancy F. Weller, Betty Skipper, Robert Volk, Elvan Daniels, Bennett Parnes, Laurie McPherson and ; on behalf of PRIME Net Clinicians
The Journal of the American Board of Family Medicine July 2010, 23 (4) 476-485; DOI: https://doi.org/10.3122/jabfm.2010.04.090221
Alberta S. Kong
MD, MPH
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert L. Williams
MD, MPH
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert Rhyne
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Virginia Urias-Sandoval
BA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gina Cardinali
MSW
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nancy F. Weller
DrPH
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Betty Skipper
PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert Volk
PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elvan Daniels
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bennett Parnes
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laurie McPherson
MSCIS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. ↵
    Knowler W, Barrett-Connor E, Fowler S, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393–403.
    OpenUrlCrossRefPubMedWeb of Science
  2. ↵
    Drobac S, Brickman W, Smith T, Binns HJ. Evaluation of a type 2 diabetes screening protocol in an urban pediatric clinic. Pediatrics 2004; 114: 141–8.
    OpenUrlAbstract/FREE Full Text
  3. ↵
    Hud JA Jr, Cohen JB, Wagner JM, Cruz PD Jr. Prevalence and significance of acanthosis nigricans in an adult obese population. Arch Dermatol 1992; 128: 941–4.
    OpenUrlCrossRefPubMedWeb of Science
  4. ↵
    Kobaissi HA, Weigensberg MJ, Ball GD, Cruz ML, Shaibi GQ, Goran MI. Relation between acanthosis nigricans and insulin sensitivity in overweight Hispanic children at risk for type 2 diabetes. Diabetes Care 2004; 27: 1412–6.
    OpenUrlAbstract/FREE Full Text
  5. Litonjua P, Pinero-Pilona A, Aviles-Santa L, Raskin P. Prevalence of acanthosis nigricans in newly diagnosed type 2 diabetes. Endocr Pract 2004; 10: 101–6.
    OpenUrlPubMed
  6. ↵
    Mukhtar Q, Cleverley G, Voorhees RE, McGrath JW. Prevalence of acanthosis nigricans and its association with hyperinsulinemia in New Mexico adolescents. J Adolesc Health 2001; 28: 372–6.
    OpenUrlCrossRefPubMedWeb of Science
  7. Stoddart ML, Blevins KS, Lee ET, Wang W, Blackett PR. Association of acanthosis nigricans with hyperinsulinemia compared with other selected risk factors for type 2 diabetes in Cherokee Indians: the Cherokee Diabetes Study. Diabetes Care 2002; 25: 1009–14.
    OpenUrlAbstract/FREE Full Text
  8. Stuart CA, Pate CJ, Peters EJ. Prevalence of acanthosis nigricans in an unselected population. Am J Med 1989; 87: 269–72.
    OpenUrlPubMedWeb of Science
  9. Stuart CA, Smith MM, Gilkison CR, Shaheb S, Stahn RM. Acanthosis Nigricans among Native Americans: an indicator of high diabetes risk. Am J Public Health 1994; 84: 1839–42.
    OpenUrlPubMedWeb of Science
  10. ↵
    Burke JP, Hale DE, Hazuda HP, Stern MP. A quantitative scale of acanthosis nigricans. Diabetes Care 1999; 22: 1655–9.
    OpenUrlAbstract/FREE Full Text
  11. ↵
    Stuart CA, Gilkison CR, Smith MM, Bosma AM, Keenan BS, Nagamani M. Acanthosis nigricans as a risk factor for non-insulin dependent diabetes mellitus. Clin Pediatr (Phila) 1998; 37: 73–9.
    OpenUrlAbstract/FREE Full Text
  12. ↵
    Kong A, Williams R, Smith M, et al. Acanthosis nigricans and diabetes risk factors: prevalence in young persons seen in Southwestern US primary care practices. Ann Fam Med 2007; 5: 202–8.
    OpenUrlAbstract/FREE Full Text
  13. ↵
    Brickman W, Binns HJ, Jovanovic B, Kolesky S, Mancini A, Metzger B. Acanthosis nigricans: a common finding in overweight youth. Pediatr Dermatol 2007; 24: 601–6.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    University of New Mexico Health Sciences Center. Primary Care Multiethnic Network [homepage]. Available at http://hsc.unm.edu/som/primenet/. Accessed 15 May 2010.
  15. ↵
    Binns HJ, Lanier D, Pace WD, et al. Describing primary care encounters: the Primary Care Network Survey and the National Ambulatory Medical Care Survey. Ann Fam Med 2007; 5: 39–47.
    OpenUrlAbstract/FREE Full Text
  16. ↵
    University of New Mexico Health Sciences Center. Appendix 9. Diabetes Health History Survey. Available at http://hsc.unm.edu/som/primenet/documents/pdf/AN_Health_History_survey.pdf. Accessed 15 May 2010.
  17. ↵
    Williams R, McPherson L, Kong A, Skipper B, Weller N. Internet-based training in a practice-based research network consortium: a report from the Primary Care Multiethnic Network (PRIME Net). J Am Board Fam Med 2009; 22: 446–52.
    OpenUrlAbstract/FREE Full Text
  18. ↵
    University of New Mexico Health Sciences Center. PRIME-Net Acanthosis nigricans CME. Available at http://hsc.unm.edu/som/primenet/an_cme.shtml. Accessed 15 May 2010.
  19. ↵
    Spiegelman D, Hertzmark E. Easy SAS calculations for risk or prevalence ratios and differences. Am J Epidemiol 2005; 162: 199–200.
    OpenUrlFREE Full Text
  20. ↵
    Copeland K, Pankratz K, Cathey V, et al. Acanthosis nigricans, insulin resistance (HOMA) and dyslipidemia among Native American children. J Okla State Med Assoc 2006; 99: 19–24.
    OpenUrlPubMed
  21. Yamazaki H, Ito S, Yoshida H. Acanthosis nigricans is a reliable cutaneous marker of insulin resistance in obese Japanese children. Pediatr Int 2003; 45: 701–5.
    OpenUrlCrossRefPubMedWeb of Science
  22. ↵
    Bonet B, Viana M, Sanchez-Vera I, Quintanar A, Martinez J, Espino M. Adipose tissue and liver lipid metabolism in obese children: role of the body mass index and the presence of acanthosis nigricans. Diabet Med 2007; 24: 1190–8.
    OpenUrl
  23. ↵
    Guran T, Turan S, Akcay T, Bereket A. Significance of acanthosis nigricans in childhood obesity. J Paediatr Child Health 2008; 44: 338–41.
    OpenUrlCrossRefPubMedWeb of Science
  24. ↵
    Fareau G, Maldonado M, Oral E, Balasubramanyam A. Regression of acanthosis nigricans correlates with disappearance of anti-insulin receptor autoantibodies and achievement of euglycemia in type B insulin resistance syndrome. Metabolism 2006; 56: 670–5.
    OpenUrl
  25. ↵
    Romo A, Benavides S. Treatment options in insulin resistance obesity-related acanthosis nigricans. Ann Pharmacother 2008; 42: 1090–4.
    OpenUrlCrossRefPubMed
  26. ↵
    Sloane PD, Dolor RJ, Halladay J. Increasing the role of practice networks in medical research. J Am Board Fam Med 2009; 22: 348–51.
    OpenUrlFREE Full Text
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family Medicine: 23 (4)
The Journal of the American Board of Family Medicine
Vol. 23, Issue 4
July-August 2010
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Acanthosis Nigricans: High Prevalence and Association with Diabetes in a Practice-based Research Network Consortium—A PRImary care Multi-Ethnic Network (PRIME Net) Study
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
3 + 6 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Acanthosis Nigricans: High Prevalence and Association with Diabetes in a Practice-based Research Network Consortium—A PRImary care Multi-Ethnic Network (PRIME Net) Study
Alberta S. Kong, Robert L. Williams, Robert Rhyne, Virginia Urias-Sandoval, Gina Cardinali, Nancy F. Weller, Betty Skipper, Robert Volk, Elvan Daniels, Bennett Parnes, Laurie McPherson
The Journal of the American Board of Family Medicine Jul 2010, 23 (4) 476-485; DOI: 10.3122/jabfm.2010.04.090221

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Acanthosis Nigricans: High Prevalence and Association with Diabetes in a Practice-based Research Network Consortium—A PRImary care Multi-Ethnic Network (PRIME Net) Study
Alberta S. Kong, Robert L. Williams, Robert Rhyne, Virginia Urias-Sandoval, Gina Cardinali, Nancy F. Weller, Betty Skipper, Robert Volk, Elvan Daniels, Bennett Parnes, Laurie McPherson
The Journal of the American Board of Family Medicine Jul 2010, 23 (4) 476-485; DOI: 10.3122/jabfm.2010.04.090221
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Notes
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • Guest Family Physician Commentaries
  • PubMed
  • Google Scholar

Cited By...

  • Single-centre case-control study investigating the association between acanthosis nigricans, insulin resistance and type 2 diabetes in a young, overweight, UK population
  • Cultivating a Cycle of Trust With Diverse Communities in Practice-Based Research: A Report From PRIME Net
  • Reports of Persistent Change in the Clinical Encounter Following Research Participation: A Report From the Primary Care Multiethnic Network (PRIME Net)
  • Card Studies for Observational Research in Practice
  • Guest Family Physician Commentaries
  • Google Scholar

More in this TOC Section

  • Identifying and Addressing Social Determinants of Health with an Electronic Health Record
  • Integrating Adverse Childhood Experiences and Social Risks Screening in Adult Primary Care
  • A Pilot Comparison of Clinical Data Collection Methods Using Paper, Electronic Health Record Prompt, and a Smartphone Application
Show more Original Research

Similar Articles

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2025 American Board of Family Medicine

Powered by HighWire