Article Figures & Data
Tables
Preparation Dose Comments Just D by Sunlight vitamins 400 IU in 1 mL Carson labs 400 IU gelcap Polyvisol 400 IU Also contains other vitamins Causes Example Reduced skin synthesis Sunscreen, skin pigment, season/latitude/time of day, aging, skin grafts Decreaseed absorption Cystic fibrosis, celiac disease, whipple disease, Crohn disease, gastric bypass, medications that reduce cholesterol absorption Increased sesquestration Obesity Increased catabolism Anticonvulsant, glucocorticoid, highly active antiretroviral treatment, and some immunosuppressants Breastfeeding Decreased synthesis of 25-hydroxyvitamin D Hepatic failure Increased urinary loss of 25-hydroxyvitamin D Nephrotic proteinuria Decreased synthesis of 1,25-dihydroxyvitamin D Chronic renal failure Heritable disorders Genetic mutations causing rickets, or vitamin D resistance Acquired disorders Tumor-induced osteomalacia, primary hyperparathyroidism, hyperthyroidism, granulomatous disorders such as sarcoidosis, tuburculosis, and some lymphomas
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