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Research ArticleOriginal Research

Variability of Vaginal pH Determination by Patients and Clinicians

Daron G. Ferris, Sean L. Francis, Eileen D. Dickman, Kimberly Miler-Miles, Jennifer L. Waller and Nora McClendon
The Journal of the American Board of Family Medicine July 2006, 19 (4) 368-373; DOI: https://doi.org/10.3122/jabfm.19.4.368
Daron G. Ferris
MD
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Sean L. Francis
MD
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Eileen D. Dickman
PhD, MBA, CCRC
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Kimberly Miler-Miles
MD
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Jennifer L. Waller
PhD
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Nora McClendon
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    Figure 1.

    Bland-Altman plot for differences in swab pH as determined by subjects and the clinician. pH values had minimal variability between observers.

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    Table 1.

    Demographic Statistics (n = 113)

    Variable
    Race (n, %)
        Black53(46.9)
        White55(48.7)
        Asian0(0.0)
        Hispanic3(2.7)
        Other2(1.8)
    Age (mean, SD)*35.1(10.1)
    Height (mean, SD)†64.7(3.2)
    Weight (mean, SD)171.8(45.3)
    Gravida (mean, SD)2.0(1.7)
    Parity (mean, SD)1.7(1.5)
    Abortion (mean, SD)0.3(0.7)
    Vaginal births (mean, SD)1.5(1.5)
    Cesarean sections (mean, SD)0.3(0.7)
    Regular periods (n, %)78(69.0)
    Pelvic surgery (n, %)28(24.8)
    Vaginal medications (n, %)1(0.9)
    Hormone replacement therapy (n, %)11(9.7)
    Birth control method (n, %)
        None36(31.9)
        Surgical27(23.9)
        Other‡50(44.3)
    • * Height in inches.

    • † Weight in pounds.

    • ‡ Includes birth control pills, barrier methods, progesterone injection, transdermal, intrauterine device, and abstinence.

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    Table 2.

    Comparison of Samplers and Intravaginal pH Sampling Methods

    Swab-based pH testMean pHSDMedian pHICC*SP Value
    Subject4.50.54.50.74−538.0.0001
    Clinician4.70.54.6
    • * ICC, interclass correlation coefficients; S, Wilcoxon’s signed rank test.

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    Table 3.

    Mixed Model Analyses for Differences of Intravaginal pH in 3 Regions of the Vagina

    ModelAdjusted Least SquareF ValueP Value
    MeanSE
    Unadjusted model
        Vaginal area0.84.43
            Proximal4.600.07
            Middle4.520.05
            Distal4.540.04
    Full model
        Age1.22.27
        Parity7.04.01
        Race3.47.02
        Hormone replacement therapy1.06.31
        Birth control3.29.07
        Vaginal area0.61.54
            Proximal4.590.12
            Middle4.530.11
            Distal4.530.11
    Final model
        Parity10.40.002
        Race4.17.008
        Vaginal area0.61.54
            Proximal4.610.11
            Middle4.550.09
            Distal4.550.09
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The Journal of the American Board of Family Medicine: 19 (4)
The Journal of the American Board of Family Medicine
Vol. 19, Issue 4
July-August 2006
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Variability of Vaginal pH Determination by Patients and Clinicians
Daron G. Ferris, Sean L. Francis, Eileen D. Dickman, Kimberly Miler-Miles, Jennifer L. Waller, Nora McClendon
The Journal of the American Board of Family Medicine Jul 2006, 19 (4) 368-373; DOI: 10.3122/jabfm.19.4.368

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Variability of Vaginal pH Determination by Patients and Clinicians
Daron G. Ferris, Sean L. Francis, Eileen D. Dickman, Kimberly Miler-Miles, Jennifer L. Waller, Nora McClendon
The Journal of the American Board of Family Medicine Jul 2006, 19 (4) 368-373; DOI: 10.3122/jabfm.19.4.368
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