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Research ArticleOriginal Research

Diabetes Mellitus, Smoking, and the Risk for Asymptomatic Peripheral Arterial Disease: Whom Should We Screen?

Sharon L. Eason, Nancy J. Petersen, Maria Suarez-Almazor, Barry Davis and Tracie C. Collins
The Journal of the American Board of Family Practice September 2005, 18 (5) 355-361; DOI: https://doi.org/10.3122/jabfm.18.5.355
Sharon L. Eason
MPH
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Nancy J. Petersen
PhD
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Maria Suarez-Almazor
MD, PhD
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Barry Davis
MD, PhD
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Tracie C. Collins
MD, MPH
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    Figure 1.

    Individual and synergistic associations of diabetes and heavy smoking with asymptomatic PAD.

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    Table 1.

    General Characteristics of the Study Population

    Without PAD* (n = 341) N (%)With Asymptomatic PAD (n = 25) N (%)P Value
    Gender, no.
        Male159 (47)15 (60).30
        Female177 (53)10 (40)
    Race/ethnicity
        White121 (93)9 (36).66
        African American106 (92)9 (36)
        Hispanic114 (94)7 (28)
    Comorbidities
        Hypertension226 (66)20 (80).19
        Congestive heart failure15 (5)3 (12).11
        Diabetes116 (34)16 (64).00
    Mean age in years (SD)63.54 (7.3)64.56 (6.4).62
    Age range in years50–9050–74
    • * PAD, peripheral arterial disease.

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    Table 2.

    Lifestyle and Clinical Survey

    Without PAD* N (%)With Asymptomatic PAD N (%)P ValueTotal
    Have you smoked at least 100 cigarettes in your entire life?
        Yes183 (54)15 (60).55198 (54)
        No157 (46)10 (40)167 (46)
    If you smoke, how many cigarettes have you smoked per day?
        1 pack or less133 (72)10 (67).03143 (71)
        >1 pack53 (28)5 (33)58 (29)
    How many years have you been a regular smoker?
        0 years197 (58)13 (52).84
        <1 year to 40 years75 (22)6 (24)
        >40 years69 (20)6 (24)
    Do you drink alcoholic beverages?
        Yes119 (35)4 (16).05123 (34)
        No222 (65)21 (84)243 (66)
    How often do you consume alcohol?
        Some23 (19)1 (25).6424 (19)
        Weekly63 (52)2 (50)65 (52)
        Daily35 (29)1 (25)36 (29)
    How often do you walk for at least 10 minutes without stopping?
        Rarely or never96 (28)12 (48).31107 (30)
        Once/week or more245 (72)13 (52)258 (70)
    • * PAD, peripheral arterial disease.

    • View popup
    Table 3.

    Predicting Asymptomatic PAD*

    Sensitivity (%)†Specificity (%)‡PVP (%)§PVN (%)‖
    Diabetes64661296
    Smoke3446894
    Both diabetes/smoke20921594
    Neither diabetes/smoke855189
    • * PAD, peripheral arterial disease.

    • † Sensitivity, the probability of a positive test result in patients with asymptomatic PAD.

    • ‡ Specificity, the probability of a negative test result in patients without PAD.

    • § PVP, probability of asymptomatic PAD given a positive test result.

    • ‖ PVN, probability of no PAD given a negative test result.

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The Journal of the American Board of Family Practice: 18 (5)
The Journal of the American Board of Family Practice
Vol. 18, Issue 5
1 Sep 2005
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Diabetes Mellitus, Smoking, and the Risk for Asymptomatic Peripheral Arterial Disease: Whom Should We Screen?
Sharon L. Eason, Nancy J. Petersen, Maria Suarez-Almazor, Barry Davis, Tracie C. Collins
The Journal of the American Board of Family Practice Sep 2005, 18 (5) 355-361; DOI: 10.3122/jabfm.18.5.355

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Diabetes Mellitus, Smoking, and the Risk for Asymptomatic Peripheral Arterial Disease: Whom Should We Screen?
Sharon L. Eason, Nancy J. Petersen, Maria Suarez-Almazor, Barry Davis, Tracie C. Collins
The Journal of the American Board of Family Practice Sep 2005, 18 (5) 355-361; DOI: 10.3122/jabfm.18.5.355
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