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Case ReportCase Report

Unraveling The Mysteries Of Serum Theophylline Levels: A Patient Care Report In The Light Of Pharmacokinetics

Henry Bussey, Christine Quandt, Raylene Rospond and Winnie Loesch
The Journal of the American Board of Family Practice October 1988, 1 (4) 282-287; DOI: https://doi.org/10.3122/jabfm.1.4.282
Henry Bussey
From the Departments of Pharmacology and Family Practice, the University of Texas Health Science Center at San Antonio and the College of Pharmacy, the University of Texas at Austin. Address reprint requests to Henry Bussey, Pharm.D., Clinical Pharmacy Programs, 7703 Floyd Curl Drive, San Antonio, TX 78284-7765.
Pharm.D.
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Christine Quandt
From the Departments of Pharmacology and Family Practice, the University of Texas Health Science Center at San Antonio and the College of Pharmacy, the University of Texas at Austin. Address reprint requests to Henry Bussey, Pharm.D., Clinical Pharmacy Programs, 7703 Floyd Curl Drive, San Antonio, TX 78284-7765.
Pharm.D.
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Raylene Rospond
From the Departments of Pharmacology and Family Practice, the University of Texas Health Science Center at San Antonio and the College of Pharmacy, the University of Texas at Austin. Address reprint requests to Henry Bussey, Pharm.D., Clinical Pharmacy Programs, 7703 Floyd Curl Drive, San Antonio, TX 78284-7765.
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Winnie Loesch
From the Departments of Pharmacology and Family Practice, the University of Texas Health Science Center at San Antonio and the College of Pharmacy, the University of Texas at Austin. Address reprint requests to Henry Bussey, Pharm.D., Clinical Pharmacy Programs, 7703 Floyd Curl Drive, San Antonio, TX 78284-7765.
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  • Correction - July 01, 1989

Abstract

One of our patients had trouble maintaining therapeutic and safe levels of theophylline, even though we were careful in planning and monitoring her drug regimen. This case report shows how we were able to use principles of pharmacokinetics to distinguish among plausible explanations for her experience. We discovered that she was not taking the drug consistently as prescribed and that supervised administration resolved apparent contradictions between doses and serum levels. We believe that physicians can use the same information and methods that we used to get better and safer results from theophylline therapy.

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The Journal of the American Board of Family     Practice: 1 (4)
The Journal of the American Board of Family Practice
Vol. 1, Issue 4
1 Oct 1988
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Unraveling The Mysteries Of Serum Theophylline Levels: A Patient Care Report In The Light Of Pharmacokinetics
Henry Bussey, Christine Quandt, Raylene Rospond, Winnie Loesch
The Journal of the American Board of Family Practice Oct 1988, 1 (4) 282-287; DOI: 10.3122/jabfm.1.4.282

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Unraveling The Mysteries Of Serum Theophylline Levels: A Patient Care Report In The Light Of Pharmacokinetics
Henry Bussey, Christine Quandt, Raylene Rospond, Winnie Loesch
The Journal of the American Board of Family Practice Oct 1988, 1 (4) 282-287; DOI: 10.3122/jabfm.1.4.282
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