Filtering Race Out of GFR Calculation

Winfred Frazier; Yufei Ge

doi:10.3122/jabfm.2024.240035R0

Research ArticlePRIORITY UPDATES FROM THE RESEARCH LITERATURE (PURLs)

Filtering Race Out of GFR Calculation

Winfred Frazier, Yufei Ge, Carina Brown and Greg Castelli

The Journal of the American Board of Family Medicine January 2025, jabfm.2024.240035R0; DOI: https://doi.org/10.3122/jabfm.2024.240035R0

Winfred Frazier

From the UPMC St. Margaret Family Medicine Residency Program, Pittsburgh, PA (WF, YG).

MD, MPH

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Yufei Ge

From the UPMC St. Margaret Family Medicine Residency Program, Pittsburgh, PA (WF, YG).

MD, MS

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Carina Brown

Roles: FPIN Editor:

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Greg Castelli

PharmD

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2009 CKD-EPI Creatinine Calculator²
Factors Patient A Patient B
Sex Female Female
Age (years) 55 55
Black Race Yes No
Serum Creatinine (mg/dL): 2.8 2.8
eGFR (mL/min/1.73m²): 21 18

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Table 1.

eGFR Equations

Equation	Year Developed	Filtration Markers	Demographic Variables
eGFRcr[ASR]	2009	creatinine	age, sex, race
eGFRcr[AS]	2021	creatinine	age, sex
eGFRcys[AS]	2012	cystatin c	age, sex
eGFRcr-cys[AS]	2021	creatinine, cystatin c	age, sex

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The Journal of the American Board of Family Medicine

Vol. 37, Issue 6

November-December 2024

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Filtering Race Out of GFR Calculation

Winfred Frazier, Yufei Ge

The Journal of the American Board of Family Medicine Jan 2025, jabfm.2024.240035R0; DOI: 10.3122/jabfm.2024.240035R0

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Filtering Race Out of GFR Calculation

Winfred Frazier, Yufei Ge

The Journal of the American Board of Family Medicine Jan 2025, jabfm.2024.240035R0; DOI: 10.3122/jabfm.2024.240035R0

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Keywords

Chronic Kidney Disease
Cystatin C
End-Stage Renal Disease
Glomerular Filtration Rate
Serum Creatinine

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Factors	Patient A	Patient B
Sex	Female	Female
Age (years)	55	55
Black Race	Yes	No
Serum Creatinine (mg/dL):	2.8	2.8
eGFR (mL/min/1.73m²):	21	18