Management of Women at High Risk for Breast Cancer

Article Figures & Data

Table 1.

Population Characteristics

	Overall (n = 200)
Age
Mean (SD)	42.8 (4.38)
Median [Min, Max]	43.0 [35.0, 50.0]
Race
Non-white	13 (6.5%)
White	180 (90.0%)
Missing	7 (3.5%)
BMI
Mean (SD)	31.4 (9.48)
Median [Min, Max]	28.8 [18.2, 82.5]
Age of 1^st menses
Mean (SD)	12.6 (1.41)
Median [Min, Max]	12.0 [9.0, 18.0]
Have child(ren)
No	50 (25.0%)
Yes	150 (75.0%)
Age of 1^st birth
29 or younger	94 (47.0%)
30 or older	56 (28.0%)
Has not given birth	50 (25.0%)
Had mammogram
No	60 (30.0%)
Yes	140 (70.0%)
Breast Density
A or B	56 (28.0%)
C or D	83 (41.5%)
Missing	61 (30.5%)
Gone through menopause
No	189 (94.5%)
Yes	11 (5.5%)
Age at menopause
Mean (SD)	40.0 (10.0)
Median [Min, Max]	46.0 [26.0, 50.0]
Missing	189 (94.5%)
Number of 1^st degree relatives with breast cancer
0	150 (80%)
1	50 (20%)
Number of 2^nd degree relatives with breast cancer
0	30 (15%)
1	135 (67.5%)
2	23 (11.5%)
3	11 (5.5%)
4	1 (0.5%)

Table 2.

Estimates of Multivariate and Univariate Logistic Regression Models (n = 200)

Variable	Sub-Category	OR – Multivariate Model (95% CI)	Adjusted p-Value	OR – Univariate Model (95% CI)	Adjusted p-Value
Number of 1^st Degree Relatives with Breast Cancer		8.82 (3.7, 22.91)	<0.001	3.86 (1.99, 7.63)	0.002
Number of 2^nd Degree Relatives with Breast Cancer		2.54 (1.5, 4.52)	0.013	1.3 (0.87, 1.95)	1
Age at 1^st Live Birth	Has not given birth	1 (referent)	0.003	1 (referent)	0.003
	29 or younger	0.32 (0.13, 0.76)		0.41 (0.19, 0.87)
	30 or older	1.94 (0.83, 4.65)		1.82 (0.84, 4.01)