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Research ArticleOriginal Research

Does Clinical Decision Support Increase Appropriate Medication Prescribing for Cardiovascular Risk Reduction?

David Boston, Annie E. Larson, Christina R. Sheppler, Patrick J. O’Connor, JoAnn M. Sperl-Hillen, Jennifer Hauschildt and Rachel Gold
The Journal of the American Board of Family Medicine September 2023, jabfm.2022.220391R2; DOI: https://doi.org/10.3122/jabfm.2022.220391R2
David Boston
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
MD, MS, FACC
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Annie E. Larson
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
PhD
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Christina R. Sheppler
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
PhD
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Patrick J. O’Connor
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
MD, MA, MPH
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JoAnn M. Sperl-Hillen
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
MD
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Jennifer Hauschildt
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
MPH
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Rachel Gold
From the OCHIN Inc., PO Box 5426, Portland, OR (DB, AEL, JH, RG); Kaiser Permanente Northwest, Center for Health Research, 3800 N Interstate Ave, Portland, OR (CRS); HealthPartners Institute, 8170 33rd Ave So 23301a, Minneapolis, MN (PJOC, JMSH).
PhD, MPH
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Article Figures & Data

Figures

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    Figure 1.

    CV Wizard CONSORT flow diagram.

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    Figure 2.

    Predicted probability of receiving a prescription for recommended medication. Abbreviation: CDS, Clinical decision support.

Tables

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    Table 1.

    Encounters with a Recommendation to Start a Hypertension, Diabetes, Statin, or Tobacco Cessation Medication Stratified by Those Where a Prescription Was versus Was Not Written Within 1 Week of Encounter

    All CDS-Eligible Encounters (n = 106,769)Intervention CDS Eligible Encounters (n = 61,219)Control CDS Eligible Encounters (n = 45,550)p-Value
    Encounter Risk
     Avg. Reversible Risk (SD)10.4 (10.3)9.7 (10.2)11.3 (10.5)<0.001
     Avg. 10-Year ASCVD Risk (SD)17.2 (12.8)16.5 (12.5)18.1 (13.0)<0.001
    Average Age at Encounter (SD)58.5 (8.8)58.0 (8.8)59.2 (8.7)<0.001
    Avg # Visits During Study (SD)7.1 (6.2)11.1 (9.8)10.5 (8.7)<0.001
    Gender<0.001
     Woman56,388 (52.2%)33,232 (54.3%)23,156 (50.8%)
    Ethnicity<0.001
     Hispanic27,269 (25.5%)19,615 (32.0%)7654 (16.8%)
     Non-Hispanic75,680 (70.9%)38,854 (63.5%)36,826 (80.9%)
     Unknown Ethnicity3820 (3.6%)2750 (4.5%)7654 (16.8%)
    Race<0.001
     Asian4262 (4.0%)2721 (4.4%)1541 (3.4%)
     Black21,056 (19.7%)13,002 (21.2%)8054 (17.7%)
     Other*3110 (2.9%)2026 (3.3%)1084 (2.4%)
     White70,151 (65.7%)36,810 (60.1%)33,341 (73.2%)
     Unknown8190 (7.7%)6660 (10.9%)1530 (3.4%)
    Insurance at Encounter<0.001
     Medicaid36,451 (34.1%)22,543 (36.8%)13,908 (30.5%)
     Medicare37,270 (34.9%)19,311 (31.5%)17,959 (39.4%)
     Other Public3175 (3.0%)2771 (4.5%)404 (0.9%)
     Private14,097 (13.2%)6768 (11.1%)7329 (16.1%)
     Uninsured15,776 (14.8%)9826 (16.1%)5950 (13.1%)
    FPL at Encounter<0.001
     <138%56,554 (53.0%)38,051 (62.2%)18,503 (40.6%)
     ≥138%18,079 (16.9%)12,287 (20.1%)5792 (12.7%)
     Missing32,136 (30.1%)10,881 (17.8%)21,255 (46.7%)
    Avg Appt Length (mins)<0.001
     5 to 15 minutes18,943 (17.7%)12,851 (21.0%)6092 (13.4%)
     ≥20 minutes87,508 (82.0%)48,086 (78.6%)39,422 (86.6%)
     Missing318 (0.3%)282 (0.5%)36 (0.1%)
    Avg Time Behind Schedule (mins)0.272
     ≤10 minutes81,166 (76.0%)46,463 (75.9%)34,703 (76.2%)
    • Abbreviations: CDS, Clinical decision support; SD, Standard deviation; FPL, Federal poverty level; ASCVD, Atherosclerotic cardiovascular disease.

    • *Other race includes American Indian, Alaska Native, Native Hawaiian, Pacific Islander, those who selected more than one race, and all other race.

    • View popup
    Table 2.

    Encounters with a Recommendation to Start a Hypertension, Diabetes, Statin, or Tobacco Cessation Medication Stratified by Those Where a Prescription Was versus Was Not Written Within 1 Week of Encounter

    All Encounters with a Recommendation (n = 106,769)Recommendations with a Prescription Within 1 Week (n = 35,078)Recommendations with No Prescription Within 1 Week (n = 71,691)p-Value
    Group<0.001
     Intervention - CDS Used15.216.214.7
     Intervention - CDS Not Used42.241.242.6
     Control42.742.642.7
    Encounter Risk
     Avg. Reversible Risk (SD)10.4 (10.3)11.5 (11.4)9.8 (9.7)<0.001
     Avg. 10-Year ASCVD Risk (SD)17.2 (12.8)17.9 (13.4)16.8 (12.4)<0.001
    Avg. Age at Encounter, years (SD)58.5 (8.8)57.9 (8.7)58.8 (8.8)<0.001
    Avg. No. Visits During Study (SD)7.1 (6.2)7.1 (5.8)7.1 (6.3)<0.001
    Gender<0.001
     Woman52.251.353.6
    Ethnicity<0.001
     Hispanic25.530.423.2
     Non-Hispanic70.966.273.2
     Unknown Ethnicity3.63.43.7
    Race<0.001
     Asian4.04.43.8
     Black19.723.617.8
     Other*2.92.63.1
     White65.761.267.9
     Unknown7.78.27.4
    Insurance at Encounter<0.001
     Medicaid34.133.534.5
     Medicare34.929.337.7
     Other Public3.03.52.7
     Private13.213.413.1
     Uninsured14.820.312.1
    FPL at Encounter<0.001
     <138%53.055.151.9
     ≥138%16.916.817.0
     Missing30.128.231.0
    Avg Appt Length (mins)<0.001
     5 to 15 minutes17.717.417.9
     ≥20 minutes82.082.281.9
     Missing0.30.40.2
    Avg Time Behind Schedule (mins)0.024
     ≤10 minutes76.075.676.2
     >10 minutes24.024.423.8
    • Abbreviations: CDS, Clinical decision support; SD, Standard deviation; FPL, Federal poverty level; ASCVD, Atherosclerotic cardiovascular disease.

    • *Other race includes American Indian, Alaska Native, Native Hawaiian, Pacific Islander, those who selected more than one race, and all other race.

    • View popup
    Table 3.

    Unadjusted Frequency of Provider Action Taken Related to Encounters in Which CDS Recommended New Medication

    Intervention Clinic Encs, Tool Used (CDS+)Intervention Clinic Encs, Tool Not Used (CDS-)Control Clinic Encs (CDSc)
    BP Meds(n = 6820)(n = 18,265)(n = 23,267)
     Any BP Rx Recommendation34.932.733.7
     Recommendation High Priority (1 to 2)40.437.137.4
     Recommendation Low Priority (3 to 6)26.124.625.7
     Between rec p-value<0.001<0.001<0.001
    Diabetes (DM) Meds(n = 1354)(n = 3951)(n = 2994)
     Any DM Rx Recommendation36.034.532.9
     Recommendation High Priority (1 to 2)45.544.843.9
     Recommendation Low Priority (3 to 6)23.518.520.6
     Between rec p-value<0.001<0.001<0.001
    Dyslipidemia Meds(n = 4383)(n = 10,186)(n = 12,704)
     Any Dyslipidemia Rx Recommendation10.36.66.5
     Recommendation High Priority (1 to 2)11.66.96.6
     Recommendation Low Priority (3 to 6)17.014.614.2
     Between rec p-value0.140<0.001<0.001
    Tobacco Cessation Meds(n = 3006)(n = 7110)(n = 9543)
     Any Tobacco Cessation Rx Recommendation9.16.96.7
     Priority 19.47.06.8
     Priority 26.36.05.9
    • Abbreviations: CDS, Clinical decision support; BP, Blood pressure.

    • Notes: N = count of encounters for patients with a recommendation to start a medication who were not prescribed any type of that medication in the past 6 months. Two-tailed, unpaired t test with significance level set at 0.05 assuming unequal variances.

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The Journal of the American Board of Family     Medicine: 37 (6)
The Journal of the American Board of Family Medicine
Vol. 37, Issue 6
November-December 2024
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Does Clinical Decision Support Increase Appropriate Medication Prescribing for Cardiovascular Risk Reduction?
David Boston, Annie E. Larson, Christina R. Sheppler, Patrick J. O’Connor, JoAnn M. Sperl-Hillen, Jennifer Hauschildt, Rachel Gold
The Journal of the American Board of Family Medicine Sep 2023, jabfm.2022.220391R2; DOI: 10.3122/jabfm.2022.220391R2

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Does Clinical Decision Support Increase Appropriate Medication Prescribing for Cardiovascular Risk Reduction?
David Boston, Annie E. Larson, Christina R. Sheppler, Patrick J. O’Connor, JoAnn M. Sperl-Hillen, Jennifer Hauschildt, Rachel Gold
The Journal of the American Board of Family Medicine Sep 2023, jabfm.2022.220391R2; DOI: 10.3122/jabfm.2022.220391R2
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