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Research ArticleOriginal Research

Perceptions and Preferences for Defining Biosimilar Products in Prescription Drug Promotion

Mihaela Johnson, Jessica E. Thompson, Avery A. Tilley, Amie C. O’Donoghue and Kathryn J. Aikin
The Journal of the American Board of Family Medicine January 2025, 38 (1) 94-106; DOI: https://doi.org/10.3122/jabfm.2024.240151R1
Mihaela Johnson
From the RTI International, Research Triangle Park, NC (MJ, JET, AAT); U.S. Food and Drug Administration, Office of Prescription Drug Promotion, Silver Spring, MD (KJA, ACO).
PhD
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Jessica E. Thompson
From the RTI International, Research Triangle Park, NC (MJ, JET, AAT); U.S. Food and Drug Administration, Office of Prescription Drug Promotion, Silver Spring, MD (KJA, ACO).
PhD
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Avery A. Tilley
From the RTI International, Research Triangle Park, NC (MJ, JET, AAT); U.S. Food and Drug Administration, Office of Prescription Drug Promotion, Silver Spring, MD (KJA, ACO).
MS
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Amie C. O’Donoghue
From the RTI International, Research Triangle Park, NC (MJ, JET, AAT); U.S. Food and Drug Administration, Office of Prescription Drug Promotion, Silver Spring, MD (KJA, ACO).
PhD
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Kathryn J. Aikin
From the RTI International, Research Triangle Park, NC (MJ, JET, AAT); U.S. Food and Drug Administration, Office of Prescription Drug Promotion, Silver Spring, MD (KJA, ACO).
PhD
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References

  1. 1.↵
    U.S. Food and Drug Administration. Biological Product Definitions. Available at: https://www.fda.gov/files/drugs/published/Biological-Product-Definitions.pdf.
  2. 2.↵
    American Cancer Society. List of Biosimilars Used in Cancer Treatment. Available at: https://www.cancer.org/cancer/managing-cancer/treatment-types/biosimilar-drugs/list.html.
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    . Biosimilars Use in Medicine for Inflammatory Diseases. 2023. National Center for Biotechnology Information. January. Available at https://www.ncbi.nlm.nih.gov/books/NBK574572/.
  4. 4.↵
    U.S. Food and Drug Administration. Biosimilars. Available at https://www.fda.gov/drugs/therapeutic-biologics-applications-bla/biosimilars.
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    Statista. Knowledge about biosimilars among consumers in the United States as of 2015. Available at: https://www.statista.com/statistics/503911/consumers-knowledge-about-biosimilars-in-the-us/.
  14. 14.↵
    U.S. Department of Health and Human Services, U.S. Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER). Promotional labeling and advertising considerations for prescription biological reference and biosimilar products questions and answers: Guidance for industry. 2020. February. Available at: https://www.fda.gov/media/134862/download.
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    1. Aikin KJ,
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    1. Betts KR,
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    3. Boudewyns V,
    4. Johnson M,
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    6. Southwell BG
    . Physician response to contextualized price-comparison claims in prescription drug advertising. J Commun Healthc 2017;10:195–204.
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  17. 17.
    1. Boudewyns V,
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    . Physician interpretation of data of uncertain clinical utility in oncology prescription drug promotion. Oncologist 2021;26:1071–8.
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    . Effect of presentation modality in direct-to-consumer (DTC) prescription drug television advertisement. Appl Ergon 2014;45:1330–6.
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  20. 20.↵
    1. Kelly BJ,
    2. Rupert DJ,
    3. Aikin KJ,
    4. et al
    . Development and validation of prescription drug risk, efficacy, and benefit perception measures in the context of direct-to-consumer prescription drug advertising. Res Social Adm Pharm 2021;17:942–55.
    OpenUrlPubMed
  21. 21.↵
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    OpenUrlPubMed
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The Journal of the American Board of Family     Medicine: 38 (1)
The Journal of the American Board of Family Medicine
Vol. 38, Issue 1
January-February 2025
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Perceptions and Preferences for Defining Biosimilar Products in Prescription Drug Promotion
Mihaela Johnson, Jessica E. Thompson, Avery A. Tilley, Amie C. O’Donoghue, Kathryn J. Aikin
The Journal of the American Board of Family Medicine Jan 2025, 38 (1) 94-106; DOI: 10.3122/jabfm.2024.240151R1

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Perceptions and Preferences for Defining Biosimilar Products in Prescription Drug Promotion
Mihaela Johnson, Jessica E. Thompson, Avery A. Tilley, Amie C. O’Donoghue, Kathryn J. Aikin
The Journal of the American Board of Family Medicine Jan 2025, 38 (1) 94-106; DOI: 10.3122/jabfm.2024.240151R1
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Keywords

  • Advertising
  • Biosimilar Pharmaceuticals
  • Comprehension
  • Direct-to-Consumer Advertising
  • Disclosure
  • Health Communication
  • Patient Education
  • Perception
  • Prescription Drugs
  • Public Health
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