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Research ArticlePRIORITY UPDATES FROM THE RESEARCH LITERATURE (PURLs)

Filtering Race Out of GFR Calculation

Winfred Frazier, Yufei Ge, Carina Brown and Greg Castelli
The Journal of the American Board of Family Medicine November 2024, 37 (6) 1146-1148; DOI: https://doi.org/10.3122/jabfm.2024.240035R0
Winfred Frazier
From the UPMC St. Margaret Family Medicine Residency Program, Pittsburgh, PA (WF, YG).
MD, MPH
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Yufei Ge
From the UPMC St. Margaret Family Medicine Residency Program, Pittsburgh, PA (WF, YG).
MD, MS
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Carina Brown
MD
Roles: FPIN Editor:
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Greg Castelli
PharmD
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  • Article
  • Figures & Data
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References

  1. 1.↵
    1. Gutiérrez OM,
    2. Sang Y,
    3. Grams ME
    , Chronic Kidney Disease Prognosis Consortiumet al. Association of estimated GFR calculated using race-free equations with kidney failure and mortality by Black vs non-Black race. JAMA 2022;327:2306–16.
    OpenUrlPubMed
  2. 2.↵
    1. Levey AS,
    2. Stevens LA,
    3. Schmid CH
    , CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009;150:604–12.
    OpenUrlCrossRefPubMedWeb of Science
  3. 3.↵
    1. Ahmed S,
    2. Nutt CT,
    3. Eneanya ND,
    4. et al
    . Examining the potential impact of race multiplier utilization in estimated glomerular filtration rate calculation on African American care outcomes. J Gen Intern Med 2020;36:464–71.
    OpenUrlPubMed
  4. 4.↵
    USRDS. United States Renal Data System. 2015 USRDS annual data report: Epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; Bethesda, MD: 2015. 2015.
  5. 5.↵
    1. Sood A,
    2. Abdullah NM,
    3. Abdollah F,
    4. et al
    . Rates of kidney transplantation from living and deceased donors for Blacks and Whites in the United States, 1998 to 2011. JAMA Intern Med 2015;175:1716–8.
    OpenUrlPubMed
  6. 6.↵
    1. Purnell TS,
    2. Luo X,
    3. Cooper LA,
    4. et al
    . Association of race and ethnicity with live donor kidney transplantation in the United States From 1995 to 2014. JAMA 2018;319:49–61.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Levey AS,
    2. Greene T,
    3. Beck GJ,
    4. et al
    . Dietary protein restriction and the progression of chronic renal disease: what have all of the results of the MDRD study shown? Modification of Diet in Renal Disease Study group. J Am Soc Nephrol 1999;10:2426–39.
    OpenUrlAbstract/FREE Full Text
  8. 8.↵
    1. Jain A,
    2. Brooks JR,
    3. Alford CC,
    4. et al
    . Awareness of racial and ethnic bias and potential solutions to address bias with use of health care algorithms. JAMA Health Forum 2023;4:e231197.
    OpenUrl
  9. 9.↵
    1. Shlipak MG,
    2. Matsushita K,
    3. Ärnlöv J
    , CKD Prognosis Consortiumet al. Cystatin C versus creatinine in determining risk based on kidney function. N Engl J Med 2013;369:932–43.
    OpenUrlCrossRefPubMedWeb of Science
  10. 10.↵
    1. Peralta CA,
    2. Shlipak MG,
    3. Judd S,
    4. et al
    . Detection of chronic kidney disease with creatinine, cystatin C, and urine albumin-to-creatinine ratio and association with progression to end-stage renal disease and mortality. JAMA 2011;305:1545–52.
    OpenUrlCrossRefPubMedWeb of Science
  11. 11.↵
    National Kidney Foundation, American Society of Nephrology. Removing race from estimates of kidney function. March 9, 2021 (https://www.asn-online.org/about/press/releases/ASN_PR_20210309_Press_release_NKF_A.pdf. opens in new tab).
  12. 12.↵
    1. Smith P,
    2. Castelli G
    . The Priority Updates from the Research Literature (PURLs) Methodology. J Am Board Fam Med 2024;37:799–802.
    OpenUrlFREE Full Text
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The Journal of the American Board of Family     Medicine: 37 (6)
The Journal of the American Board of Family Medicine
Vol. 37, Issue 6
November-December 2024
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Filtering Race Out of GFR Calculation
Winfred Frazier, Yufei Ge
The Journal of the American Board of Family Medicine Nov 2024, 37 (6) 1146-1148; DOI: 10.3122/jabfm.2024.240035R0

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Filtering Race Out of GFR Calculation
Winfred Frazier, Yufei Ge
The Journal of the American Board of Family Medicine Nov 2024, 37 (6) 1146-1148; DOI: 10.3122/jabfm.2024.240035R0
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Keywords

  • Chronic Kidney Disease
  • Cystatin C
  • End-Stage Renal Disease
  • Glomerular Filtration Rate
  • Serum Creatinine

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