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Brief ReportBrief Report

Opioid Education and Prescribing Practices

Simani M. Price, Amie C. O'Donoghue, Lou Rizzo, Saloni Sapru and Kathryn J. Aikin
The Journal of the American Board of Family Medicine July 2021, 34 (4) 802-807; DOI: https://doi.org/10.3122/jabfm.2021.04.200610
Simani M. Price
From Westat, Inc. Rockville, MD (SMP, LR, SS); U.S. Food and Drug Administration, Silver Spring, MD (ACO, KJA).
PhD
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Amie C. O'Donoghue
From Westat, Inc. Rockville, MD (SMP, LR, SS); U.S. Food and Drug Administration, Silver Spring, MD (ACO, KJA).
PhD
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Lou Rizzo
From Westat, Inc. Rockville, MD (SMP, LR, SS); U.S. Food and Drug Administration, Silver Spring, MD (ACO, KJA).
PhD
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Saloni Sapru
From Westat, Inc. Rockville, MD (SMP, LR, SS); U.S. Food and Drug Administration, Silver Spring, MD (ACO, KJA).
PhD
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Kathryn J. Aikin
From Westat, Inc. Rockville, MD (SMP, LR, SS); U.S. Food and Drug Administration, Silver Spring, MD (ACO, KJA).
PhD
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Article Figures & Data

Tables

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    Table 1.

    Characteristics of Survey Respondents

    Unweighted (N = 2,000)Weighted (N = 348,269)
    Type of Health Care Provider Group
    PCPsSPsPAsNPsPCPsSPsPAsNPs
    Total n by group700600350350104,576107,40859,53976,746
    %%%%%%%%
    Sex
        Male606625866702810
        Female4034759234307290
    Race/Hispanic identity*
        Hispanic85637664
        White6566828166708280
        Black22363226
        Asian202355201866
        Other55354435
    Age, years
        Less than 3513113318424223
        35–442930353021192826
        45–542626172131311621
        55–642123122330281022
        65 or older101238152048
    Type of practice
        Private solo or group practice6078625072826152
        Freestanding clinic/urgent care center961313751312
        Non-federal government clinic54474247
        Federal government clinics32542254
        Health maintenance organizations63363246
        Community health centers9371354713
        Other75686368
    Number of years in practice
        Less than 515122926753327
        5–102122272813132729
        11–151313151413111313
        16–201413131115181210
        More than 203739162253531621
    Number of prescriptions in a typical week
        Less than 35 prescriptions1333242916332529
        35–65 prescriptions2129293020252829
        66–125 prescriptions2722262226242822
        More than 125 prescriptions3915211938181920
    Number of patients in a typical week
        Less than 40 visits98111613111117
        40–79 visits3336425134364150
        80–119 visits4031352335283523
        120 or more visits1826131018261411
    • NPs, nurse practitioners; PAs, physician assistants; PCPs, primary care physicians; SPs, specialists.

    • ↵* Asian, Black, Other, and White race categories are Non-Hispanic.

    • View popup
    Table 2.

    Patients Prescribed Opioids and Exposure to Opioid Educational Information by Health Care Provider Group

    Type of Health Care Provider Group
    PCPsSPsPAsNPs
    Patients prescribed opioids for chronic pain during past 3 months (%)*,†
        None24.569.450.052.6
        1–5 patients25.516.424.426.0
        6–10 patients19.05.58.55.6
        11–20 patients13.73.06.26.4
        21 or more patients15.64.39.08.2
        Don't know/not sure1.61.41.81.2
    Patients prescribed opioids past 3 months versus 12 months (%)*,†
        Less43.824.526.126.5
        Same54.274.570.870.6
        More2.11.03.22.9
    Sources for opioid educational information (%)*
        Hospital or conference presentations‡41.7a33.8c27.0d40.9b
        Online presentations or webinars‖42.5b33.2d39.3d51.8a
        Sponsored event7.35.05.47.6
        Medical journals¶59.9a40.9b53.4a58.8a
        Prescribing information/REMS materials¶24.5a15.2b18.825.1a
        Promotional materials¶8.95.4b8.811.6a
        Other information sources6.52.65.55.5
    Exposure to opioid educational information during the past 12 months#
        Mean**1.91a1.36c1.58b2.01a
        95% CI1.80–2.021.04–1.491.45–1.721.88–2.16
        %exposed **89.8a71.9c78.8b85.5a
    Recall of opioid promotions††
        Mean**1.64b1.16c1.63b1.82a
        95% CI1.53–1.751.04−1.281.51–1.751.71–1.93
    ADF knowledge score‡‡
        Mean**1.91a1.23c1.49b1.48b
        95% CI1.78–2.041.09–1.371.34–1.641.34–1.63
    • ADF, abuse-deterrent formulations; BH, Benjamini-Hochberg procedure; CI, confidence interval; NPs, nurse practitioners; PAs, physician assistants; PCPs, primary care physicians; REMS, Risk Evaluation and Mitigation Strategy; SPs, specialists.

    • ↵* χ2 tests using the Agresti logit uniform association model were first conducted across the 4 groups, followed by pairwise comparisons using the BH procedure.

    • ↵† PCPs were significantly different from NPs, PAs, and SPs, BH P < .01.

    • ↵‡ a > c > d and b > d, BH adjusted, P < .05.

    • ↵‖ a > b > d and a > c, BH adjusted, P < .05.

    • ↵¶ a > b, BH adjusted P < .05.

    • ↵# A global measure of exposure to opioid educational information was created by summing the “yes” responses for each source of opioid educational information. Means represent the average exposure per group. “% exposed” represents the percentage of respondents in each health care provider group that read at least 1 opioid educational material or attended 1 opioid educational event.

    • ↵** a > b > c, BH adjusted, P < .05.

    • ↵†† “Yes” responses to questions about seeing prescription drug promotions in the last 6 months related non-opioid analgesics, medication-assisted treatment for opioid deterrence, and opioid reversal agents were combined to create an overall recall measure of prescription drug promotions.

    • ↵‡‡ Correct responses to 5 ADF questions were summed to create a total ADF knowledge score.

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    Table 3.

    Logistic Regression Model for Likelihood of Prescribing Opioids for Chronic Pain to Fewer Patients at 3 Months Relative to 12 Months Ago*

    PredictorsAdjusted Odds Ratio (95% CI)P value
    Number of patients prescribed opioids for chronic pain in last 3 months1.36 (1.23–1.49).001
    ADF knowledge score†0.99 (0.90–1.09).812
    Exposure to opioid educationalinformation in last 12 months‡1.19 (1.06–1.32).002
    Recall of opioid promotion‖1.08 (0.90–1.22).240
    Health care providers
        SPs0.61 (0.43–0.87).006
        PAs0.69 (0.48–1.01).056
        NPs0.68 (0.47–0.99).042
        PCPsReference
    Race/ethnicity¶Hispanic1.27 (0.72–2.23).407
        Asian1.27 (0.86–1.88).228
        Black1.08 (0.46–2.53).861
        Other1.12 (0.60–2.08).726
        WhiteReference
    Practice type
        Clinics/urgent care centers0.84 (0.55–1.29).433
        Non-federal government clinics1.97 (1.12–3.49).021
        Federal government clinics0.67 (0.34–1.31).237
        Health maintenance organizations0.82 (0.45–1.49).512
        Community health centers0.87 (0.56–1.35).533
        Other0.70 (0.43–1.15).158
        Solo/group practiceReference
    Sex
        Male1.23 (0.93–1.63).140
        FemaleReference
    Age1.01 (0.99–1.02).062
    • ADF, abuse-deterrent formulations; CI, confidence interval; NPs, nurse practitioners; PAs, physician assistants; PCPs, primary care physicians; SPs, specialists.

    • ↵* The outcome variable is based on responses to the question: Is the number of patients you prescribed opioids for chronic pain in the past 3 months relative to 12 months ago, the same, less, or more. Response options same and more were combined and compared to less.

    • ↵† Correct responses to 5 ADF questions were summed to create a ADF knowledge score.

    • ↵‡ Exposure to opioid educational information was created by summing “yes” responses for each source of opioid educational information.

    • ↵‖ “Yes” responses to questions about seeing prescription drug promotions in the last 6 months related non-opioid analgesics, medication-assisted treatment for opioid deterrence, and opioid reversal agents were combined to create an overall recall measure of prescription drug promotions.

    • ↵¶ Asian, Black, Other, and White race categories are Non-Hispanic.

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The Journal of the American Board of Family     Medicine: 34 (4)
The Journal of the American Board of Family Medicine
Vol. 34, Issue 4
July/August 2021
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Opioid Education and Prescribing Practices
Simani M. Price, Amie C. O'Donoghue, Lou Rizzo, Saloni Sapru, Kathryn J. Aikin
The Journal of the American Board of Family Medicine Jul 2021, 34 (4) 802-807; DOI: 10.3122/jabfm.2021.04.200610

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Opioid Education and Prescribing Practices
Simani M. Price, Amie C. O'Donoghue, Lou Rizzo, Saloni Sapru, Kathryn J. Aikin
The Journal of the American Board of Family Medicine Jul 2021, 34 (4) 802-807; DOI: 10.3122/jabfm.2021.04.200610
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