Article Figures & Data
Tables
n % Gender Female 439 64.3 Male 244 35.7 Age, years 55 to 64 106 15.5 65 to 74 337 49.3 ≥ 75 240 35.1 Education No high school diploma 168 24.6 High school diploma 242 35.4 Some college or college degree 273 40.0 Living alone No 276 40.4 Yes 407 59.6 Smoking behaviors Current smoker 142 20.8 Past smoker 214 31.4 Never smoked 326 47.8 Mean ± SD Age (years: 55 to 96) 71.8 ± 8.3 Education attainment (1 to 16) 12.8 ± 2.2 Financial strains (1 to 5) 1.8 ± 1.1 Continuity of care (0 to 3) 2.5 ± 0.66 Major chronic conditions (1 to 6) 1.8 ± 0.9 n % Valid % Low-dose aspirin use No 429 62.8 62.8 Yes 254 37.2 37.2 Prescribed versus self-prescribed aspirin use OTC 152 22.3 59.8 Rx 102 14.9 40.2 No low-dose aspirin used 429 62.8 Top 5 potentially major aspirin-drug interactions Hydrochlorothiazide 83 33.7 Metformin 58 22.8 Furosemide 49 15.7 Glipizide 32 12.6 Hydrochlorothiazide + triamterene 25 9.8 Potential major aspirin-drug interactions (among non-aspirin users) No interaction 146 34.1 34.1 One major interaction 161 37.6 37.6 Two major interactions 81 18.9 18.9 Three or more major interactions 40 9.3 9.3 Mean ± SD Frequency of potentially major aspirin-drug interaction for aspirin users 1.3 ± 1.08 Frequency of potentially major aspirin-drug interactions for non-aspirin users 1.1 ± 1.06 OTC, over-the counter.
Aspirin Used P Clinician Prescribed Self Prescribed P No, n (%) Yes, n% n (%) n (%) Gender Male 165 (68) 79 (32) .052 34 (43) 45 (57) .507 Female 264 (60) 175 (40) 68 (39) 108 (61) Age, years .03 .0001 55 to 64 (young-old) 78 (74) 28 (26) 24 (86) 4 (14) 65 to 74 (mid-old) 210 (62) 127 (38) 50 (39) 77 (61) ≥ 75 (old-old) 141 (59) 99 (41) 28 (28) 71 (72) Living alone No 177 (64) 99 (36) .557 33 (33) 66 (67) .083 Yes 252 (62) 155 (38) 69 (44) 87 (56) Education No high school diploma 105 (63) 63 (37) .946 33 (52) 30 (48) .054 High school diploma 154 (64) 88 (36) 34 (39) 54 (61) Some college 170 (62) 103 (33) 35 (34) 69 (66) Smoking .012 .003 Current smoker 102 (72) 40 (28) 22 (55) 18 (45) Past smoker 138 (65) 76 (36) 38 (49) 39 (51) Never smoked 188 (58) 138 (42) 42 (30) 96 (70) GI conditions No 302 (64) 171 (36) .487 63 (37) 109 (63) .081 Yes 127 (61) 81 (39) 39 (48) 42 (52) Diabetes mellitus .005 .664 No 296 (67) 147 (33) 58 (39) 90 (61) Yes 133 (56) 105 (44) 44 (42) 61 (58) Heart conditions .0001 .544 No 329 (68) 153 (32) 64 (42) 89 (58) Yes 100 (50) 99 (50) 38 (38) 62 (62) Stroke .808 .011 No 370 (63) 219 (37) 82 (37) 138 (63) Yes 59 (64) 33 (36) 20 (61) 13 (39) Mean (SD) Mean (SD) Age (years: 55 to 96) 71.2 (8.3) 72.7 (8.1) .019 69.5 (7.7) 74.8 (7.7) .0001 Education attainment (1 to 16) 12.8 (2.0) 12.7 (2.5) .368 12.4 (2.5) 12.9 (2.5) .126 Financial strains (1 to 5) 1.8 (1.1) 1.7 (1.0) .066 2.0 (1.2) 1.5 (.8) .0001 Continuity of care (0 to 3) 2.5 (0.6) 2.5 (0.6) .789 2.4 (0.7) 2.6 (.6) .007 Major chronic conditions (1 to 6) 1.7 (1.0) 2.0 (0.9) .0001 2.1 (0.9) 1.9 (.9) .273 GI, gastrointestinal; SD, standard deviation.
- Table 4.
Binary Logistic Regression between Independent Variables and Low-Dose Aspirin Used (n = 683)
Independent Variables Low-Aspirin Used Vs No Used Sig. OR 95% CI Gender 0.93-1.89 0.121 Male 1.32 Female 1 Age, years 55 to 64 (young–old) 0.73 0.41-1.33 0.306 65 to 74 (mid-old) 0.99 0.69-1.43 0.972 ≥ 75 (old-old) 1 Living alone No 1.12 0.85-1.68 0.296 Yes 1 Education No high school diploma 1.02 0.66-1.55 0.956 High school diploma 0.96 0.66-1.39 0.946 Some college 1 0.815 Smoking Current smoker 0.69 0.42-1.12 0.266 Past smoker 0.79 0.53-1.17 0.137 Never smoked 1 0.24 Continuity of Care (scale: 0 – 3) 0.86 0.66-1.11 0.239 Financial Stress (scale: 1 to 5) 0.947 0.80-1.13 0.063 Heart conditions No 2.24 1.55-3.23 0.001 Yes 1 Diabetes Mellitus No 1.51 1.07-2.14 0.019 Yes 1 Stroke No 0.85 0.53-1.40 0.553 Yes 1 GI conditions No 0.91 0.62-133 0.616 Yes 1 Potentially major aspirin-drug interaction No 0.79 0.70-1.41 0.959 Yes 1 GI, gastrointestinal; OR, odds ratio; CI, confidence interval; Sig, Sigma.
Note: −2 Log Likelihood: 857; Sig: 0.0001; Nagelkerke: 0.080.
- Table 5.
Multinomial Logistic Regression between Independent Variables and Low-Dose Aspirin Used (Self-Prescribed, Clinician-Prescribed Versus No Use (n = 683)
Independent Variables Clinician Prescribed Sig. Self Prescribed Sig. OR 95% CI OR 95% CI Gender 0.80-2.12 0.298 0.197 Male 1.3 1.34 0.86-2.07 Female 1 1 Age, years 55 to 64 (young–old) 1.88 0.91-3.91 0.89 0.17 0.06-0.52 0.002 65 to 74 (mid-old) 1.47 0.85-2.52 0.175 0.81 0.53-1.24 0.332 ≥ 75 (old-old) 1 1 Living alone No 1.57 0.97-2.54 0.068 1.02 0.68-1.54 0.91 Yes 1 1 Education No high school diploma 1.58 0.90-2.76 0.122 0.71 0.41-1.21 0.208 High school diploma 1.05 0.61-1.80 0.858 0.89 0.57-1.39 0.606 Some college 1 1 Smoking Current smoker 0.82 0.42-1.57 0.541 0.64 0.34-1.21 0.17 Past smoker 0.97 0.57-1.66 0.908 0.73 0.45-1.17 0.189 Never smoked 1 1 Continuity of care (scale: 0 – 3) 0.72 0.51-1.02 0.298 0.97 0.70-1.35 0.864 Financial Stress (scale: 1 to 5) 1.04 0.842-1.30 0.063 0.85 0.67-1.09 0.179 Heart conditions No 2.05 1.23-3.41 0.006 2.41 1.56-3.73 0.001 Yes 1 1 Diabetes mellitus No 1.72 1.07-2.76 0.027 1.39 0.92-2.11 0.122 Yes 1 1 Stroke No 1.4 0.77-2.53 0.269 0.55 0.28-1.06 0.075 Yes 1 1 GI conditions No 0.98 0.58– 1.63 0.925 0.85 0.53-1.36 0.497 Yes 1 1 Potentially major aspirin-drug interaction No 1.26 0.76-2.10 0.371 1.2 0.79-1.82 0.401 Yes 1 OR, odds ratio; CI, confidence interval; Sig, Sigma; GI, gastrointestinal.
The reference category is: No low-dose aspirin used; −2 Log Likelihood: 1084; df = 30, χ2 = 09.41, Sig: 0.0001; Nagelkerke: 0.151.
