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Review ArticleClinical Review

Cervical Spondylotic Myelopathy: A Guide to Diagnosis and Management

Johnathon R. McCormick, Andrew J. Sama, Nicholas C. Schiller, Alexander J. Butler and Chester J. Donnally
The Journal of the American Board of Family Medicine March 2020, 33 (2) 303-313; DOI: https://doi.org/10.3122/jabfm.2020.02.190195
Johnathon R. McCormick
From the University of Miami Leonard M. Miller School of Medicine, Department of Education, Miami, FL (JRM, AJS, NCS); University of Miami Hospital, Department of Orthopaedic Surgery, Miami, FL (AJB); The Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA (CJD).
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Andrew J. Sama
From the University of Miami Leonard M. Miller School of Medicine, Department of Education, Miami, FL (JRM, AJS, NCS); University of Miami Hospital, Department of Orthopaedic Surgery, Miami, FL (AJB); The Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA (CJD).
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Nicholas C. Schiller
From the University of Miami Leonard M. Miller School of Medicine, Department of Education, Miami, FL (JRM, AJS, NCS); University of Miami Hospital, Department of Orthopaedic Surgery, Miami, FL (AJB); The Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA (CJD).
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Alexander J. Butler
From the University of Miami Leonard M. Miller School of Medicine, Department of Education, Miami, FL (JRM, AJS, NCS); University of Miami Hospital, Department of Orthopaedic Surgery, Miami, FL (AJB); The Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA (CJD).
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Chester J. Donnally III
From the University of Miami Leonard M. Miller School of Medicine, Department of Education, Miami, FL (JRM, AJS, NCS); University of Miami Hospital, Department of Orthopaedic Surgery, Miami, FL (AJB); The Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA (CJD).
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Article Figures & Data

Figures

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  • Figure 1.
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    Figure 1.

    Select physical examination maneuvers to support a diagnosis of cervical spondylotic myelopathy. (A) Finger escape sign; (B) grip and release test; (C) hyperactive pectoralis reflex; (D) inverted radial reflex; (E) Hoffman sign.

  • Figure 2.
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    Figure 2.

    Lateral cervical spine radiograph demonstrating Torg-Pavlov ratio at C5. Calculated by dividing canal diameter (A) by vertebral body diameter (B). Ratio <0.8 signifies canal stenosis. Canal diameter <12 mm is correlated with cord compression.

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    Figure 3.

    Algorithm to aid in the diagnosis, work-up, management, and appropriate referral of a patient with suspected cervical spondylotic myelopathy. Abbreviations: CSM, Client Services Manager; CT, computed tomography; MRI, Magnetic Resonance Imaging; JOA, Japanese Orthopaedic Association.

Tables

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    Table 1.

    Nurick Scale for Clinical Myelopathy Evaluation (0 to 5 Points)

    GradeDescription
    0Signs and symptoms of root involvement without spinal cord disease
    1Signs of spinal cord disease without difficulty in walking
    2Slight difficulty in walking that does not prevent full-time employment
    3Difficulty in walking that prevents full-time employment or daily takes without requiring assistance with walking
    4Ability to walk only with assistance
    5Chair bound or bedridden
    • View popup
    Table 2.

    Symptoms and Physical Exam Findings Commonly Seen in Patients with Cervical Spondylotic Myelopathy

    Upper Extremity FindingsLower Extremity FindingsAdditional Findings
    *Decreased hand dexterity*Impairment of gait and/or fallsLhermitte’s phenomenon
    Lower motor neuron signs (muscle weakness, atrophy, fasciculation, hyporeflexia, hypotonia)Upper motor neuron signs (weakness, hyperreflexia, hypertonia)Incontinence
    Change in pain, temperature, proprioception, dermatomal sensationChange in pain, temperature, proprioception, dermatomal sensationNeck pain
    Motor deficitsMotor deficits
    Thenar atrophyBabinski reflex
    Hoffman signRomberg test
    Inverted radial reflexSustained foot clonus
    Finger escape sign
    Grip and release test
    Hyperactive pectoralis reflex
    • ↵* Most frequently found upon initial presentation.

    • View popup
    Table 3.

    Japanese Orthopaedic Association Scale for Cervical Myelopathy Evaluation (0 to 17 Points)

    Evaluation DescriptionPoint
    Motor function of upper limbs
     Unable to eat with cutlery or to button shirt0
     Unable to eat with a spoon, but able to move hands1
     Able to button shirt with great difficulty2
     Able to button shirt with slight difficulty3
     No dysfunction4
    Motor dysfunction score of the lower extremity
     Complete loss of motor and sensory function0
     Sensory preservation without ability to move legs1
     Able to move legs, but unable to walk2
     Able to walk on flat floor with a walking aid3
     Able to walk up and/or down stairs with hand rail4
     Moderate-to-significant lack of stability, but able to walk up and/or down without hand rail5
     Mild lack of stability but walks with smooth reciprocation unaided6
     No dysfunction7
    Sensory dysfunction score of the upper extremities
     Complete loss of motor and sensory function0
     Severe sensory loss of pain1
     Mild sensory loss2
     No sensory loss3
    Sphincter dysfunction score
     Unable to micturate voluntarily0
     Marked difficulty with micturition1
     Mild to moderate difficulty with micturition2
     Normal micturition3
    • View popup
    Table 4.

    Imaging Modalities Used in the Workup of Cervical Spondylotic Myelopathy with Their Respective Utility and Associated Cost

    Imaging ModalityUtility†Cost
    *Magnetic resonance imagingVisualize intervertebral discs, ligaments, and surrounding soft tissues; obtain transverse area of spinal cord; determine severity of cord compression and degeneration; diagnose CCSSMean operating expense: $165
    Mean charge per procedure: $2048
    RadiographsDetermine lordosis/kyphosis; calculate Torg-Pavlov ratio; evaluate spinal column alignment, ROM, and flexion/extensionMean operating expense: $55
    Mean charge per procedure: $410
    Computed tomography (± myelography)Diagnose OPLL; assess transverse foramen for vertebral artery compression; evaluate cervical cord compression; obtain transverse area of spinal cord; perform CT-myelogram in patients with contraindication to MRIMean operating expense: $51
    Mean charge per procedure: $1565
    ElectrophysiologyAssess peripheral neurologic functionality; rule out other neurologic diseasesMean operating expense: varies
    Mean charge per procedure: varies
    • CCSS, congenital cervical spinal stenosis; ROM, range of motion; OPLL, ossification of the posterior longitudinal ligament.

    • ↵* Preferred modality.

    • ↵†Data from reference 41.

    • View popup
    Table 5.

    AOSpine North America and Cervical Spine Research Society Guidelines for Management of Cervical Spondylotic Myelopathy Based on Japanese Orthopaedic Association Severity

    ClassificationJOA ScoreRecommendationStrength of RecommendationQuality of Evidence
    Mild CSM15 to 17Offer surgery or trial of structured rehabilitationWeakVery low to low
    Moderate CSM12 to 14Surgical interventionStrongModerate
    Severe CSM0 to 11Surgical interventionStrongModerate
    • CSM, cervical spondylotic myelopathy; JOA, Japanese Orthopaedic Association.

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The Journal of the American Board of Family  Medicine: 33 (2)
The Journal of the American Board of Family Medicine
Vol. 33, Issue 2
March/April 2020
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Cervical Spondylotic Myelopathy: A Guide to Diagnosis and Management
Johnathon R. McCormick, Andrew J. Sama, Nicholas C. Schiller, Alexander J. Butler, Chester J. Donnally
The Journal of the American Board of Family Medicine Mar 2020, 33 (2) 303-313; DOI: 10.3122/jabfm.2020.02.190195

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Cervical Spondylotic Myelopathy: A Guide to Diagnosis and Management
Johnathon R. McCormick, Andrew J. Sama, Nicholas C. Schiller, Alexander J. Butler, Chester J. Donnally
The Journal of the American Board of Family Medicine Mar 2020, 33 (2) 303-313; DOI: 10.3122/jabfm.2020.02.190195
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