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Review ArticleClinical Review

Hyperlipidemia: Management with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors

Muhammed Shahreyar, Salem A. Salem, Mannu Nayyar, Lekha K. George, Nadish Garg and Santhosh K.G. Koshy
The Journal of the American Board of Family Medicine July 2018, 31 (4) 628-634; DOI: https://doi.org/10.3122/jabfm.2018.04.170447
Muhammed Shahreyar
From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
MD
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Salem A. Salem
From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
MD
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Mannu Nayyar
From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
MD
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Lekha K. George
From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
MD
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Nadish Garg
From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
MD
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Santhosh K.G. Koshy
From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
MD, MBA
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Article Information

vol. 31 no. 4 628-634
DOI 
https://doi.org/10.3122/jabfm.2018.04.170447
PubMed 
29986989

Published By 
The Journal of the American Board of Family Medicine
Print ISSN 
1557-2625
Online ISSN 
1558-7118
History 
  • Received for publication November 24, 2017
  • Revision received January 17, 2018
  • Accepted for publication January 21, 2018
  • Published online July 9, 2018.

Copyright & Usage 
© Copyright 2018 by the American Board of Family Medicine.

Author Information

  1. Muhammed Shahreyar, MD,
  2. Salem A. Salem, MD,
  3. Mannu Nayyar, MD,
  4. Lekha K. George, MD,
  5. Nadish Garg, MD and
  6. Santhosh K.G. Koshy, MD, MBA
  1. From Division of Cardiology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis, TN (MS, SAS, MN, NG, SKGK); Division of Nephrology, Department of Medicine, University of Tennessee Health Sciences Center, Memphis (LKG); Department of Physician Assistant Studies, University of Tennessee Health Sciences Center, Memphis (LKG); Regional One Health, Memphis (SKGK).
  1. Corresponding author: Santhosh K.G. Koshy, MD, MBA, Professor of Medicine and Vice Chairman, Department of Medicine, University of Tennessee Health Sciences Center, 956 Court Avenue, Suite A312, Memphis, TN 38163 (E-mail: skoshy{at}uthsc.edu).
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The Journal of the American Board of Family     Medicine: 31 (4)
The Journal of the American Board of Family Medicine
Vol. 31, Issue 4
July-August 2018
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Hyperlipidemia: Management with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors
Muhammed Shahreyar, Salem A. Salem, Mannu Nayyar, Lekha K. George, Nadish Garg, Santhosh K.G. Koshy
The Journal of the American Board of Family Medicine Jul 2018, 31 (4) 628-634; DOI: 10.3122/jabfm.2018.04.170447

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Hyperlipidemia: Management with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors
Muhammed Shahreyar, Salem A. Salem, Mannu Nayyar, Lekha K. George, Nadish Garg, Santhosh K.G. Koshy
The Journal of the American Board of Family Medicine Jul 2018, 31 (4) 628-634; DOI: 10.3122/jabfm.2018.04.170447
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  • Article
    • Abstract
    • Role of PCSK9 in Cholesterol Metabolism
    • PCSK9 Inhibitors
    • Efficacy of Monoclonal Antibodies to PCSK9 and Their Impact on Cardiovascular Outcomes
    • Safety Profile of the Monoclonal Antibodies to PCSK9
    • Clinical Implications
    • Summary
    • Notes
    • References
  • Figures & Data
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