Skip to main content

Main menu

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • Other Publications
    • abfm

User menu

Search

  • Advanced search
American Board of Family Medicine
  • Other Publications
    • abfm
American Board of Family Medicine

American Board of Family Medicine

Advanced Search

  • HOME
  • ARTICLES
    • Current Issue
    • Ahead of Print
    • Archives
    • Abstracts In Press
    • Special Issue Archive
    • Subject Collections
  • INFO FOR
    • Authors
    • Reviewers
    • Call For Papers
    • Subscribers
    • Advertisers
  • SUBMIT
    • Manuscript
    • Peer Review
  • ABOUT
    • The JABFM
    • The Editing Fellowship
    • Editorial Board
    • Indexing
    • Editors' Blog
  • CLASSIFIEDS
  • JABFM on Bluesky
  • JABFM On Facebook
  • JABFM On Twitter
  • JABFM On YouTube
Brief ReportBrief Report

Low-Dose Quetiapine Induced or Worsened Mania in the Context of Possible Undertreatment

Hun Y. Millard, Barbara A. Wilson and Douglas L. Noordsy
The Journal of the American Board of Family Medicine January 2015, 28 (1) 154-158; DOI: https://doi.org/10.3122/jabfm.2015.01.140105
Hun Y. Millard
From the Department of Psychiatry, Geisel School of Medicine, Dartmouth University, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
MD, MA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Barbara A. Wilson
From the Department of Psychiatry, Geisel School of Medicine, Dartmouth University, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Douglas L. Noordsy
From the Department of Psychiatry, Geisel School of Medicine, Dartmouth University, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. 1.↵
    1. Vieta E
    . Mood stabilization in the treatment of bipolar disorder: focus on quetiapine. Hum Psychopharmacol 2005;20:225–36.
    OpenUrlPubMed
  2. 2.↵
    1. Vieta E,
    2. Calabrese JR,
    3. Goikolea JM,
    4. Raines S,
    5. Macfadden W
    ; BOLDER Study Group. Quetiapine monotherapy in the treatment of patients with bipolar I or II depression and a rapid-cycling disease course: a randomized, double-blind, placebo-controlled study. Bipolar Disord 2007;9:413–25.
    OpenUrlCrossRef
  3. 3.↵
    1. Calabrese JR,
    2. Elhaj O,
    3. Gajwani P,
    4. Gao K
    . Clinical highlights in bipolar depression: focus on atypical antipsychotics. J Clin Psychiatry 2005;66(Suppl 5):26–33.
    OpenUrl
  4. 4.↵
    1. Biancosino B,
    2. Marmai L,
    3. Facchi A,
    4. Rossi E,
    5. Grassi L
    . Quetiapine may induce mania: a case report. Can J Psychiatry 2003;48:349–50.
    OpenUrlCrossRefPubMed
  5. 5.↵
    1. Erberk-Ozen N
    . Manic symptoms probably associated with short-term low-dose quetiapine use. Adv Ther 2008;25:53–8.
    OpenUrlPubMed
  6. 6.↵
    1. Benazzi F
    . Quetiapine-associated hypomania in a woman with schizoaffective disorder. Can J Psychiatry 2001;46:182–3.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Cordoba S,
    2. de Asis J,
    3. Kotbi N,
    4. Mahgoub N
    . Worsening mania associated with slow increase of quetiapine dose. J Neuropsychiatry Clin Neurosci 2011;23:E5–6.
    OpenUrlCrossRefPubMed
  8. 8.↵
    1. Gnanavel S
    . Quetiapine-induced manic episode: a paradox for contemplation. BMJ Case Rep 2013;2013. pii:bcr2013201761.
    OpenUrlAbstract/FREE Full Text
  9. 9.↵
    1. Khalil RB,
    2. Baddoura C
    . Quetiapine induced hypomania: a case report and a review of the literature. Curr Drug Saf 2012;7:250–3.
    OpenUrlPubMed
  10. 10.↵
    1. Lykouras L,
    2. Oulis P,
    3. Hatzimanolis J
    . Manic symptoms associated with quetiapine treatment. Eur Neuropsychopharmacol 2003;13:135–6.
    OpenUrlPubMed
  11. 11.↵
    1. Mishra A,
    2. Moore PB,
    3. Hobbs R
    . Does quetiapine have mood altering properties? J Psychopharmacol 2004;18:281–4.
    OpenUrlCrossRefPubMedWeb of Science
  12. 12.↵
    1. Pacchiarotti I,
    2. Manfredi G,
    3. Kotzalidis GD,
    4. Girardi P,
    5. Tatarelli R
    . Quetiapine-induced mania. Aust N Z J Psychiatry 2003;37:626.
    OpenUrlPubMed
  13. 13.↵
    1. Atmaca M,
    2. Kuloglu M,
    3. Buyukbayram A,
    4. Tezcan E
    . Quetiapine-associated and dose-related hypomania in a woman with schizophrenia. Eur Psychiatry 2002;17:292–3.
    OpenUrlCrossRefPubMedWeb of Science
  14. 14.↵
    1. Stahl S
    . Stahl's essential psychopharmacology: neuroscientific basis and practical application. 4th ed. Cambridge: Cambridge University Press; 2013.
  15. 15.↵
    1. Rachid F,
    2. Bertschy G,
    3. Bondolfi G,
    4. Aubry JM
    . Possible induction of mania or hypomania by atypical antipsychotics: an updated review of reported cases. J Clin Psychiatry 2004;65:1537–45.
    OpenUrlCrossRefPubMedWeb of Science
  16. 16.↵
    1. Michalopoulou PG,
    2. Lykouras L
    . Manic/hypomanic symptoms induced by atypical antipsychotics: a review of the reported cases. Prog Neuropsychopharmacol Biol Psychiatry 2006;30:549–64.
    OpenUrlCrossRefPubMed
  17. 17.↵
    Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.
  18. 18.↵
    1. Stern TA,
    2. Rosenbaum JF,
    3. Fava M,
    4. Biederman J,
    5. Rauch S
    . Massachusetts General Hospital comprehensive clinical psychiatry. Philadelphia: Mosby; 2008.
  19. 19.↵
    1. Benyamina A,
    2. Samalin L
    . Atypical antipsychotic-induced mania/hypomania: a review of recent case reports and clinical studies. Int J Psychiatry Clin Pract 2012;16:2–7.
    OpenUrlCrossRefPubMed
PreviousNext
Back to top

In this issue

The Journal of the American Board of Family     Medicine: 28 (1)
The Journal of the American Board of Family Medicine
Vol. 28, Issue 1
January-February 2015
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Board of Family Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Low-Dose Quetiapine Induced or Worsened Mania in the Context of Possible Undertreatment
(Your Name) has sent you a message from American Board of Family Medicine
(Your Name) thought you would like to see the American Board of Family Medicine web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
13 + 2 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Low-Dose Quetiapine Induced or Worsened Mania in the Context of Possible Undertreatment
Hun Y. Millard, Barbara A. Wilson, Douglas L. Noordsy
The Journal of the American Board of Family Medicine Jan 2015, 28 (1) 154-158; DOI: 10.3122/jabfm.2015.01.140105

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Low-Dose Quetiapine Induced or Worsened Mania in the Context of Possible Undertreatment
Hun Y. Millard, Barbara A. Wilson, Douglas L. Noordsy
The Journal of the American Board of Family Medicine Jan 2015, 28 (1) 154-158; DOI: 10.3122/jabfm.2015.01.140105
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Case Review
    • Review of the Literature
    • Discussion
    • Conclusion
    • Acknowledgments
    • Notes
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Factors Influencing Changing Scopes of Practice Among Contemporary Graduates of the Nation’s Largest Family Medicine Residency
  • Association of Social Needs with Diabetes Outcomes in an Older Population
  • Patient Perspectives on Delayed Specialty Follow-Up After a Primary Care Visit
Show more Brief Reports

Similar Articles

Keywords

  • Bipolar Disorder
  • Mental Health
  • Pharmacotherapy
  • Psychiatry
  • Quetiapine

Navigate

  • Home
  • Current Issue
  • Past Issues

Authors & Reviewers

  • Info For Authors
  • Info For Reviewers
  • Submit A Manuscript/Review

Other Services

  • Get Email Alerts
  • Classifieds
  • Reprints and Permissions

Other Resources

  • Forms
  • Contact Us
  • ABFM News

© 2025 American Board of Family Medicine

Powered by HighWire