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Association between C-Reactive Protein Rapid Test and Group A Streptococcus Infection in Acute Pharyngitis

Olga Calviño, Carl Llor, Frederic Gómez, Eva González, Carolina Sarvisé and Silvia Hernández
The Journal of the American Board of Family Medicine May 2014, 27 (3) 424-426; DOI: https://doi.org/10.3122/jabfm.2014.03.130315
Olga Calviño
the Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff, UK (CL); Primary Care Center Jaume I, Tarragona, Spain (OC, SH); and the Department of Laboratory and Microbiology, Hospital Joan XXIII, Tarragona, Spain (FG, EG, CS).
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Carl Llor
the Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff, UK (CL); Primary Care Center Jaume I, Tarragona, Spain (OC, SH); and the Department of Laboratory and Microbiology, Hospital Joan XXIII, Tarragona, Spain (FG, EG, CS).
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Frederic Gómez
the Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff, UK (CL); Primary Care Center Jaume I, Tarragona, Spain (OC, SH); and the Department of Laboratory and Microbiology, Hospital Joan XXIII, Tarragona, Spain (FG, EG, CS).
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Eva González
the Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff, UK (CL); Primary Care Center Jaume I, Tarragona, Spain (OC, SH); and the Department of Laboratory and Microbiology, Hospital Joan XXIII, Tarragona, Spain (FG, EG, CS).
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Carolina Sarvisé
the Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff, UK (CL); Primary Care Center Jaume I, Tarragona, Spain (OC, SH); and the Department of Laboratory and Microbiology, Hospital Joan XXIII, Tarragona, Spain (FG, EG, CS).
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Silvia Hernández
the Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff, UK (CL); Primary Care Center Jaume I, Tarragona, Spain (OC, SH); and the Department of Laboratory and Microbiology, Hospital Joan XXIII, Tarragona, Spain (FG, EG, CS).
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    Figure 1.

    Association between C-reactive protein concentrations and the cause of infection among patients with sore throat and 4 Centor criteria.

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    Table 1. C-Reactive Protein (CRP) Concentrations Based on the Bacteria Causing Pharyngitis in Patients with 4 Centor Criteria
    OrganismPatients, n (%)CRP Concentrations (mg/L)
    Mean (95% CI)Median (IQR)
    GAS83 (56.1)34.4 (25.6–43.3)12.0 (4.0–62.0)
    Non-GAS infection*65 (43.9)29.9 (19.7–40.2)8.0 (4.0–46.0)
        No bacteria29 (19.6%)27.9 (11.0–44.9)4.0 (4.0–37.5)
        Group B streptococcus8 (5.4%)19.1 (0–41.0)4.0 (4.0–36.7)
        Group C streptococcus13 (8.8)56.3 (25.7–86.9)61.0 (4.0–94.5)
        Group G streptococcus5 (3.4)31.6 (0–65.3)38.0 (4.0–56.0)
        Other streptococci10 (6.7)9.2 (4.4–14.0)8.0 (4.0–11.2)
    • CI, confidence interval; GAS, group A streptococcus; IQR, interquartile range.

    • ↵* One patient had infection from a bacteria not included here.

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The Journal of the American Board of Family     Medicine: 27 (3)
The Journal of the American Board of Family Medicine
Vol. 27, Issue 3
May-June 2014
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Association between C-Reactive Protein Rapid Test and Group A Streptococcus Infection in Acute Pharyngitis
Olga Calviño, Carl Llor, Frederic Gómez, Eva González, Carolina Sarvisé, Silvia Hernández
The Journal of the American Board of Family Medicine May 2014, 27 (3) 424-426; DOI: 10.3122/jabfm.2014.03.130315

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Association between C-Reactive Protein Rapid Test and Group A Streptococcus Infection in Acute Pharyngitis
Olga Calviño, Carl Llor, Frederic Gómez, Eva González, Carolina Sarvisé, Silvia Hernández
The Journal of the American Board of Family Medicine May 2014, 27 (3) 424-426; DOI: 10.3122/jabfm.2014.03.130315
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  • Antibiotics
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