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Research ArticleOriginal Research

A Randomized Controlled Trial to Improve Colon Cancer Screening in Rural Family Medicine: An Iowa Research Network (IRENE) Study

Barcey T. Levy, Yinghui Xu, Jeanette M. Daly and John W. Ely
The Journal of the American Board of Family Medicine September 2013, 26 (5) 486-497; DOI: https://doi.org/10.3122/jabfm.2013.05.130041
Barcey T. Levy
From the Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine (BTL, YX, JMD, JWE), and the Department of Epidemiology, College of Public Health (BTL), University of Iowa, Iowa City.
PhD, MD
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Yinghui Xu
From the Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine (BTL, YX, JMD, JWE), and the Department of Epidemiology, College of Public Health (BTL), University of Iowa, Iowa City.
MS
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Jeanette M. Daly
From the Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine (BTL, YX, JMD, JWE), and the Department of Epidemiology, College of Public Health (BTL), University of Iowa, Iowa City.
PhD, RN
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John W. Ely
From the Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine (BTL, YX, JMD, JWE), and the Department of Epidemiology, College of Public Health (BTL), University of Iowa, Iowa City.
MD, MSPH
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References

  1. 1.↵
    1. Subramanian S,
    2. Bobashev G,
    3. Morris RJ
    . Modeling the cost-effectiveness of colorectal cancer screening: policy guidance based on patient preferences and compliance. Cancer Epidemiol Biomarkers Prev 2009;18:1971–8.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    1. Vogelaar I,
    2. van Ballegooijen M,
    3. Schrag D,
    4. et al
    . How much can current interventions reduce colorectal cancer mortality in the U.S.? Mortality projections for scenarios of risk-factor modification, screening, and treatment. Cancer 2006;107:1624–33.
    OpenUrlCrossRefPubMedWeb of Science
  3. 3.↵
    National Center for Chronic Disease Prevention and Health Promotion, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention (CDC). Colorectal cancer: 1 in 3 adults are not being screened. July 2011. Available from: www.cdc.gov/VitalSigns/pdf/2011-07-vitalsigns.pdf. Accessed July 13, 2011.
  4. 4.↵
    National Cancer Institute. Colorectal cancer screening (PDQ). Available from: http://www.cancer.gov/cancertopics/pdq/screening/colorectal/HealthProfessional. Accessed July 13, 2011.
  5. 5.↵
    1. Zauber AG,
    2. Winawer SJ,
    3. O'Brien MJ,
    4. et al
    . Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med 2012;366:687–96.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    1. Telford JJ,
    2. Levy AR,
    3. Sambrook JC,
    4. et al
    . The cost-effectiveness of screening for colorectal cancer. Can Med Assoc J 2010;182:1307–13.
    OpenUrlAbstract/FREE Full Text
  7. 7.↵
    U.S. Preventive Services Task Force. Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2008;149:627–37.
    OpenUrlCrossRefPubMedWeb of Science
  8. 8.↵
    1. Levin B,
    2. Lieberman DA,
    3. McFarland B,
    4. et al
    . Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology 2008;134:1570–95.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    1. Smith RA,
    2. Cokkinides V,
    3. Brooks D,
    4. Saslow D,
    5. Brawley OW
    . Cancer screening in the United States, 2010: a review of current American Cancer Society guidelines and issues in cancer screening. CA Cancer J Clin 2010;60:99–119.
    OpenUrlCrossRefPubMedWeb of Science
  10. 10.↵
    National Health Service. NHS Bowel Cancer Screening Programme. Available from: http://www. cancerscreening.nhs.uk/bowel/index.html. Accessed August 27, 2012.
  11. 11.↵
    1. Yeazel M,
    2. Church TR,
    3. Jones RM,
    4. et al
    . Colorectal cancer screening adherence in a general population. Cancer Epidemiol Biomarkers Prev 2004;13:654–7.
    OpenUrlAbstract/FREE Full Text
  12. 12.↵
    1. Levy BT,
    2. Dawson J,
    3. Hartz AJ,
    4. James PA
    . Colorectal cancer testing among patients cared for by Iowa family physicians. Am J Prev Med 2006;31:193–201.
    OpenUrlCrossRefPubMedWeb of Science
  13. 13.↵
    1. Crawford ND,
    2. Jones CP,
    3. Richardson LC
    . Understanding racial and ethnic disparities in colorectal cancer screening: Behavioral Risk Factor Surveillance System, 2002 and 2004. Ethn Dis 2010;20:359–65.
    OpenUrlPubMed
  14. 14.↵
    1. Logan RF,
    2. Patnick J,
    3. Nickerson C,
    4. et al
    . Outcomes of the Bowel Cancer Screening Programme (BCSP) in England after the first 1 million tests. Gut 2012;61:1439–46.
    OpenUrlAbstract/FREE Full Text
  15. 15.↵
    1. Stone EG,
    2. Morton SC,
    3. Hulscher ME,
    4. et al
    . Interventions that increase use of adult immunization and cancer screening services: a meta-analysis. Ann Intern Med 2002;136:641–51.
    OpenUrlCrossRefPubMedWeb of Science
  16. 16.↵
    1. Hibbard JH,
    2. Stockard J,
    3. Mahoney ER,
    4. Tusler M
    . Development of the Patient Activation Measure (PAM): conceptualizing and measuring activation in patients and consumers. Health Serv Res 2004;39:1005–26.
    OpenUrlCrossRefPubMedWeb of Science
  17. 17.↵
    1. Hollon MF
    . Direct-to-consumer advertising: a haphazard approach to health promotion. JAMA 2005;293:2030–3.
    OpenUrlCrossRefPubMedWeb of Science
  18. 18.↵
    1. Kravitz RL,
    2. Epstein RM,
    3. Feldman MD,
    4. et al
    . Influence of patients' requests for direct-to-consumer advertised antidepressants: a randomized controlled trial. JAMA 2005;293:1995–2002.
    OpenUrlCrossRefPubMedWeb of Science
  19. 19.↵
    1. Shea S,
    2. DuMouchel W,
    3. Bahamonde L
    . A meta-analysis of 16 randomized controlled trials to evaluate computer-based clinical reminder systems for preventive care in the ambulatory setting. J Am Med Inform Assoc 1996;3:399–409.
    OpenUrlAbstract/FREE Full Text
  20. 20.↵
    1. Walsh JM,
    2. McPhee SJ
    . A systems model of clinical preventive care: an analysis of factors influencing patient and physician. Health Educ Q 1992;19:157–75.
    OpenUrlPubMedWeb of Science
  21. 21.↵
    1. Wagner EH
    . Chronic disease management: what will it take to improve care for chronic illness? Eff Clin Pract 1998;1:2–4.
    OpenUrlPubMed
  22. 22.↵
    1. Daly J,
    2. Xu Y,
    3. Ely JW,
    4. Levy BT
    . A randomized colorectal screening intervention trial in the Iowa Research Network: study recruitment and baseline results. J Am Board Fam Med 2012;25:63–72.
    OpenUrlAbstract/FREE Full Text
  23. 23.↵
    1. Levy BT,
    2. Daly JM,
    3. Xu Y,
    4. Ely JW
    . Mailed fecal immunochemical tests plus education materials to improve colon cancer screening rates in Iowa Research Network (IRENE) practices. J Am Board Fam Med 2012;25:73–82.
    OpenUrlAbstract/FREE Full Text
  24. 24.↵
    1. Dillman DA
    . Mail and internet surveys: the tailored design method. 2nd ed. Hoboken, NJ: John Wiley & Sons; 2007.
  25. 25.↵
    1. Levy BT,
    2. Nordin T,
    3. Sinift S,
    4. Rosenbaum M,
    5. James PA
    . Why hasn't this patient been screened for colon cancer? An Iowa Research Network study. J Am Board Fam Med 2007;20:458–68.
    OpenUrlAbstract/FREE Full Text
  26. 26.↵
    1. Vernon SW,
    2. Meissner H,
    3. Klabunde C,
    4. et al
    . Measures for ascertaining use of colorectal cancer screening in behavioral, health services, and epidemiologic research. Cancer Epidemiol Biomarkers Prev 2004;13:898–905.
    OpenUrlFREE Full Text
  27. 27.↵
    American Cancer Society. Get Tested for colon cancer. Here's how [DVD]. Atlanta, GA: American Cancer Society; 2008.
  28. 28.↵
    American Cancer Society. They know how to prevent colon cancer–and you can too. Take a look inside. No. 243900, rev. 01/08. Available from: http://www. cancer.org/acs/groups/content/@healthpromotions/documents/document/acsq-020998.pdf. Accessed July 23, 2013.
  29. 29.↵
    Centers for Disease Control and Prevention (CDC). Colorectal cancer: basic fact sheet. Publication #99–6949. Available from: http://www.cdc.gov/cancer/colorectal/pdf/Basic_FS_Eng_Color.pdf. Accessed July 23, 2013.
  30. 30.↵
    1. Moerbeek M
    . Randomization of clusters versus randomization of persons within clusters: which is preferable? Am Statist 2005;59:172–9.
    OpenUrl
  31. 31.↵
    1. Zauber AG,
    2. Lansdorp-Vogelaar I,
    3. Knudsen AB,
    4. Wilschut J,
    5. van Ballegooijen M,
    6. Kuntz KM
    . Evaluating test strategies for colorectal cancer screening: a decision analysis for the U.S. Preventive Services Task Force. Ann Intern Med 2008;149:659–69.
    OpenUrlCrossRefPubMedWeb of Science
  32. 32.↵
    1. Miller WR,
    2. Rollnick S
    . Motivational interviewing: helping people change. 3rd ed. New York: Guilford Press; 2003.
  33. 33.↵
    1. Roetzheim RG,
    2. Christman LK,
    3. Jacobsen PB,
    4. et al
    . A randomized controlled trial to increase cancer screening among attendees of community health centers. Ann Fam Med 2004;2:294–300.
    OpenUrlAbstract/FREE Full Text
  34. 34.↵
    1. Shannon KC,
    2. Sinacore JM,
    3. Bennett SG,
    4. Joshi AM,
    5. Sherin KM,
    6. Deitrich A
    . Improving delivery of preventive health care with the comprehensive annotated reminder tool (CART). J Fam Pract 2001;50:767–72.
    OpenUrlPubMedWeb of Science
  35. 35.↵
    1. Sequist TD,
    2. Zaslavsky AM,
    3. Marshall R,
    4. Fletcher RH,
    5. Ayanian JZ
    . Patient and physician reminders to promote colorectal cancer screening: a randomized controlled trial. Arch Intern Med 2009;169:364–71.
    OpenUrlCrossRefPubMedWeb of Science
  36. 36.↵
    1. Shojania KG,
    2. Jennings A,
    3. Mayhew A,
    4. Ramsay CR,
    5. Eccles MP,
    6. Grimshaw J
    . The effects of on-screen, point of care computer reminders on processes and outcomes of care. Cochrane Database Syst Rev 2009;(3):CD001096.
    OpenUrlCrossRefPubMed
  37. 37.↵
    1. Arditi C,
    2. Rèege-Walther M,
    3. Wyatt JC,
    4. Durieux P,
    5. Burnand B
    . Computer-generated reminders delivered on paper to healthcare professionals; effects on professional practice and health care outcomes. Cochrane Database Syst Rev 2012;12:CD001175.
    OpenUrlPubMed
  38. 38.↵
    1. Myers RE,
    2. Sifri R,
    3. Hyslop T,
    4. et al
    . A randomized controlled trial of the impact of targeted and tailored interventions on colorectal cancer screening. Cancer 2007;110:2083–91.
    OpenUrlCrossRefPubMedWeb of Science
  39. 39.↵
    1. Daly JM,
    2. Levy BT,
    3. Merchant ML,
    4. Wilbur J
    . Mailed fecal-immunochemical test for colon cancer screening. J Community Health 2010;35:235–9.
    OpenUrlCrossRefPubMed
  40. 40.↵
    1. Church TR,
    2. Yeazel MW,
    3. Jones RM,
    4. et al
    . A randomized trial of direct mailing of fecal occult blood tests to increase colorectal cancer screening. J Natl Cancer Inst 2004;96:770–80.
    OpenUrlAbstract/FREE Full Text
  41. 41.↵
    1. Walsh JM,
    2. Salazar R,
    3. Nguyen TT,
    4. et al
    . Healthy colon, healthy life: a novel colorectal cancer screening intervention. Am J Prev Med 2010;39:1–14.
    OpenUrlCrossRefPubMedWeb of Science
  42. 42.↵
    1. Hewitson P,
    2. Ward AM,
    3. Heneghan C,
    4. Halloran SP,
    5. Mant D
    . Primary care endorsement letter and a patient leaflet to improve participation in colorectal cancer screening: results of a factorial randomised trial. Br J Cancer 2011;105:475–80.
    OpenUrlCrossRefPubMedWeb of Science
  43. 43.↵
    1. Libby G,
    2. Bray J,
    3. Champion J,
    4. et al
    . Pre-notification increases uptake of colorectal cancer screening in all demographic groups: a randomized controlled trial. J Med Screen 2011;18:24–9.
    OpenUrlAbstract/FREE Full Text
  44. 44.↵
    1. van Roon AH,
    2. Hol L,
    3. Wilschut JA,
    4. et al
    . Advance notification letters increase adherence in colorectal cancer screening: a population-based randomized trial. Prev Med 2011;52:448–51.
    OpenUrlCrossRefPubMed
  45. 45.↵
    1. Myers RE,
    2. Ross EA,
    3. Wolf TA,
    4. Balshem A,
    5. Jepson C,
    6. Millner L
    . Behavioral interventions to increase adherence in colorectal cancer screening. Med Care 1991;29:1039–50.
    OpenUrlCrossRefPubMedWeb of Science
  46. 46.↵
    1. Hart AR,
    2. Barone TL,
    3. Gay SP,
    4. et al
    . The effect on compliance of a health education leaflet in colorectal cancer screening in general practice in central England. J Epidemiol Community Health 1997;51: 187–91.
    OpenUrlAbstract/FREE Full Text
  47. 47.↵
    1. Walsh JM,
    2. Karliner L,
    3. Burke N,
    4. Somkin CP,
    5. Pham LA,
    6. Pasick R
    . Physicians' approaches to recommending colorectal cancer screening: a qualitative study. J Cancer Educ 2010;25:385–90.
    OpenUrlPubMed
  48. 48.↵
    1. Dietrich AJ,
    2. Tobin JN,
    3. Cassells A,
    4. et al
    . Telephone care management to improve cancer screening among low-income women: a randomized, controlled trial. Ann Intern Med 2006;144:563–71.
    OpenUrlCrossRefPubMedWeb of Science
  49. 49.↵
    1. Ling BS,
    2. Schoen RE,
    3. Trauth JM,
    4. et al
    . Physicians encouraging colorectal screening: a randomized controlled trial of enhanced office and patient management on compliance with colorectal cancer screening. Arch Intern Med 2009;169:47–55.
    OpenUrlCrossRefPubMedWeb of Science
  50. 50.↵
    1. Segnan N,
    2. Senore C,
    3. Andreoni B,
    4. et al
    . Randomized trial of different screening strategies for colorectal cancer: patient response and detection rates. J Natl Cancer Inst 2005;97:347–57.
    OpenUrlAbstract/FREE Full Text
  51. 51.↵
    1. Whitlock EP,
    2. Lin JS,
    3. Liles E,
    4. Beil TL,
    5. Fu R
    . Screening for colorectal cancer: a targeted, updated systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 2008;149:638–58.
    OpenUrlCrossRefPubMedWeb of Science
  52. 52.↵
    1. Ornstein S,
    2. Nemeth LS,
    3. Jenkins RG,
    4. Nietert P
    . Colorectal cancer screening in primary care: translating research into practice. Med Care 2010;48:900–6.
    OpenUrlCrossRefPubMedWeb of Science
  53. 53.↵
    1. Klabunde C,
    2. Lanier D,
    3. Breslau ES,
    4. et al
    . Improving colorectal cancer screening in primary care practice: innovative strategies and future directions. J Gen Intern Med 2007;22:1195–205.
    OpenUrlCrossRefPubMedWeb of Science
  54. 54.↵
    1. Levy BT,
    2. Daly JM,
    3. Schmidt E,
    4. Xu Y
    . The need for office systems to improve colorectal cancer screening. J Prim Care Community Health 2012;3:180–6.
    OpenUrlAbstract/FREE Full Text
  55. 55.↵
    Centers for Disease Control and Prevention (CDC). Vital signs: colorectal cancer screening among adults aged 50–75 years–United States, 2008. MMWR Morb Mortal Wkly Rep 2010;59:808–12.
    OpenUrlPubMed
  56. 56.↵
    1. Klabunde CN,
    2. Cronin KA,
    3. Breen N,
    4. Waldron WR,
    5. Ambs AH,
    6. Nadel MR
    . Trends in colorectal cancer test use among vulnerable populations in the United States. Cancer Epidemiol Biomarkers Prev 2011;20:1611–21.
    OpenUrlAbstract/FREE Full Text
  57. 57.↵
    1. Fan L,
    2. Mohile S,
    3. Zhang N,
    4. Fiscella K,
    5. Noyes K
    . Self-reported cancer screening among elderly Medicare beneficiaries: a rural-urban comparison. J Rural Health 2012;28:312–9.
    OpenUrlCrossRefPubMedWeb of Science
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The Journal of the American Board of Family     Medicine: 26 (5)
The Journal of the American Board of Family Medicine
Vol. 26, Issue 5
September-October 2013
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A Randomized Controlled Trial to Improve Colon Cancer Screening in Rural Family Medicine: An Iowa Research Network (IRENE) Study
Barcey T. Levy, Yinghui Xu, Jeanette M. Daly, John W. Ely
The Journal of the American Board of Family Medicine Sep 2013, 26 (5) 486-497; DOI: 10.3122/jabfm.2013.05.130041

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A Randomized Controlled Trial to Improve Colon Cancer Screening in Rural Family Medicine: An Iowa Research Network (IRENE) Study
Barcey T. Levy, Yinghui Xu, Jeanette M. Daly, John W. Ely
The Journal of the American Board of Family Medicine Sep 2013, 26 (5) 486-497; DOI: 10.3122/jabfm.2013.05.130041
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