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Review ArticleClinical Review

Safety and Efficacy of Ibutilide in Cardioversion of Atrial Flutter and Fibrillation

Madhuri Nair, Lekha K. George and Santhosh K. G. Koshy
The Journal of the American Board of Family Medicine January 2011, 24 (1) 86-92; DOI: https://doi.org/10.3122/jabfm.2011.01.080096
Madhuri Nair
MD
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Lekha K. George
MD
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Santhosh K. G. Koshy
MD
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    Table 1.

    Comparison of the Conversion Rates of Ibutilide, Amiodarone, Propafenone, Procainamide, Dofetilide, and Flecainide in Recent-Onset Atrial Fibrillation, Persistent Atrial Fibrillation, and Recent-Onset Atrial Flutter

    Pharmacological AgentConversion Rates (%)
    Recent-Onset Atrial FibrillationPersistent Atrial Fibrillation/FlutterRecent-Onset Atrial Flutter
    Ibutilide31–7711,16,18481263–7617,22
    Amiodarone34–69 (with bolus regimen)2315–4824–292916
    55–95 (with bolus followed by continuous infusion)
    Propafenone56–87.530,3137.5–4031,324033
    Procainamide20–6034,351436
    Dofetilide243720 (dose of 125 mcg bid)6437
    44 (250 mcg bid)
    85 (500 mcg bid) 38
    66.7 atrial flutter39
    Flecainide57–68 (at 2–4 hr)18,4013 (with intravenous administration)41
    75–91 (at 8 hr)40
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The Journal of the American Board of Family Medicine: 24 (1)
The Journal of the American Board of Family Medicine
Vol. 24, Issue 1
January-February 2011
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Safety and Efficacy of Ibutilide in Cardioversion of Atrial Flutter and Fibrillation
Madhuri Nair, Lekha K. George, Santhosh K. G. Koshy
The Journal of the American Board of Family Medicine Jan 2011, 24 (1) 86-92; DOI: 10.3122/jabfm.2011.01.080096

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Safety and Efficacy of Ibutilide in Cardioversion of Atrial Flutter and Fibrillation
Madhuri Nair, Lekha K. George, Santhosh K. G. Koshy
The Journal of the American Board of Family Medicine Jan 2011, 24 (1) 86-92; DOI: 10.3122/jabfm.2011.01.080096
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  • Article
    • Abstract
    • Use of Ibutilide in Chemical Cardioversion in Acute Atrial Fibrillation and Flutter
    • Use of Ibutilide in Postoperative Atrial Fibrillation and Flutter
    • Use of Ibutilide in Persistent Atrial Fibrillation and Flutter
    • Ibutilide Use in Terminating Accessory Pathway–Mediated Atrial Fibrillation
    • The Use of Ibutilide in Children
    • Use of Ibutilide in Acute Atrial Fibrillation in the Elderly
    • Adverse Effects of Ibutilide
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