LetterCorrespondence

Re: Effect of Antibiotics on Vulvovaginal Candidiasis: A MetroNet Study

Saira Tandon
The Journal of the American Board of Family Medicine March 2009, 22 (2) 223; DOI: https://doi.org/10.3122/jabfm.2009.02.080212

To the Editor: I read with great interest the recent article by Xu et al entitled “Effect of Antibiotics on Vulvovaginal Candidiasis” in the July issue of your journal.1 In their study they have highlighted a very common etiology for vulvovaginal candidiasis which is becoming all the more common now with widespread overuse of antibiotics.2 I understand their study was limited by numbers, but it would be interesting to know if they noted any association with a particular type of antibiotic. Previous studies have implicated certain antibiotics such as cephalosporins3 or fluoroquinolones,4 whereas others found no relation at all.5

References

  1. ↵
    Xu J, Schwartz K, Bartoces M, Monsur J, Severson RK, Sobel JD. Effect of antibiotics on vulvovaginal candidiasis: A MetroNet study. J Am Board Fam Med 2008 21: 261–8.
    OpenUrlAbstract/FREE Full Text
  2. ↵
    Xu J, Sobel JD. Antibiotic-associated vulvovaginal candidiasis. Curr Infect Dis Rep 2003; 5(6): 481–7.
    OpenUrlPubMed
  3. ↵
    MacDonald TM, Beardon PH, McGilchrist MM, Duncan ID, McKendrick AD, McDevitt DG. The risks of symptomatic vaginal candidiasis after oral antibiotic therapy. Q J Med 1993; 86: 419–24.
    OpenUrlAbstract/FREE Full Text
  4. ↵
    Menday AP. Symptomatic vaginal candidiasis after pivmecillinam and norfloxacin treatment of acute uncomplicated lower urinary tract infection. Int J Antimicrob Agents 2002; 20(4): 297–300.
    OpenUrlCrossRefPubMed
  5. ↵
    Spinillo A, Capuzzo E, Acciano S, De Santolo A, Zara F. Effect of antibiotic use on the prevalence of symptomatic vulvovaginal candidiasis. Am J Obstet Gynecol 1999; 180: 14–7.
    OpenUrlCrossRefPubMed
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