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Review ArticleClinical Review

Preventing Alcohol-exposed Pregnancies

Mark B. Mengel, H. Russell Searight and Keely Cook
The Journal of the American Board of Family Medicine September 2006, 19 (5) 494-505; DOI: https://doi.org/10.3122/jabfm.19.5.494
Mark B. Mengel
MD, MPH
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H. Russell Searight
PhD
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Keely Cook
MPAS, PA-C
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  • Article
  • Figures & Data
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Article Figures & Data

Tables

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    Table 1.

    Risk Factors for an Alcohol-exposed Pregnancy

    References
    Age: >3089, 103
    Caucasian103
    Hx binge drinking or long history of drinking91–93
    College educated103
    Low or high SES94, 97
    Special Education populations90
    Poor Native Americans90
    Hx of physical/sexual abuse ever51
    Hx of physical abuse in past year103, 105
    Heavy drinking by male partner or any family member95, 97, 98
    Loss of children to foster/adoptive care94, 95, 99
    Poly-drug use/cigarette smoking92, 93, 96, 104
    Previous child with FAS95
    Major depressive disorder51, 100, 104
    Post traumatic stress disorder51
    Unmarried89, 98
    Early age of drinking onset101, 102
    • Hx, history.

    • View popup
    Table 2.

    Screening Tools for Alcohol Use during Pregnancy

    ContentTime RequiredScoring and Cut-Off ScoreSensitivitySpecificity
    Quantity/Frequency Questions (3)Days per week of drinking Average number of drinks per day Maximum number of drinks consumed in 1 day during the past month2 minutes>7 drinks per week or >3 drinks per dayN/AN/A
    TWEAK47
    • Tolerance: (a) How many drinks does it take before you feel high (the first effects of alcohol)? or (b) How many drinks can you hold? (How many drinks does it take before the alcohol makes you fall asleep or pass out? If you never pass out, what is the largest number of drinks you have?)

    • Worried: Have your friends or relatives worried about your drinking in the past year?

    • Eye opener: Do you sometimes take a drink in the morning when you first get up?

    • Amnesia: Are there times when you drink and afterwards can’t remember what you said or did?

    • K/Cut Down: Do you sometimes feel the need to cut down on your drinking?

    3 to 5 minutesTolerance: (a) 3 drinks or more or (b) 5 drinks or more + 2 points Positive response to other questions = 1 point each Cut-off = 2 points0.79–0.910.77–0.83
    T-ACE48
    • Tolerance: How many drinks does it take to make you feel high?

    • Annoyed: Have people ever annoyed you by criticizing your drinking?

    • Cut Down: Have you ever felt that you needed to cut down on your drinking?

    • Eye opener: Have you ever had a drink first thing in the morning to steady your nerves or get rid of a hang over?

    2 to 3 minutesTolerance: 2 points if requires more than 2 drinks Other questions: 1 point each Cut off: 2 points0.70–0.890.79–0.85
    • View popup
    Table 3.

    Barriers to Providing Screening, Assessment, Brief Intervention, and Referral Services to Prevent Alcohol-exposed Pregnancies

    • Non-therapeutic attitude among family medicine physicians

      A public health concern, not a clinical problem

      A concern that questioning about alcohol use will lead to patient resistance, discomfort, and exiting from the practice

      Other health problems are more urgent or important

      Denial that drinking is a problem

      Feeling that treatment isn’t effective

    • Inadequate knowledge and clinical skills

      Limited training in medical school and residency

      Feel ill-prepared to deal with the realities of screening and assessment

      Lack of provider self-efficacy, feeling you can’t make a difference

      Provider reference material lacks information and consistent recommendation to abstain

    • Lack of time

    • Inadequate reimbursement

    • System barriers

      Lack of intervention tools

      Lack of a system strategy or protocol

      Lack of treatment and referral resources

      Lack of office staff involvement

    • Legal barriers

    • View popup
    Table 4.

    Common Myths Regarding Alcohol Use during Pregnancy

    1. Less than 1 drink per day in pregnancy is okay.
    2. Drinking late in pregnancy is okay and makes labor easier.
    3. Beer and wine are not alcohol, and thus are not a problem.
    4. If I drank and have one child without FAS, I can drink and I won’t have another child with FAS.
    5. If FAS doesn’t run in my family, my child won’t get FAS.
    6. FAS is curable if diagnosed early.
    • View popup
    Table 5.

    Organizing Your Office to Facilitate Preventing AEP

    ActivityStrategies
    ScreeningInclude alcohol screening questions on initial patient questionnaires or instruct medical assistants to assess alcohol use while assessing vital signs during initial patient intake.
    AssessmentConstruct a questionnaire or checklist for the nurse to perform the assessment if screening is positive prior to the physician seeing the patient or construct a checklist that the physician can use if initial screening questions are positive while visiting with the patient in the examination room
    Education (on alcohol and contraceptive practices)The clinic nurse can provide alcohol-exposed pregnancy (AEP) prevention education during preconception counseling visits, contraceptive initiation visits, or pregnancy education visits. Posters and brochures on AEP can be placed in waiting rooms and examination rooms.
    Brief interventionsNurses can be trained to conduct brief interventions and follow-up visits can be conducted by telephone. Brief intervention materials can be kept in the examination rooms for physicians to use.
    • View popup
    Table 6.

    Strength of Evidence: Preventing Alcohol-exposed Pregnancies Summary Statement of Evidence

    Grade
    1. Fetal alcohol syndrome (FAS) occurs in 0.3 to 1.5/1000 live births in the United StatesB
    2. Fetal alcohol effects occur in at least 1/100 live births in the United StatesB
    3. Approximately one-half of all childbearing-aged women in the United States drink alcoholC
    4. Approximately 10% of all women drink alcohol while pregnantC
    5. Although binge drinking (more than 3 drinks on one occasion) demonstrates the strongest adverse effect on the developing fetus, there is no safe level of alcohol consumption during pregnancyC
    6. With prenatal patients, the T-ACE and TWEAK are more effective screening measures than the CAGE.C
    7. Screening for alcohol use in routine office visits will decrease patients’ alcohol consumption.B
    8. Brief physician education and intervention about alcohol use in childbearing-aged women will reduce alcohol use, increase effective contraception or both.B
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The Journal of the American Board of Family Medicine: 19 (5)
The Journal of the American Board of Family Medicine
Vol. 19, Issue 5
September-October 2006
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Preventing Alcohol-exposed Pregnancies
Mark B. Mengel, H. Russell Searight, Keely Cook
The Journal of the American Board of Family Medicine Sep 2006, 19 (5) 494-505; DOI: 10.3122/jabfm.19.5.494

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Preventing Alcohol-exposed Pregnancies
Mark B. Mengel, H. Russell Searight, Keely Cook
The Journal of the American Board of Family Medicine Sep 2006, 19 (5) 494-505; DOI: 10.3122/jabfm.19.5.494
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  • Article
    • Abstract
    • Potential Outcomes of Alcohol Use During Pregnancy
    • Alcohol Exposure Issues during Pregnancy
    • Prevalence of Drinking in Childbearing-aged Women
    • Risk Factors for an Alcohol-Exposed Pregnancy
    • Screening for Prenatal Alcohol Use
    • Screening Tools
    • Clinical Issues with Screening Measures
    • Overview of Brief Intervention in Primary Care
    • Brief Intervention among Pregnant Women
    • Brief Intervention: Evidence for Effectiveness in Reducing AEP
    • Barriers to AEP Prevention in Clinical Practice
    • Conclusion
    • Notes
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

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