Screening for Dementia: Family Caregiver Questionnaires Reliably Predict Dementia

Article Figures & Data

Table 1.

University of Oklahoma Health Sciences Center Dementia Database Categories with Demographic Percentages and Comparisons with State Census Figures

Category	University of Oklahoma Database/2000 Oklahoma Census^* (%)
Female	63 /50.9
Male	37 /49.1
White	87 /80.3
African American	8 /8.3
Native American	4 /11.4
Asian	1 /1.7
Demented	73
Not demented	27
Alzheimer disease	27
Frontotemporal/Lewy body	25
Corticobasal ganglionic	11
Vascular dementia	6
Huntington disease	4
Mild cognitive impairment	9
Depression	8
Other neurological diseases	10

Table 2.

Results of ANOVA and Linear Regression Analyses of the Dependent and Independent Variables

Statistical Analysis	P	R² Adjusted	F Ratio	Patients with Dementia	Patients without Dementia
Demented (yes or no)× patient age	.007	0.03	7.3	72.2 ± 1.0 (patient age)	66.7 ± 1.7 (patient age)
Demented× MMSE	<.0001	0.28	72.4	18.7 ± 0.5 (MMSE)	26.1 ± 0.08 (MMSE)
Demented× modified CDR	<.0001	0.49	191.6	1.64 ± 0.05 (modified CDR)	0.35 ± 0.1 (modified CDR)
Demented× traditional CDR	<.0001	0.50	206.5	1.63 ± 0.05 (traditional CDR)	0.33 ± 0.17 (traditional CDR)
Demented× modified FBI	<.0001	0.11	15.6	22.1 ± 1.4 (modified FBI)	11.4 ± 2.3 (modified FBI)
Demented× Burden	.002	0.11	10.5	19.9 ± 3.3 (burden score)	43.3 ± 6.4 (burden score)
Demented× UCLA^*	.10	0.01	2.7
Demented× Yesavage^*	.15	0.02	2.1
Demented× Beck^*	.56	0.03	1.1
Demented× stress^*	.15	0.03	2.1

* Not significant.
Modified CDR, Clinical Dementia Rating scale: Y, yes; N, no; FBI, Frontal Behavioral Inventory; Burden, Caregiver Burden score; Yesavage, Yesavage Depression Rating Scale; Beck, Beck Depression Inventory; UCLA, UCLA Neuropsychiatric Inventory; MMSE, Mini-Mental State Exam.

Table 3.

Linear Regression Analyses Describing Relationships Between Covariates

Statistical Analysis	P	R² Adjusted	F Ratio	Test Results
Statistical Analysis	P	R² Adjusted	F Ratio	Demented	Nondemented
Modified CDR× MMSE	<.0001	0.52	95.4	CDR level 3 = mean MMSE 11	CDR level 0 = mean MMSE 27
Modified CDR × Burden	.0009	0.18	5.2	CDR level 3 = mean Burden index 5	CDR level 0 = mean Burden index 28
Modified CDR× modified FBI	<.0001	0.25	10.8	CDR level 3 = mean FBI score 37	CDR level 0 = mean FBI score 8
MMSE× Burden	<.0001	0.2	19.1	r = 0.31, P <.018	r = 0.74, P <.001
MMSE× modified FBI	<.0001	0.26	41.8	r =−0.44, P <.0000	r =−0.44, P <.017
Modified FBI× Burden	<.0001	0.37	39.0	r = −0.49, P <.0002	r =−0.8, P <.0003