Article Figures & Data
Tables
- Table 1.
Frequency of Edema in Controlled and Uncontrolled Trials of Different Antihypertensive Medications
Medication Reference Total Daily Dose (mg) Sample Size Edema (%) Dihydropyridine Calcium Channel Blockers Amlodipine Koenig, 199330 5–10 59 1.7 Frishman et al, 199531 2.5 82 3.8 Kuschnir et a., 199632 5 77 16.9 Corea et al, 199633 5 84 3.6 Corea et al, 199633 10 28 14.3 Messerli et al, 200029 5 144 15 Messerli et al, 200029 10 144 32 Kloner et al, 200134 5–10 127 22.1 Felodipine Freeling et al, 198735 2.5–10 32 28.1 Dahlof and Hosie,199036 10 53 18.9 Hammond and Cutler, 199337 5–10 71 29.6 Koenig, 199330 5–10 59 0.0 Fagan et al, 199426 5–10 137 12.4 Goldberg et al, 199524 Unspecified 43 14.0 Gradman et al, 199738 2.5–10 176 10.8 Schloze et al, 199939 5–10 84 7.1 Isradipine Hammond and Cutler, 199337 5–10 72 13.9 Eisner et al, 199140 2.5–10 78 7.7 Lacdipine UK Lacdipine, 199143 4 268 6.0 Nicardipine Gradman et al, 199241 45 73 8.2 Gradman et al, 199241 60 73 15.1 Nifedipine Daniels and Opie, 198623 40 35 11.4 Heagerty et al, 198825 20–40 210 12.4 Fagan et al, 199426 30–90 140 20.0 Steiner and Pauly, 199427 40 55 12.7 Brown et al, 200028 30–60 3,157 28.4 Messerli et al, 200129 30 130 5.4 Messerli et al, 200129 60 129 22.3 Nisoldipine Ruddy and Fodor, 199742 10–40 138 18.8 Nitrendipine Gennari et al, 198944 10 12 16.7 Morgan et al, 199045 20–40 38 5.3 Nondihydropyridine Calcium Channel Blockers Diltiazem Pool et al, 198658 120–360 45 8.9 Weir et al, 198760 240–360 39 2.6 Hedner et al, 199059 120–360 63 4.8 Ruddy et al, 199561 180–360 54 5.6 Ruddy et al, 199561 180–360 57 8.8 Nilsson et al, 199662 240–420 138 2–7 Cushman et al, 199857 120 150 2.7 Cushman et al, 199857 180 152 3.3 Verapamil Speders, 198951 240–480 4,247 0.7 Gradman et al, 199242 240 72 4.2 Karlberg et al, 200052 240 96 13.5 White et al, 200150 180–540 580 2.8 α-Blockers Doxazosin Ott et al, 198772 1–16 63 12.7 Prazosin Melkid, 198480 2–4 79 10.1 Goldberg et al, 198824 2–20 193 22.3 Angiotensin-Converting Enzyme Inhibitors Benazapril Frishman et al, 199531 10 85 1.2 Kushnir et al, 199632 20 77 1.3 Captopril Gennari et al, 198944 50 12 0.0 MacLean, 199488 50 29 0.0 Enalapril Eisner et al, 199140 5–40 82 0.0 Gradman et al, 199738 5–20 133 3.8 Cushman et al, 199857 5 144 3.5 Lisinopril Ruddy and Fodor, 199742 5–20 140 2.9 Ramipril Schloze et al, 199939 2.5–10 125 0.0 Trandolapril Steiner and Pauly, 199427 2 54 7.4 Karlberg et al, 200052 2 96 4.2 Captopril, Enalapril, or Lisinopril Goldberg et al, 199524 Unspecified 239 1.7 Enalapril or Lisinopril Hansson et al, 199911 10 2,205 8.7 Angiotensin Receptor Blockers Candesartan Kloner et al, 200134 16–32 123 8.9 Irbesartan Oparil et al, 2001103 150 145 0.7 Losartan Goldberg et al, 199524 Unspecified 2,085 1.7 Oparil et al, 2001103 50 146 0.0 Dahlof et al, 2002105 50–100 4,605 11.7 Olmesartan Neutel, 2001102 2.5–80 2,540 0.8 Oparil et al, 2001103 20 145 0.7 Valsartan Corea et al, 199633 80 84 2.4 Oparil et al, 2001103 80 142 2.1 Biswas et al, 2002104 Unspecified 12,881 1.4 β-Blockers Atenolol Daniels and Opie, 198623 100 35 5.7 Ott et al, 198772 50–100 63 6.3 Weir et al, 198760 50–100 39 2.6 Heagerty et al, 198825 50–100 200 1.0 UK Lacdipine, 199143 50 265 3.8 Goldberg et al, 199524 Unspecified 68 1.5 Dahlof et al, 2002105 50–100 4,588 13.9 Carvedilol Morgan et al, 199045 12.5–50 103 0.0 Dilavelol Materson et al, 1989112 200–1600 310 1.0 Metoprolol Freeling et al, 198735 100 32 0.0 Materson et al, 1989112 100–400 137 2.9 Hedner et al, 199059 50–200 63 4.8 Feliciano et al, 1990113 100–400 126 3.2 Dahlof and Hosie, 199036 100 52 0.0 Pindolol Morgan et al, 199045 Unspecified 39 0.0 Diuretics HCTZ Goldberg et al, 199524 Unspecified 27 1.8 HCTZ plus amiloride Brown et al, 200028 25–50/2.5–5 3,164 4.3
Jump to section
Related Articles
Cited By...
- No citing articles found.