Article Figures & Data
Tables
- Table 1.
Characteristics of 57,681 GHC Women Who Obtained Diagnostic and Screening Mammograms between 1996 and 2001
Diagnostic exams (N = 13,524 exams) Screening exams (N = 110,323 exams) Number of women 11,334 46,347 Mean SD Mean SD Age 61.3 11.0 62.9 10.9 BMI (kg/m2) 27.2 6.3 27.2 6.4 N % N % Family history of breast cancer 5,112 37.8 40,378 36.6 Hormone therapy use Never 1,300 21.6 32,906 32.1 Former user 2,231 37.1 19,446 19.0 Current user 2,479 41.2 50,209 49.0 Unknown 7,514 7,762 Previous biopsy 3,513 26.0 22,603 20.5 Reported any symptom 4,275 31.6 5,177 4.7 Diagnosed with breast cancer* 666 4.9 723 0.7 Prior mammogram history† No mammogram within 3 years 520 8.8 7,531 21.5 Mammogram without symptoms 4,645 78.3 25,792 73.7 Mammogram with symptoms 769 13.0 1,682 4.8 * Women were followed-up for 12 months after each exam for a breast cancer diagnosis.
† Includes only women with exams from 1999 to 2001. N = 5,934 with diagnostic exams and 35,005 with screening exams.
- Table 2.
Breast Cancer Rates* and Adjusted Odds Ratios† (OR) with 95% Confidence Intervals (CI) for Breast Cancer Associated with Breast Symptoms
Symptom‡ Diagnostic Exams Screening Exams N Breast Cancer OR (95% CI) N Breast Cancer OR (95% CI) N Rate N Rate None 9,249 383 41 1.0 105,146 656 6 1.0 Any 4,275 283 66 2.0 (1.6, 2.3) 5,177 67 13 2.1 (1.6, 2.7) Lump 2,745 229 83 2.8 (2.3, 3.4) 1,740 38 22 3.6 (2.6, 5.0) Nipple discharge 470 25 53 1.5 (1.0, 2.3) 873 10 11 1.8 (1.0, 3.4) Pain 287 15 52 1.4 (0.8, 2.4) 694 6 9 1.5 (0.7, 3.4) Other 1,400 58 41 1.2 (0.9, 1.6) 2,672 20 7 1.2 (0.8, 1.9) * Rate of breast cancer diagnoses per 1000 women per year.
† Adjusted for age, body mass index, family history of breast cancer, previous breast biopsy, and hormone therapy use.
‡ Symptom categories are not mutually exclusive.
- Table 3.
Breast Cancer Rates* among 40,939 Symptomatic and Asymptomatic Women Stratified by Diagnostic and Screening Exams, Prior Mammogram History, and Symptom History†
Symptom‡ Diagnostic Exams (N = 5,934) Screening Exams (N = 35,005) No Prior Exam (N = 520) Prior Exam with No Symptoms (N = 4,645) Prior Exam with Symptoms† (N = 769) No Prior Exam (N = 7,531) Prior Exam with No Symptoms (N = 25,792) Prior Exam with Symptoms† (N = 1,682) N Breast Cancer Rate* N Breast Cancer Rate* N Breast Cancer Rate* N Breast Cancer Rate* N Breast Cancer Rate* N Breast Cancer Rate* None 132 15 3,885 45 248 61 7,142 3 24,714 2 1,394 5 Any 388 111 760 101 521 48 389 3 1,078 9 288 10 Lump 243 136 504 133 294 61 104 10 236 34 104 19 Nipple discharge 44 182 72 42 65 31 69 0 146 7 62 16 Pain 48 125 88 57 129 0 120 0 404 0 79 0 Other 138 87 235 55 179 34 194 0 578 2 115 0 * Rate of breast cancer diagnoses per 1000 women per year.
† Symptoms reported at prior examination could have been any symptoms.
‡ Symptom categories are not mutually exclusive.
- Table 4.
Adjusted* Odds Ratios (OR) with 95% Confidence Intervals (CI) for Breast Cancer among Symptomatic Women Compared with Asymptomatic Women Stratified by Diagnostic and Screening Exams, Prior Screening History, and Symptom History†
Symptom‡ Diagnostic Exams Screening Exams No Prior Exam Prior Exam with No Symptoms Prior Exam with Symptoms† No Prior Exam Prior Exam with No Symptoms Prior Exam with Symptoms† Any 2.7 (2.0, 37.1) 2.9 (1.9, 4.3) 0.9 (0.4, 1.6) 1.0 (0.1, 7.4) 4.5 (2.3, 8.9) 2.1 (0.5, 8.3) Lump 12.2 (2.8, 53.5) 4.1 (2.7, 6.2) 1.2 (0.6, 2.5) 3.5 (0.5, 27.0) 17.2 (8.0, 37.1) 3.9 (0.8, 20.0) Nipple discharge 13.3 (2.6, 66.9) 1.0 (0.3, 3.4) 0.5 (0.1, 2.5) 3.0 (0.4, 22.1) 3.8 (0.5, 33.0) Pain 8.9 (1.6, 50.0) 1.5 (0.6, 4.0) Other 6.4 (1.4, 29.7) 1.5 (0.8, 2.9) 0.6 (0.2, 1.6) 0.8 (0.1, 6.0) * Adjusted for age, body mass index, family history of breast cancer, previous breast biopsy, and hormone therapy use.
† Symptoms reported at previous exam could have been any symptom.
‡ Symptom categories are not mutually exclusive.