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Brief ReportBrief Report

Recombinant Factor VIIa for Uncontrolled Bleeding in 2 Different Cases of Coagulopathy

Jamal Islam, Syed Azhar, Jack B. Alperin and Irshad Syed
The Journal of the American Board of Family Practice November 2003, 16 (6) 549-552; DOI: https://doi.org/10.3122/jabfm.16.6.549
Jamal Islam
MD, MS
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Syed Azhar
MD, MBA
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Jack B. Alperin
MD
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Irshad Syed
MD
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References

  1. ↵
    Vlot AJ, Ton E, Mackaay AJC, Kramer MHH, Gaillard CA. Treatment of a severely bleeding patient without preexisting coagulopathy with activated recombinant factor VII. Am J Med 2000; 108: 421–42.
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  2. ↵
    White B, McHale J, Ravi N, et al. Successful use of recombinant FVIIa (NovoSeven) in the management of intractable post-surgical intrabdominal hemorrhage [letter] Br J Haematol 1999; 107: 677–67.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    Jeffers L, Bernstein DE, Erhardsten E, et al. The use of recombinant factor VIIa in laparoscopy liver biopsy: a pilot trial [abstract]. Gastroentrology 1998; 114: L0275.
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    Martinowitz U, Kenet G, Segal E, et al. Recombinant activated factor VII for adjunctive hemorrhage control in trauma. J Trauma 2001; 51: 431–8.
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  5. ↵
    O’Neill PA, Bluth M, Gloster ES, et al. Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathy. J Trauma 2002; 52: 400–5.
    OpenUrlPubMedWeb of Science
  6. ↵
    Berntorp E. Recombinant FVIIa in the treatment of warfarin bleeding. Semin Thromb Hemost 2000; 26: 433–5.
    OpenUrlCrossRefPubMedWeb of Science
  7. ↵
    Makris M, Greaves M, Phillips WS, et al. Emergency oral anticoagulant reversal: the relative efficacy of infusions of fresh frozen plasma and clotting factor concentrate on correction of the coagulopathy. Thromb Haemost 1997; 77: 477–0.
    OpenUrlPubMedWeb of Science
  8. ↵
    Lusher JM. Factor IX concentrates. In: Forbes CD, Aledrt L, Madhok R, editors. Haemophilia. London: Chapman & Hall Medical; 1997. p. 203–11.
  9. ↵
    vanDam-Nieras MC, Hemker HC. Half-life time and control frequency of vitamin K dependent coagulation factors. Theoretical considerations on the place of factor VII in the control of oral anticoagulation therapy. Haemostasis 1983; 13: 201–8.
    OpenUrlPubMed
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The Journal of the American Board of Family Practice: 16 (6)
The Journal of the American Board of Family Practice
Vol. 16, Issue 6
1 Nov 2003
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Recombinant Factor VIIa for Uncontrolled Bleeding in 2 Different Cases of Coagulopathy
Jamal Islam, Syed Azhar, Jack B. Alperin, Irshad Syed
The Journal of the American Board of Family Practice Nov 2003, 16 (6) 549-552; DOI: 10.3122/jabfm.16.6.549

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Recombinant Factor VIIa for Uncontrolled Bleeding in 2 Different Cases of Coagulopathy
Jamal Islam, Syed Azhar, Jack B. Alperin, Irshad Syed
The Journal of the American Board of Family Practice Nov 2003, 16 (6) 549-552; DOI: 10.3122/jabfm.16.6.549
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