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Review ArticleClinical Review

Pharmacotherapy of Panic Disorder: Proposed Guidelines for the Family Physician

Peter Roy-Byrne, Murray Stein, Alexander Bystrisky and Wayne Katon
The Journal of the American Board of Family Practice July 1998, 11 (4) 282-290; DOI: https://doi.org/10.3122/jabfm.11.4.282
Peter Roy-Byrne
From the Department of Psychiatry and Behavioral Sciences (PRB, WK), University of Washington School of Medicine, Seattle, the Department of Psychiatry (MS), University of California at San Diego, and the Department of Psychiatry (AB), University of California at Los Angeles. Address reprint requests to Peter Roy-Byrne, MD, Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, 325 Ninth Ave, Box 359911, Seattle, WA 98104
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Murray Stein
From the Department of Psychiatry and Behavioral Sciences (PRB, WK), University of Washington School of Medicine, Seattle, the Department of Psychiatry (MS), University of California at San Diego, and the Department of Psychiatry (AB), University of California at Los Angeles. Address reprint requests to Peter Roy-Byrne, MD, Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, 325 Ninth Ave, Box 359911, Seattle, WA 98104
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Alexander Bystrisky
From the Department of Psychiatry and Behavioral Sciences (PRB, WK), University of Washington School of Medicine, Seattle, the Department of Psychiatry (MS), University of California at San Diego, and the Department of Psychiatry (AB), University of California at Los Angeles. Address reprint requests to Peter Roy-Byrne, MD, Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, 325 Ninth Ave, Box 359911, Seattle, WA 98104
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Wayne Katon
From the Department of Psychiatry and Behavioral Sciences (PRB, WK), University of Washington School of Medicine, Seattle, the Department of Psychiatry (MS), University of California at San Diego, and the Department of Psychiatry (AB), University of California at Los Angeles. Address reprint requests to Peter Roy-Byrne, MD, Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, 325 Ninth Ave, Box 359911, Seattle, WA 98104
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Abstract

Background: Efforts to improve the recognition and treatment of panic disorder in the primary care setting have not resulted in better outcomes. Studies show that even when physicians recognize panic disorder, they do not treat it adequately. Family physicians need specific diagnostic and treatment guidelines when they encounter a patient who has possible panic disorder.

Methods: Four psychiatrists with expertise in the pharmacotherapy of panic disorder and experience working in the primary care setting reviewed the available treatment literature and developed a consensus treatment algorithm for panic pharmacotherapy in the primary care setting. These proposed guidelines were reviewed for accuracy by 3 additional psychiatric experts and for their applicability to the primary care setting by 2 leading experts on the treatment of mental disorders in primary care.

Results: Guidelines for medication selection, dosing, titration, side-effect management, and maintenance treatment are proposed. Modifications for patients already on psychotropic medication are provided, and indications for psychiatric consultation are specified.

Conclusions: Panic disorder is a highly treatable condition, and primary care physicians can deliver effective pharmacotherapy if specific guidelines are carefully followed.

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The Journal of the American Board of Family     Practice: 11 (4)
The Journal of the American Board of Family Practice
Vol. 11, Issue 4
1 Jul 1998
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Pharmacotherapy of Panic Disorder: Proposed Guidelines for the Family Physician
Peter Roy-Byrne, Murray Stein, Alexander Bystrisky, Wayne Katon
The Journal of the American Board of Family Practice Jul 1998, 11 (4) 282-290; DOI: 10.3122/jabfm.11.4.282

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Pharmacotherapy of Panic Disorder: Proposed Guidelines for the Family Physician
Peter Roy-Byrne, Murray Stein, Alexander Bystrisky, Wayne Katon
The Journal of the American Board of Family Practice Jul 1998, 11 (4) 282-290; DOI: 10.3122/jabfm.11.4.282
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