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Research ArticleOriginal Article

Hepatitis B Status of Hmong Patients

Dwenda K. Gjerdingen and Vang Lor
The Journal of the American Board of Family Practice September 1997, 10 (5) 322-328; DOI: https://doi.org/10.3122/jabfm.10.5.322
Dwenda K. Gjerdingen
MD
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Vang Lor
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Abstract

Background: This study was conducted to determine the hepatitis B status, by age, of Hmong patients attending a St. Paul family practice residency clinic.

Methods: The clinic records of 1585 Hmong patients 4 years of age and older were reviewed for information about hepatitis B status. Those without evidence of previous serologic testing or vaccination were invited to participate in the study by being tested for three hepatitis B virus (HBV) markers—hepatitis B surface antigen (HBsAg), antibody to HBsAg (anti-HBs), and hepatitis B core antibody (anti-HBc); those whose results were positive for HBsAg and anti-HBc were also tested for hepatitis B e antigen (HBeAg) and alanine aminotransferase (ALT). Patients whose results were positive for only anti-HBc had their serologic tests repeated after 3 or more months, and those patients whose results remained positive for only anti-HBc were offered the vaccine and further follow-up serologic tests.

Results: Of the 434 total participants, 77 (18 percent) had acute or chronic infection (HBsAg present). The rate of infection was highest-28 percent—in the group of patients 15 to 19 years old. Of 66 patients with positive test results only for anti-HBc, 33 of 36 (92 percent) who had follow-up serologic tests after 3 or more months had the same result again in the absence of intervention. Six of 8 (75 percent) patients with results positive only for anti-HBc who received hepatitis B vaccine subsequently converted to an immune status (anti-HBs positive). For all age groups, the cost of pretesting patients with an unknown HBV status and vaccinating susceptible patients was less than the cost of vaccinating without pretesting.

Conclusions: This study, which confirmed previous findings of a high occurrence of hepatitis B virus infection in Hmong refugee communities, found the highest rate of infection to be among adolescents. Prevaccination testing appeared to be a cost-saving procedure for patients whose hepatitis status was unknown.

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The Journal of the American Board of Family     Practice: 10 (5)
The Journal of the American Board of Family Practice
Vol. 10, Issue 5
1 Sep 1997
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Hepatitis B Status of Hmong Patients
Dwenda K. Gjerdingen, Vang Lor
The Journal of the American Board of Family Practice Sep 1997, 10 (5) 322-328; DOI: 10.3122/jabfm.10.5.322

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Hepatitis B Status of Hmong Patients
Dwenda K. Gjerdingen, Vang Lor
The Journal of the American Board of Family Practice Sep 1997, 10 (5) 322-328; DOI: 10.3122/jabfm.10.5.322
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