Discussion This case illustrates the value of a proactive approach to diagnosing Alzheimer
disease and the importance of initiating treatment early in the disease course. This case also …

The following case describes a severely demented, elderly male patient who was placed in
a nursing home when he became unmanageable in an assisted-living facility. Upon …

Alzheimer's disease is a large and increasing public health problem. Because the cognitive
deficits of the disease are thought to result from degeneration of cholinergic basal fore-brain …

Several studies have reported the efficacy of donepezil (a cholinesterase inhibitor) in
patients with Alzheimer's Disease, not only for memory disturbances but also for psychotic …

A 72-year-old woman is brought into the office by her daughter, who complains that her
mother has become increasingly forgetful over the past two years. On a Mini-Mental State …

Alzheimer's disease accounts for the majority of dementia cases, but a substantial number of
persons may be affected by other dementias, including vascular dementia (10 to 20 percent …

Alzheimer disease (AD) after the resumption of the deterioration process during
acetylcholinesterase inhibitor therapy. New drugs for AD, such as immunotherapy or …

Background Alzheimer's disease is characterized by memory and cognitive deficits
associated with losses of presynaptic cholinergic function in the brain. Agents that block …

Donepezil, the most frequently prescribed cholinesterase inhibitor for the treatment of
Alzheimer's disease, was marketed in 1997 on the basis of the results of 3-month and 6 …

Background: Alzheimer disease afflicts millions of older Americans, with an estimated cost to
society approaching $100 million annually. Family physicians will care for an increasing …